1,721,107 research outputs found
Moretto e il Rinascimento bresciano
No full textDossier sul pittore Alessandro Bonvicino detto il Moretto e sul Rinascimento bresciano
Moretto e il Rinascimento bresciano
No full textDossier sul pittore Alessandro Bonvicino detto il Moretto e sul Rinascimento bresciano
MITOMYCIN C MODULATION OF CORNEAL WOUND HEALING AFTER PHOTOREFRACTIVE KERATECTOMY IN HIGHLY MYOPIC EYES
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8.
PMID: 15691552 [PubMed - indexed for MEDLINE
Pricing and net profit of operating lease
No full textPurpose – The purpose of this paper is to investigate how asset risk (i.e. the risk that the value of
the leased asset loses unexpectedly most of its value at the end of the contract) is measured and
hedged.
Design/methodology/approach – The evaluation of the lease contract is achieved by applying the
theory of option pricing as the lessor is the writer of a call option on the leased asset. A sensitivity
analysis on some parameters is performed.
Findings – The paper disentangles the components of the profit of a lease contract and allows to
choose the optimal final purchase price. This lets the lessor hedge against asset risk.
Research limitations/implications – The paper’s result can be extended by considering more
complex options (such as American or exotic ones) into the lease contract.
Practical implications – Results in the paper allow for a more flexible and efficient management of
lease contracts where both parties benefit under an economic and a financial point of view.
Originality/value – This is believed to be the first paper that applies derivative evaluation to the
analysis of lease contracts.
Keywords Assets management, Leasing, Pricing, Profit, Hedging
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Using complex networks to model, simulate and understand the dynamics of psychotherapeutic processes: An experimental study proposal
No full textThe goal of our study was to utilize the science of complex interactions to bridge the gap in research concerning psychotherapy. In particular, we chose to focus on the use of graph theory to model and simulate the topology and dynamics of the psychotherapeutic relationship, given how in the past few years such method has been instrumental in understanding complex dynamic systems. © 2018 IEEE
An alternative model for evaluating exchange rates derivatives with stochastic volatility
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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