560 research outputs found
Zerovirgola istituzionali
No full textMassimiliano Tancioni si occupa della recente querelle tra Ministero dell’Economia e Ufficio Parlamentare di bilancio sulle previsioni macroeconomiche. Dopo aver ricordato che la certificazione delle previsioni macroeconomiche – e non solo dei bilanci pubblici – è un’implicazione del Fiscal Compact, Tancioni ricostruisce i passaggi del confronto sugli zerovirgola, illustra le difficoltà che avrebbero sconsigliato di richiedere una certificazione oggettiva sulle previsioni e, comunque, indica i modi migliori per farvi fronte
L’abbandono del vincolo valutario e le sue conseguenze. Un contributo al dibattito tra Biasco e Rodano
No full textMassimiliano Tancioni interviene nel dibattito tra Biasco e Rodano sugli effetti dell’abbandono del vincolo valutario, proponendo un ragionamento quantitativo basato su un modello che tiene conto dei punti sollevati da Biasco nella sua critica a Rodano. Svolgendo l’analisi in ottica comparativa, Tancioni giunge alla conclusione che uno scenario di uscita governato è in grado di produrre, nel medio termine, risultati macroeconomici migliori di quelli che scaturirebbero dalle politiche fiscali richieste dagli Obiettivi di Medio Termine
Trascurabili realtà. Lavoro produttivo e riproduttivo nelle «Ore migliori» di Giovanni Giudici
No full textThis paper discusses Giovanni Giudici’s Le ore migliori from both a literary and a political perspective. The poetry, originally conceived for L’educazione Cattolica (1963), will later be included in his first major poetical book, La vita in versi (1965): in his attempt to communicate the ambiguous impact of the Italian economic miracle on the average man, Giudici not only reflects in strictly Marxist terms (like labour and alienation), but focuses also on women’s conditions, in order to underline a common situation of servitude which compare them to men. Distinguishing between a productive and a reproductive side of labour, Giudici proves himself not only an avid reader, but also a precursor of that feminist struggle for salary which will not be fully emerging in Italian
debate until 1968
Antiplatelet agents in hemodialysis
No full textPatients affected by cardiovascular disease (CVD) are treated with antiplatelet agents (AA) and/or anticoagulant drugs, which are fundamental in the management of stroke, coronary atherosclerotic disease, peripheral vascular disease and atrial fibrillation. CVD is the most important cause of death in chronic renal failure (CRF). Death rates from myocardial infarction (MI) and from all other cardiac causes exceed those for the general population. Incidence of MI in CRF is triple that in the general population. Moreover, mortality is seven- to eight-fold higher in patients requiring chronic hemodialysis compared to the general population, and approximately 40% of deaths in this population are attributable to coronary artery disease (CAD). For these reasons, AA are widely used in patients affected by CRF. Current data do not support a protective effect of antiplatelet administration in hemodialytic patients as primary prevention of cardiovascular mortality. Different results have been obtained concerning secondary prevention of CVD. The Cooperative Cardiovascular Project demonstrated that dialysis patients treated with aspirin following MI had a 43% lower mortality. Another study reported that the use of aspirin and beta-blockers following MI was associated with lower mortality in CRF patients. However, aspirin plus clopidogrel seems to increase the hemorrhagic risk without a significant reduction in cardiovascular mortality and there are insufficient data to support the use of new AA drugs in hemodialytic patients. In conclusion, since CRF patients are one of the groups at highest risk for atherosclerotic events, it could be reasonable to use aspirin in HD patients. However, the bleeding risk in HD patients needs to be strongly evaluated, especially before starting dual AA treatment
Tudor Translation in Theory and Practice
