5,135 research outputs found
Culture Now: The Italian Avant-Garde: 1968-1976: Carlo Caldini, Martino Gamper in Conversation with Catharine Rossi and Alex Coles
No full textTo launch the first volume of EP, The Italian Avant-Garde: 1968-1976 (Sternberg Press, 2013), the architect Carlo Caldini and the furniture designer Martino Gamper discuss the legacy of the radical Italian avant-garde with the book’s editors, Alex Coles and Catharine Rossi.
Carlo Caldini is a Florence-based architect, and was co-founder (with Giorgio Birelli, Fabrizio Fiumi, and Paolo Galli) of Gruppo 9999. For EP, Carlo Caldini describes how the Space Electronic discotheque devised by Gruppo 9999 in the 1970s served as a progressive multimedia environment that nurtured the convergence of art, music, design, theater, and architecture in Florence.
Martino Gamper is a London-based furniture designer. For EP, Gamper talks with Michelangelo Pistoletto on the importance of Arte Povera as a form of socially engaged practice. Recent projects by Gamper include Monacopolis at The Nouveau Musée National de Monaco and the Postmundus Chair for Nilufar in Milan
Giovanni Bernardo De Rossi e la letteratura araba
No full textAlbeit mainly a Hebraist, De Rossi also developed an interest in other Semitic languages, in particular Arabic and Syriac. Leaving aside his first, naïve experiments, inspired by an outdated Renaissance polyglotism, his main contribution to Arabic studies consists in a Dizionario storico (‘Historical Dictionary’) in which he presented his Italian readership with a clever, smart, and updated tool to navigate medieval Arabic literature. The Dictionary stands out for De Rossi’s appreciation of the Qur’an’s aesthetic dimension, a result of his life-long intimacy with the pages of the Old Testament. In addition, he is the author of a dissertation in which he demonstrated the existence of the Paganini edition of the Qur’an, which at his time was dismissed as a baseless legend
Annabella Rossi e la fotografia. Vent'anni di ricerca visiva in Salento e in Campania.
No full textRaccolta di saggi sull'opera dell'antropologa Annabella Rossi nel panorama scientifico degli studi demoetnoantropologici italiani, con particolare riferimento alla figura di Ernesto de Martino
Athens and Alexandria. Paolo Rossi between Magic, Science, and the Irrational
No full textQuesto saggio esamina l’evoluzione del pensiero e delle polemiche dello storico delle idee Paolo Rossi (1923–2012) a proposito di varie correnti culturali antimoderne, irrazionaliste e primitiviste del ventesimo secolo, collocandole all’interno del suo percorso intellettuale. Queste prese di posizione si intrecciano con i suoi studi sull’interazione tra magia e scienza e tra magia e modernità, con il suo rapporto con il marxismo, con le sue reazioni ai movimenti controculturali degli anni Sessanta e Settanta, e con il suo debito e le sue divergenze intellettuali rispetto a maestri e figure di riferimento come Eugenio Garin, Antonio Banfi, Ernesto de Martino e Frances A. Yates. L’analisi metterà in luce un processo di approfondimento, rivalutazione e “drammatizzazione” della nozione di magia, accompagnato dalla convinzione crescente dell’importanza di rinnovare costantemente l’impegno – consolidatosi all’alba della modernità – verso la razionalità e la scienza e dalla crescente preoccupazione di fronte a correnti culturali e politiche tendenti a divergere da questo orientamento.In this essay, I explore the evolution of historian of ideas Paolo Rossi’s (1923–2012) views and polemical stances toward various twentieth-century antimodern, irrationalist, and primitivist cultural currents, situating them within his broader intellectual journey. I examine how these positions connect to his studies on the interplay between magic and science, as well as magic and modernity; his engagement with Marxism; his responses to the countercultural movements of the 1960s and 1970s; and his intellectual debts and departures from mentors and influences such as Eugenio Garin, Antonio Banfi, Ernesto de Martino, and Frances A. Yates. This exploration reveals a process of deepening, re-evaluation, and “dramatization” of the notion of magic, alongside Rossi’s growing conviction of the need to continually renew the commitment to rationality and science established at the dawn of modernity, and his mounting concern over cultural and political trends that seem to diverge from this path
An Architecture for a Mobility Recommender System in Smart Cities
No full textTo date, there is a wide availability of academic and commercial ICT proposals to improve urban mobility. Nevertheless, in the literature, there is still a lack of suitable solutions for door-to-door routing supporting users from their origins to destinations and including the suggestion on where to park. On the other hand, in an Internet-of-Things (IoT) scenario, a lot of novel information sources could be exploited to compute more efficient mobility solutions to be proposed to the user. As an example, parking availability data could be easily collected and exploited to provide multimodal routes (i.e. routes with at least two different means of transportation) that include suggestions on where to park and how to reach the final destination. In this paper, we describe a distributed IoT architecture towards the definition of a Mobility Recommender System. In particular, we focus on a car-based multimodality, where the user always starts a trip with his/her private vehicle, but he/she can also leave the car in Park-and-Ride infrastructures and reach the destination with public transportation. This type of routing on a wider search area will result to be more costly, and thus, it will particularly benefit from a parallel computational architectural solution
STUDIES ON ROLE OF HAEMODYNAMIC AND AUTONOMOUS NERVOUS SYSTEM CHANGES IN PATIENTS WITH OBSTRUCTIVE SLEEP APNOEA
No full textObstructive sleep apnea syndrome (OSAS) is a well established risk factor for
hypertension and is associated with an enhanced sympathetic activity. In this series of
studies we described the pathophysiological changes of blood pressure and autonomous
nervous system activity in patients with OSAS.
