1,720,965 research outputs found
Porous Silicon Optical Devices: Recent Advances in Biosensing Applications
This review summarizes the leading advancements in porous silicon (PSi) optical-biosensors, achieved over the past five years. The cost-effective fabrication process, the high internal surface area, the tunable pore size, and the photonic properties made the PSi an appealing transducing substrate for biosensing purposes, with applications in different research fields. Different optical PSi biosensors are reviewed and classified into four classes, based on the different biorecognition elements immobilized on the surface of the transducing material. The PL signal modulation and the effective refractive index changes of the porous matrix are the main optical transduction mechanisms discussed herein. The approaches that are commonly employed to chemically stabilize and functionalize the PSi surface are described
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Design, fabrication and characterization of nanostructured hybrid bio/non-bio interfaces for biomolecular interactions study and industrial applications
Hybrid devices have one or more biological components bioconjugated with functional support surfaces preserving their specific activity and properties. They are extremely interesting from the biotechnological point of view since: 1)They provide a creative way to combine functional properties of different substances into a singular molecular composite; 2) They could show enhanced properties due to the coupling of different elements; 3)Their properties open innovative ways to applications in different fields, such as food, agriculture, medicine and so on.
The goal of this PhD thesis is the development of some hybrid-nanocomposites, made of nanostructured materials and biological elements, in which the key issue is the interface between the bio and non-bio components of the systems.
Bioconjugated nanostructured materials reveal peculiar physical and chemical properties that can boost their use in biotechnological applications. Inorganic nanoparticles, in particular those based on noble metals and semiconductors in native form or oxide, are becoming common tools in many popular fields of investigation such as nanomedicine, imaging, environmental monitoring and biomolecular sensing. Porous silicon (PSi), Gold nanoparticles (AuNPs) and Zinc Oxide (ZnO) are three highly-performing nanostructured systems whose features have been exploited in this thesis.
The research approach used in this work thesis is focused on the synthesis and fabrication of nanostructured support materials, in planar or in nanoparticle shapes, followed by the functionalization and passivation of the material surfaces. Finally, biological elements are immobilized on the solid supports for specific studies and applications. Different hybrid devices have been developed in this work for applications in several research areas, in particular:
Hybrid silicon-based device for the detection of Brugada Syndrome for diagnostic purposes; Luminescent silicon nanoparticles as label-free bioprobes for fluorescent bioimaging applications; Hybrid gold-copper nanoparticles as promising contrast agent in nuclear magnetic resonance;
Gold nanoparticles complexed to an antimicrobial peptide to enhance the antibacterial activity of the peptide.
The results obtained in each case highlighted the innovative potentialities of these nano-complexes in solving problems and breaking barriers in different ambits, spanning from diagnostic to healthcare
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
- …