No full textFilling a gap in the study of early modern literature, Massimiliano Morini here exhaustively examines the aims, strategies, practice and theoretical ideas of the sixteenth-century translator. Morini analyzes early modern English translations of works by French and Italian essayists and poets, including Montaigne, Castiglione, Ariosto and Tasso, and of works by classical writers such as Virgil and Petrarch. In the process, he demonstrates how connected translation is with other cultural and literary issues: women as writers, literary relations between Italy and England, the nature of the author, and changes in the English language. Since English Tudor writers, unlike their Italian contemporaries, did not write theoretical treatises, the author works empirically to extrapolate the theory that informs the practice of Tudor translation - he deduces several cogent theoretical principles from the metaphors and figures of speech used by translators to describe translation. Employing a good blend of theory and practice, the author presents the Tudor period as a crucial transitional moment in the history of translation, from the medieval tradition (which in secular literature often entailed radical departure from the original) to the more subtle modern tradition (which prizes the invisibility of the translator and fluency of the translated text). Morini points out that this is also a period during which ideas about language and about the position of England on the political and cultural map of Europe undergo dramatic change, and he convincingly argues that the practice of translation changes as new humanistic methods are adapted to the needs of a country that is expanding its empire
Role of the CD40-CD40 Ligand Pathway in Cardiovascular Events, Neurological Alterations, and Other Clinical Complications of Chronic Hemodialysis Patients: Protective Role of Adsorptive Membranes
No full textDespite the recent advances in dialysis technology, mortality rate of chronic uremic patients still remains excessively high: of note, in comparison to age- and sex-matched healthy controls, this frail population shows a higher incidence of infections, cancer, cognitive decline, and, in particular, major adverse cardiovascular events (MACE) that represent nowadays the first cause of mortality. Several traditional and nontraditional factors contribute to this increased risk for MACE and accelerated cellular senescence: among these, inflammation has been shown to play a key role. The costimulatory pathway CD40-CD40 Ligand (CD40L) is harmfully activated during inflammation and uremia-associated clinical complications: in particular, the soluble form of CD40L (sCD40L) can bind to the CD40 receptor triggering a cascade of detrimental pathways in immune and nonimmune cells. In this narrative review, we summarize the current concepts of the biological role of the CD40-CD40L pathway in uremia-associated organ dysfunction, focusing on the above-described main causes of mortality. Moreover, we discuss the interaction of the CD40-CD40L pathway with extracellular vesicles, microparticles recently identified as new uremic toxins. The biological effects of sCD40L in MACE, cognitive decline, infections, and cancer will be also briefly commented. Last, based on recent studies and ongoing clinical trials, we herein describe the modulatory activity of adsorptive dialysis membranes in polymethylmethacrylate on CD40-CD40L detrimental activation
The forearm arteriovenous graft between the brachial artery and the brachial vein as a reliable dialysis vascular access for patients with inadequate superficial veins
No full textThe arteriovenous fistula (AVF) is recommended as the preferred hemodialysis access. However, placing an AVF in all patients may result in poor access outcomes and increased central venous catheter (CVC) use because of increased comorbid conditions, age, and suboptimal vessels. In patients with inadequate superficial veins for AVFs, the use of the brachial veins for creation of forearm arteriovenous grafts (AVGs) has received limited attention. This retrospective study aimed to evaluate outcomes of forearm brachial-brachial AVGs (BB-AVGs) placed in patients with poor superficial veins
Outcomes of vascular access care and surgery managed by interventional nephrologists: A twelve-year experience
