305,156 research outputs found
[Molecular analysis of the gene of steroidogenic acute regulatory protein (StAR) in adrenal incidentaloma].
No full textThe steroidogenic acute regulatory protein (StAR) plays an essential role in steroidogenesis, facilitating cholesterol entry into the inner compartment of mitochondria. Mutations (either transitions or transversions) of StAR gene have been described as a cause of lethal forms of congenital lipoid adrenal hyperplasia. Adrenal incidentalomas are frequently discovered during radiologic examinations performed in patients with diagnosis for other diagnostic problems. Enzymatic defects along the steroidogenetic cascade are observed with high frequency in these patients. Aim of the present study was to asses the involvement of alteration of the StAR gene in incidentally discovered adrenal masses (incidentalomas). The mutational analysis of 32 incidentalomas demonstrated a "missense" mutation in exon five of the gene in one of the tumors analysed. This is the first evidence of an alteration of the StAR gene in adrenal incidentalomas
Ai Act, un testo lungo e complesso che svela le difficoltà a normare il futuro
No full textA fronte di una tecnologia in rapidissima evoluzione, il legislatore europeo ha prodotto un testo legislativo tortuoso e di difficilissima interpretazione. L’AI Act è modesto dal punto di vista della tecnica legislativa, ma forse, data la natura sfuggente dell’oggetto regalato, era difficile fare diversamente. Il rischio è che Big tech sia pronta, le Pmi n
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
La renina attiva (RA) nell'infarto acuto del miocardio (IMA). Effetto della sede della necrosi e della terapia trombolitica.
No full textDispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Puglia Regione Universitaria Project as Action Research
No full textIn order to explore the unreleased declination of the relationship between the urban and the university system, the contribution aims to analyze the “flagship projects” of the regional research “PUGLIA REGIONE UNIVERSITARIA. Studiare e vivere in città accoglienti e sostenibili” verifying the impacts on the regional territory, practices, and community.As an example of research action project, the “flagship projects” and their verification are configured as the “active” part of the research, able to produce real effects and tangible impacts on the territory, with the aim of producing positive changes on reality. They belong to the third phase of the research, the more operational one, as application proposals, small experiments, funded and implemented by the proposing institutions, based on the knowledge framework developed in the previous phases of the project and returning a first, tangible feedback on the territories involved.
The knowledge systematization of the “flagship projects” concluded, in progress and in the planning stage, could be useful for to extrapolate generalizable and replicable research action guidelines, new territorial policies and innovative choices in terms of right to university study
Intelligenza artificiale, il futuro è nelle mani Usa. L’Italia produce articoli accademici, ma non imprese
No full textDove si trova la frontiera dell’Ia e come piomba sulle economie? Dal 2016 sono state create più di 41.500 nuove imprese, oltre 21mila negli Stati Uniti. Bene India e Regno Unito, l’Europa insegu
Il peptide vasoattivo intestinale nell'infarto acuto del miocardio: effetti della sede della necrosi e della terapia fibrinolitica.
No full textAuthor, publisher and bookseller : a tripartite synergy in Nigerian book industry
No full textThis work is about the roles of Author, Publisher and Bookseller in Book development in
Nigeria. The paper started by delving into the history of Book Publishing in Nigeria after
which it proceeded by defining who an author, a publisher, and a bookseller is and
expatiated on the indispensable roles of these key actors in Nigerian Book Industry and in
the emerging Information Society. Furthermore, the various constraints to book
development were identified while the paper advised on how the Book Industry can be
further promoted in Nigeria. However, the paper concluded and made recommendations
on how the Book sector can help in enhancing scholarship in the country
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