We demonstrated that CPAP can modulate the autonomous nervous activity by reducing
the sympathetic discharge as seen by a reduction of blood pressure variability.
In a cohort of 78 patients (76.9%male, 49%hypertensive) a 2 week autoset-CPAP
treatment determined a reduction of systolic BPV (5.3±4.9 vs 4.2±3.4 mmHg, p=0.047)
and pulse rate (78.0±14.5 vs 75.5±15.8 bpm, p=0.032).
An effect on blood pressure, pulse rate and blood pressure variability depends also on
CPAP adherence and, particularly in obese subjects, on pressure's loading effect on the
respiratory system. We studied 16 patients (13males, 47(10)years, BMI 38.5(5.8)kg/m2).
Blood pressure was measured continuously with a Finapres device at increasing CPAP
pressure levels. BP and BPV increased with incremental CPAP (systolic BP r=0.960,
p<0.001, diastolic BP r=0.961, p<0.001; systolic BPV r=0.662,p=0.026; diastolic BPV
r=0.886,p<0.001) and abdominal muscles activity, a surrogate marker of neuro respiratory
drive, correlated with both systolic (r=0.464,p=0.032) and diastolic BP (r=0.747,p=0.009).
As the activity of the autonomous nervous system is mediated by the catecholaminergic
system we hypothesized that the activity of Catechol-O-methyltransferase (COMT), one of
the major mammalian enzymes involved in the metabolic degradation of catecholamines,
measured during drug induced sleep endoscopy (DISE), was altered during intermittent
hypoxia in patients with OSAS.
We recruited 6 patients with OSAS who underwent DISE. During the procedure 7 blood
samples were drown for the analysis of COMT activity and catecholamines concentration
before, during and after an obstructive event. COMT analysis showed an increase of the
enzyme activity after sedation. This was more marked when propofol-induced central
apnea occurred compared to baseline (181.2 (12.8) pmol/min/mg vs 99.4 (11.1)
pmol/min/mg, p<0.05).
