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Involvement of neuropeptides in the regulation of growth, structure and function of the adrenal cortex
No full textCurrent data on the influence of
neuropeptides on the growth, structure and function of
cells comprising the hypothalamo-pituitaq-adrenal axis
were presented and discussed. The action of vasopressin,
oxytocin, neurotensin, bombesin, neuropeptide Y,
substance P and VTP have been evaluated.
The hypothesis has been introduced that in vivo effect
of some neuropeptides on the structure and function of
the adrenal cortex is mediated by vasopressin
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Compensatory adrenal growth in aldosterone-treated male and female hamsters
Full text linkThe aim of the study was to investigate the
compensatory adrenal growth in aldosterone-treated
male and female hamsters. Hemiadrenalectomised and
sham-operated animals were treated for 5 days with a
daily d-aldosterone dose of 25 pglanimal.
In both male and female aldosterone-treated hamsters
monoadrenalectomy did not change the relative
adrenal weight if compared with sham-operated groups.
The fasciculata zonae of monoadrenalectomised aldosterone-
treated males was larger and contained more
parenchyma1 cells than in appropriate control group.
There was no difference in the volume of adrenocortical
zones, average cell volume and in cell number between
sham-operated and unilaterally adrenalectomised females.
In vitro 3H-thymidine incorporation per adrenal was
markedly higher in monoadrenalectomised than in
sham-operated aldosterone-treated males while the
opposite was true for female hamsters.
Thus, the action of aldosterone on CAG in the
hamster seems to depend on sex, with no effect in males
and inhibitory action in females
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Neuromedins and their involvement in the regulation of growth, structure and function of the adrenal cortex
Full text linkCurrent data on the synthesis and the
mechanism of action of neuromedins on adrenal cortex
are presented. The localization of these biologicallyactive
peptides in all components of the hypothalamopituitary-
adrenal axis as well as their action on the
adrenal cortex both in vivo and in vitro suggest their
involvement in the regulation of growth, structure and
function of the adrenal cortex. Neuromedins may exert
both direct and indirect effect on the adrenal cortex.
Direct effect is proven by the stimulation of glucocorticoid
synthesis by adrenocortical cells in culture
(NMK, NML) while indirect effects may be mediated by
ACTH, vasopressin (aldosterone secretagogue effect)
and angiotensin (prompt proliferative response) or by
substances of medullary origin. The last mechanism of
action is well documented for NMU
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