1,721,118 research outputs found
Cocrystallization as a tool to stabilize liquid active ingredients
No full textCocrystallization is an extensively used method in Crystal Engineering for tuning the properties of target compounds by pairing them with ad-hoc selected molecular partners (i.e. coformers) in a stoichiometric ratio within the same crystal structure. The formation of a new intermolecular network significantly alters the physical–chemical properties of the final material, becoming crucial for target applications such as pharmaceutical, agrochemical and nuctraceutical where cocrystals are largely investigated. Although, the majority of the cocrystals reported in the literature so far are generally made of coformers which are solid at room temperature, there is no restriction in using liquid or low melting compounds as a coformer. This contribution aims at reviewing some significant cases and applications where cocrystallization is used to stabilize liquid ingredients, that are generally poorly stable and their manufacturing, transportation, and storage conditions present considerable environmental, logistical, and cost-related challenges
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF LOMEFLOXACIN IN SEMINAL PLASMA AFTER SOLID-PHASE EXTRACTION
No full textSIMULTANEOUS DETERMINATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE IN TABLETS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
No full textStratigraphic and Geochemical Study of Clastic Sediments of the Grotte di Stiffe Karstic System
No full textThe present work reports the results of a geochemical and stratigraphic study carried out on clastic sediments from the karstic system of the Grotte di Stiffe in Abruzzo. In order to describe in more significant manner the system from which the sediments have been taken, the rocks from which they derive and ground samples from the plateau immediately above the caves have also been examined. Stratigraphic and chemical studies, with particular regard to the presence of heavy metals, have been performed on some 50 cm of drawn sediment, utilising atomic absorption spectrophotometry. The data obtained in this way have been subjected to Principal Components Analysis in order to investigate possible correlations
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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