1,721,252 research outputs found

    Architettura e digitale. Realtà estesa e intelligenza artificiale per progettazione, visualizzazione e costruzione architettonica

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    L’obiettivo di questa ricerca è investigare il rapporto tra architettura e tecnologie digitali, analizzando nello specifico il modo in cui la disciplina architettonica si interseca con la realtà estesa e l’intelligenza arti昀椀ciale generativa. Ciò è stato fatto organizzando il lavoro in due fasi, una di ricerca teorica, per costruire un solido riferimento per le successive analisi critiche, e una pratica, ovvero basata sul learning by doing. Quindi, inizialmente ci si è concentrati sulla ricostruzione della storia delle tecnologie immersive e dell’intelligenza artificiale, cercando di contestualizzarle e di comprendere quali siano stati e quali siano tutt’ora gli utilizzi che vengono fatti di questi strumenti, attingendo necessariamente a campi e approcci anche molto distanti da quelli puramente architettonici. La consapevolezza derivante da questo processo è stata immessa nella seconda fase, durante la quale si sono svolte una serie di esperienze in prima persona, applicando strumenti, tecniche e conoscenza raccolte a progetti e sperimentazioni architettoniche di varia natura: progettazione, didattica, valorizzazione e costruzione

    Evidences of carbonate preservation on the outer continental slope in the Western Ross Sea (Hallett Ridge and Central Basin, Antarctica)

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    Late Quaternary Antarctic Ice Sheet (AIS) changes can be investigated by analyzing marine sediments (gravity and box cores) collected on the continental shelves and along the continental margins of Antarctica. These sites are strongly influenced by the ice sheet/shelf sediment drainage and inflow/outflow of polar water masses. In this respect, the continental slope of the Western Ross Sea (WRS) is still poorly studied, in particular its history is affected by uncertainties due to the scarcity of well-preserved calcareous foraminifera preventing the production of reliable age models. We present the results of a study made on one gravity core (KI13-C2; Melis et al., 2021) and three box-cores (KI13-bc2, bc3 and bc4; Torricella et al., 2021) located on the Hallett Ridge and in the Central Basin where the presence of carbonate-rich intervals offers the opportunity, to time-reconstruct the AIS evolving changes since the Marine Isotopic Stage (MIS) 2. These intervals correlated with other carbonate layers identified in cores collected along the WRS continental slope provide important insights about a large-scale break-up of the ice shelf/sea ice system. This study has been conducted in the framework of the STREAM Project (Late Quaternary evolution of the ocean-ice sheet interactions: the record from the Ross Sea continental margin, Antarctica; period 2019-2021), funded by the Italian Ministry of Foreign Affairs and International Cooperation and the National Research Foundation of Korea, and thanks to a grant approved by the Department of Mathematics and Geoscience, University of Trieste. Bibliographic references Melis R., Capotondi L., Torricella F., Ferretti P., Geniram A., Hong J.K., Kuhn G., Khim B.-K., Kim S., Malinverno E., Yoo K.C. and Colizza E. (2021) - Last Glacial Maximum to Holocene: paleoceanography of the northwestern Ross Sea inferred from sediment core geochemistry and micropaleontology at Hallett Ridge. J. of Micropal., 40, 15-35. Torricella F., Melis R., Malinverno E., Fontolan G., Bussi M., Capotondi L., Del Carlo P., Di Roberto A., Geniram A., Kuhn G., Khim B.-K., Morigi C., Scateni B. and Colizza E. (2021) – Environmental and Oceanographic Conditions at the Continental Margin of the Central Basin, Northwestern Ross Sea (Antarctica) Since the Last Glacial Maximum. Geosciences, 11, 155

    Structural aspects of dynamic and DNA recognition of HPV-16 E2C protein

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    L’infezione da Papillomavirus Umano (HPV) è una delle maggiori cause eziologiche del tumore al collo dell'utero e rappresenta un grave problema di salute per le donne in tutto il mondo. La pur sperimentazione di vaccini non ha alcun effetto nel corso di infezione e il sia pur grande sforzo nella profilassi è controbilanciato dalla mancanza di accessibilità per la maggior parte della popolazione. Alla luce di queste considerazioni, non vi è la necessità di sviluppare farmaci antivirali specifici per prevenire le infezioni da HPV. Il mio lavoro di dottorato è stato incentrato sulla aspetti strutturali e funzionali del domonio C-terminale della proteina E2 del ceppo ad alto rischio HPV16 . (E2C) E2C è l'unico fattore di trascrizione codificati dal genoma virale e svolge un ruolo centrale nel controllare l'espressione di tutti i geni virale espressi nel ciclo vitale dell’HPVThe Human Papillomavirus (HPV) infection is linked to cervical cancer and represents a serious problem for women health worldwide .The existence of effective vaccines will not affect the course of infection , in particular those in developing countries and the tremendous prophylactic effect of the vaccine is counterbalanced by the lack of accessibility to most of the population. In view of these considerations, there is a need to develop specific antiviral drugs to prevent HPV infections. My PhD work was focused on the particular properties and structure-functional aspects of the E2 HPV16 DNA binding domain (E2C) E2C is the only transcription factor encoded by the viral genome and plays a central role in controlling the expression of all Papilomavirus genes and in regulating the virus life cycl

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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