In this preliminary analysis we showed that the catecholaminergic system is stimulated
during DISE after apneic events. This might be due to an altered activity of COMT during
hypoxia therefore suggesting a novel pathophysiological pathway responsible of
hypertension in patients with OSAS
Interplay between uropathogenic Escherichia coli and bladder cells and new strategies to counteract bacterial persistence
No full textUrinary tract infections (UTIs) are the most frequent community and hospital-acquired infections. Uropathogenic Escherichia coli (UPEC) is the major causative agent of UTIs. The high level of recurrences, in which a single bacterial strain causes two or more consecutive UTIs, strongly suggests a reservoir within host. UPEC strains can invade epithelial cells of the urinary tract and replicate to form intracellular bacterial communities (IBCs) with biofilm-like properties, and may persist acting as quiescent intracellular bacterial reservoirs (QIRs). The formation of these structures represents a key event in the development of recurrences and is associate with the failure of conventional antibiotic therapies. The most crucial factor for the persistence of UTIs is the biofilm formation ability of UPEC, which protects them against harmful conditions, antimicrobial agents, and the host's immune system. Nanotechnology has been presented as a promising approach to enhance the activity of antimicrobial agents. The use of drug-delivery systems has been hypothesized for the controlled and localized release of drugs even in the case of multi-resistant bacteria and in the fight against biofilm. In order to identify bacterial characteristics possibly associated with recurrence of the infection, in this study UPEC strains, isolated from patients with recurrent UTIs, were sequenced, phenotypically and genotypically characterized, and assayed for invasion and survival ability in cell models. To explore new strategies able to induce bacterial clearance, the activity of niosomes (Nio) loaded with gentamicin (GM) was evaluated against intracellular bacteria and Nio, loaded with ciprofloxacin (CIP), was assayed for the capacity to inhibit biofilm formation. UPEC collected from patients suffering from recurrent UTIs and reference strains were used. The whole genome was performed on Illumina platform. Profiles relative to resistance genes, virulence factors, and multilocus sequence typing were determined by querying genomes against dedicated databases. The isolates were phenotypically characterized and assayed to adhere, invade, and persist in bladder cells (T-24 ATCC HTB-4) by gentamicin protection assay. ROS accumulation and interleukins production in T24 cells after UPEC infection, were detected. Empty and antibiotics loaded Nio were prepared and were characterized in term of stability and drug entrapment efficiency. To evaluate potential antiinvasive activity, non-cytotoxic and non-bactericidal concentrations of GM-Nio were added during the UPEC infection in the bladder. Furthermore, to verify the effect of CIP-Nio on biofilm production, bacterial strains were treated with niosomal preparations for 24 h. Ultrastructural biofilm modifications were visualized by Scanning Electron Microscopy (SEM). Genotypic characterization of the strains evidenced an heterogenous virulence factor profile. UPEC strains were moderate or strong biofilm producers, non-haemolytic and belonged to phylogroup D and B2. UPEC strains were able to efficiently adhere and invade, but not survive inside T24 cells. UPEC infection promoted the production of ROS but not all strains were able to induce interleukin production in bladder cells. Nio showed nanometric dimensions and a good stability profile and when loaded with antibiotics, significantly inhibited bacteria viability. Antibiotic delivered by Nio decreased UPEC invasion into bladder cells and efficiently inhibit the biofilm formation. UPEC genome is a mosaic continuum and no single feature can be used to differentiate strains. Similarly, no virulence factor alone is sufficient to cause disease. The complex interplay between bacterial infection capabilities, treatment success and host factors are likely to determine recurrence rather than specific genetic characteristics of the E. coli bacteria itself. Further studies exploring host-pathogen relationships and impact of QIR formation with organoid models in RUTI pathogenesis should be performed to contribute to translation of these results into innovative treatments
Faust Rossi
No full textFrom the video archives of the Cornell Law School Heritage Project. The interviewer is Peter W. Martin; the videographer, Michael d’Estries. This video covers Faust Rossi’s reflections on his career as a law professor. A 1960 graduate of Cornell Law School, Rossi began his legal career as a trial attorney in the United States Department of Justice Honors Program. He subsequently became a litigation partner in a Rochester law firm, and joined the Cornell Law School Faculty in 1966. He retired in 2013.
Professor Rossi is the author of a text on expert witnesses and coauthor of the Handbook of New York Evidence. He was a national winner of the Roscoe Pound Jacobson Award for excellence in teaching Trial Advocacy. Professor Rossi was a recurring visiting professor at Central European University in Budapest and a regular faculty member in the Cornell Summer Institute of International and Comparative Law in Paris. He has also given hundreds of lectures to lawyers and judges in the United States and Europe.
Faust Rossi is Samuel S. Leibowitz Professor of Trial Techniques, Emeritus
S. Martino vede in sogno Gesú Cristo
No full textPostal que reproduce una pintura del año 1317 de Simone Martini. Pertenece a la serie de Historias de San Martino. Representa, según la leyenda, el sueño que cambiaría la vida del Santo, donde Jesús se le aparece rodeado de ángeles y cubierto con esa parte de la capa que le había dado a los pobres. Al despertar Martino encontraría intacta la prenda que se había dividido en dos días antesAl pie de la postal aparece el siguiente texto: Assisi (Umbría), Chiesa inferiore di S. Francesc
S. Martino esposto in Chiesa
No full textPostal que reproduce una pintura del año 1317 de Simone Martini. Pertenece a la serie de Historias de San Martino, donde alrededor del santo, muerto y tendido en el suelo, están los clérigos y los fieles que asisten al ritoAl pie de la postal aparece el siguiente texto: Assisi (Umbría), Chiesa inferiore di S. Francesc
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