No full textBackground: Optimizing vascular access outcomes is still a challenge, since 30-60% of arteriovenous fistulas fail or do not mature and catheters are widely used in contemporary patients. Methods: This study reports on strategies and outcomes in a single center in which access planning, surgery and maintenance are managed by a team of nephrologists. We retrospectively analyzed 305 fistulas and 61 grafts created in 270 consecutive patients between 2002 and 2013. Results: The percentage of patients receiving a fistula or graft who initiated hemodialysis with a mature access was 68.6%. Among prevalent patients, 71.7% used a fistula, 15.7% a graft and 12.6% a catheter. Rates of primary failure and revision before cannulation were 14.4 and 1.6% for fistulas vs. 4.9 and 3.3% for grafts. After maturation, complications (1.040 vs. 0.188 per patient-year (py)) and interventions (0.743 vs. 0.066 per py) were greater for grafts than for fistulas (p < 0.001). Secondary patency did not significantly differ between grafts and fistulas (median survival 34.8 vs. 57.3 months, p = 0.36), unless primary failures were excluded from Kaplan-Meier analysis (median survival 34.9 vs. 70.9 months, p = 0.03). Conclusions: High fistula prevalence, low access-related morbidity and catheter dependence were achieved using individualized strategies, including mid-forearm or perforating vein fistula creation and selective graft placement in high risk patients. Direct involvement of nephrologists throughout all steps of access care can improve access outcomes, by promoting a patient-centered approach
Proposta di un modello per l’analisi dei fabbisogni formativi negli Enti pubblici di ricerca
No full textLa proposta di un modello per l'analisi dei fabbisogni formativi negli Enti pubblici di ricerca (EPR) è funzionale alla realizzazione di una ricerca azione promossa nell'ambito dell'Inapp Academy, un progetto condiviso con gli EPR, nato per condividere comuni conoscenze, competenze e migliori esperienze la cui sistematizzazione contribuisce alla promozione dello crescita professionale del personale del comparto attraverso lo sviluppo del capitale umano, la condivisione della conoscenza e l’organizzazione di incontri formativi peculiari che mirino all’innovazione delle competenze manageriali, gestionali, organizzative e digitali di tutto il management della ricerca.la proposta di un modello per l'analisi dei fabbisogni formativi negli enti pubblici di ricerca (epr) è funzionale alla realizzazione di una ricerca azione promossa nell'ambito dell'inapp academy, un progetto condiviso con gli epr, nato per condividere comuni conoscenze, competenze e migliori esperienze la cui sistematizzazione contribuisce alla promozione dello crescita professionale del personale del comparto attraverso lo sviluppo del capitale umano, la condivisione della conoscenza e l’organizzazione di incontri formativi peculiari che mirino all’innovazione delle competenze manageriali, gestionali, organizzative e digitali di tutto il management della ricerca. proposta di un modello per l’analisi dei fabbisogni formativi negli enti pubblici di ricerca massimiliano franceschett
The Faunæ Ligusticæ Fragmenta of Massimiliano Spinola (1805).
No full textDie Faunæ Ligusticæ Fragmenta, Decas Prima, 1805, waren der erste und einzige gedruckte Teil eines geplanten Werkes über die Insekten Liguriens. Er wurde auf Kosten seines Autors Massimiliano Spinola gedruckt. Soweit bekannt ist, blieb nur eine Kopie erhalten, da sein Autor kurzerhand und mit beinahe vollem Erfolg versuchte, ihn zu unterdrücken. Ob die Faunæ damit als valid publiziert gelten müssen oder nicht, wird diskutiert. Hier wird begründet, daß die Faunæ im strengen Sinne der Internationalen Regeln für die Zoologische Nomenklatur nicht gültig veröffentlicht worden sind und daß die wenigen Taxa, alle Hymenoptera, die darin beschrieben sind, mit den Namen bezeichnet werden sollten, einige etwas verändert, unter denen sie in den Insectorum Liguriæ, Bd. I, 1806, des gleichen Autors erstmals gültig publiziert wurden.StichwörterBibliography, Italy, Insecta, Hymenoptera.The Faunæ Ligusticæ Fragmenta, Decas Prima, 1805, was the first and only part to be printed of a projected work on the insects of Liguria. It was printed at the expense of its author, Massimiliano Spinola, and, so far as is known, only one copy survives, this primarily for the reason that its author shortly, and almost entirely successfully, sought to suppress it. Whether the Faunæ was or was not validly published has been disputed. It is argued here that the Faunæ was not validly published within a strict reading of the International Code of Zoological Nomenclature, and that the few taxa, all Hymenoptera, described in it should be known by the names, some altered, under which they were first validly published in the same author\u27s Insectorum Liguriæ, volume I, 1806.KeywordsBibliography, Italy, Insecta, Hymenoptera
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