472 research outputs found

    Dental Education in Japan

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    application/pdfまず,我国における歯学教育について歴史的に展望し,歯科大学の前身である歯学院が1890年初めて出来て以来,第2次世界大戦後を経て現在に至るまでの変遷を述べた.次いで,松本歯科大学の教育システムについて言及した.松本歯科大学は1972年の創立であり,その教育内容は当初より6年制の一貫教育であり,多少の改善を加えつつ現在に至っている.しかしながら,近年に至り我国の大学という大学の教養課程の形骸化が問題となり,1991年7月に抜本的な大学教育の改革がなされた.その要点は,①教養課程を制度上廃止する ②カリキュラムの編成が各大学の自主性にまかされた ③シラバスの作成 ④自己点検・自己評価などである.そこで,本学でも1992年より,新たな教育改革に取り組むことになり検討を重ねてきたので,その概要につき述べた.journal articl

    Voice Compression and Communications: Principles and Applications for Fixes and Wireless Channels

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    Up-to-date, expert coverage of topics in wireless voice communications Voice communication is the most important facet of mobile radio service. Even when the predicted surge of wireless data and Internet services becomes a reality, voice will remain the most natural means of human communication. Voice Compression and Communications details issues in wireless voice communications and treats compression, channel coding, and wireless transmission as a joint subject. Part I covers background material, whereas Part II provides detailed information on both proprietary and standardized analysis-by-synthesis codecs, including the speech codecs of virtually all existing wireline-based and wireless systems. Parts III and IV discuss mainly research-based wideband, audio, as well as very low-rate schemes likely to find their way into future standards. Voice Compression and Communications describes fundamental concepts in a non-mathematical way early in the book for those with only a background knowledge of signal processing and communications. More advanced readers will find detailed discussions of theoretical principles, future concepts, and solutions to various specific wireless voice communications problems

    The Clarification of the Situation of Early Modern Education in Bhutan: 50 Years' History of Modern Education

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    特集4: 雲南懇話会からの寄稿 = Special Issue 4: Contribution from the Yunnan ForumThis study aims to clarify the situation of early modern education in the Kingdom of Bhutan during the 1910-1950s by analysing reliable documents like annual reports on the relations between the British Government and Bhutan written by successive political officers in Sikkim. The origins of modern education in Bhutan can be traced back approximately 100 years. According to a history textbook there, 1914 saw the inception of modern education when 46 boys travelled to study at Dr. Graham's Homes in Kalimpong, India. In the same year, Ugyen Dorji established Bhutan's first modern school in Haa District. Then in the following year, another school was established in Bumthang District for educating the Crown Prince and children of the people serving in the King's court. In the first half of this paper, the author tried to examine the various aspects of these schools and proposed some facts of them and their students. Instead of the elite education institutions for the selected few, schools for the general public were established in Bhutan in the 1940-1950s. These schools can be classifying into 'private schools for Nepali immigrants' which were privately established in response to the strong demands of local residents in Southern area and 'public schools for Bhutanese' which were established under the initiative of local government officials. In the second half of this paper, it mentioned representative examples of these contrasting schools and took up educational development plan and ambition by policy makers such as the Third King Ugyen Dorji Wangchuck and the first Prime Minister Jigme Palden Dorji

    A Comparative Study on Histopathological Aspects of Benign and Malignant Smooth Muscle Tumors appeared in Oral Regions

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    application/pdfHistopathological aspects of two cases of smooth muscle tumors appeared in oral regions (case 1: angiomyoma; case 2: leiomyosarcoma) have been described. Histopathological features of both cases showed a similarity in terms of relationship with blood vessels. In spite of the changes of cell structure and the destructive pattern of cell proliferation, the results as determined by special staining techniques were the same in the benign and malignant tumors. The histopathological features, origin, and differential diagnosis of the two types of tumors were also discussed.journal articl

    Experimental Production of Lingual Tumor by Jet Injection of 9, 10-dimethyl 1, 2-bemzamtjracene

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    application/pdfNinety-six male golden hamsters, 3 months of age, were injected with a 0.25% solution of 9, 10-dimethyl 1, 2-benzanthracene in acetone into the tongue at weekly intervals using a Panjet injector (Panjet^[○!R]: Wright, G. E.). Thirty hamsters surviving for six months or longer after initiation of the carcinogen injection were subjected to observation. By the llth week of experiment, the lingual mucosa became slightly hypertrophic and whitish in patches. Around the 24th week, nearly 80% of the animals were found to have formation of nodules in the lingual mucosa. After the 35th week of treatment the nodules grew in size of showed a papillary growth in occasinal animals. Histopathologically, there were seen dysplasia (11 animals), dysplasia with epithelial down growth (7 animals), papilloma (7 animals), carcinoma (3 animals), hemangioma (1 animal), neurilemmoma (1 animal).journal articl

    Efficient (R)-3-hydroxybutyrate production using acetyl CoA-regenerating pathway catalyzed by coenzyme A transferase

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    (R)-3-hydroxybutyrate [(R)-3HB] is a useful precursor in the synthesis of value-added chiral compounds such as antibiotics and vitamins. Typically, (R)-3HB has been microbially produced from sugars via modified (R)-3HB-polymer-synthesizing pathways in which acetyl-CoA is converted into (R)-3-hydroxybutyryl-coenzyme A [(R)-3HB-CoA] by β-ketothiolase (PhaA) and acetoacetyl-CoA reductase (PhaB). (R)-3HB-CoA is hydrolyzed into (R)-3HB by modifying enzymes or undergoes degradation of the polymerized product. In the present study, we constructed a new (R)-3HB-generating pathway from glucose by using propionyl-CoA transferase (PCT). This pathway was designed to excrete (R)-3HB by means of a PCT-catalyzed reaction coupled with regeneration of acetyl-CoA, the starting substance for synthesizing (R)-3HB-CoA. Considering the equilibrium reaction of PCT, the PCT-catalyzed (R)-3HB production would be expected to be facilitated by the addition of acetate since it acts as an acceptor of CoA. As expected, the engineered Escherichia coli harboring the phaAB and pct genes produced 1.0 g L^[-1] (R)-3HB from glucose, and with the addition of acetate into the medium, the concentration was increased up to 5.2 g L^[-1], with a productivity of 0.22 g L^[-1] h^[-1]. The effectiveness of the extracellularly added acetate was evaluated by monitoring the conversion of 13C carbonyl carbon labeled acetate into (R)-3HB using gas chromatography/mass spectrometry. The enantiopurity of (R)-3HB was determined to be 99.2% using chiral liquid chromatography. These results demonstrate that the PCT pathway achieved a rapid co-conversion of glucose and acetate into (R)-3HB

    Positively curved complex submanifolds immersed in a complex space form

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    The author gives the partial solution for the conjecture; a Kaehler submanifold in a complex space form of constant holomorphic sectional curvature 1 is totally geodesic if ever its holomorphic sectional curvature is greater than 1 2 \frac {1}{2} .</p
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