1,720,975 research outputs found
Sensibilizzazione ai metalli delle protesi ortopediche: uno studio su 50 pazienti
No full textBackground: currently, about 5% of operations of prosthesis implantation fail, but only a small part of these failures can be attributed to allergic reactions that result in dermatosis such as eczemas, eritrodermia, urticaria and prurigo. Objective: to understand the relevance of the sensitization to the materials used in orthopedic prostheses and the kind of allergic reactions that they can cause. Materials and Methods: the study group consisted of 50 patients (20 women and 30 men), whose ages ranged from 12 to 76 (the average age was 52.26 and the median 59) and who were attending at hospital specialized in orthopedics. All the patients underwent patch tests for metals and orthopedic metals. Ten of them were tested also for SIDAPA (Italian Society of Allergological, Occupational and Environmental Dermatology) integrated standard series and nine for polylactic acid 10% in vaseline. Thirty patients were patch tested before the orthopedic operation and 20 patients were tested after. Results and discussion: fourteen patients tested positive to one or more substances: nickel (14), potassium dichromate (2), palladium (2), cobalt chloride (1) and tin (1). It is difficult to determine if the patients who tested positive after the operation were also positive before, or if they became positive after contact with the metals in the prosthesis. Their case histories did not indicate if they underwent patch-tests for these substances prior to their operations. Moreover, we can not predict if a patient who had a negative patch-test before the operation can develop sensitivity to some metals after the implantation of a prosthesis. Allergy to metals is rather frequent in the general population, and for this reason a patient who must receive a prosthesis can be sensitive before the intervention or they can develop an allergy over time. As a matter of fact the implanted alloy can cause sensitization in a time window ranging from a few days to some years. More and more patients should undergo these tests before being operated for the implantation of a prosthesis and not only when potential sensitization to metals is suspected or when dermatological or orthopedic complications occur
LES HUGUENOTS: OPÉRA EN CINQ ACTES, MUSIQUE DE M. MEYERBEER, PAROLES DE M. SCRIBE, DIVERTISSEMENTS DE M. TAGLIONI, DÉCORS DE MM. SÉCHAN, FEUCHÈRE, DIÉTERLE ET DESPLÉCHIN.
Full text linkTranscript of LES HUGUENOTS: OPÉRA EN CINQ ACTES, MUSIQUE DE M. MEYERBEER, PAROLES DE M. SCRIBE, DIVERTISSEMENTS DE M. TAGLIONI, DÉCORS DE MM. SÉCHAN, FEUCHÈRE, DIÉTERLE ET DESPLÉCHIN by Hector Berlioz, appearing in REVUE ET GAZETTE MUSICALE DE PARIS, 6 mars 1836, pp. 73-77. [NB Online title metadata supersedes in-file title metadata.
Effect of Efalizumab on neutrophil and monocyte functions in patients with psoriasis
Full text linkWe evaluated the effect of efalizumab on neutrophil and monocyte functions. The in vitro preincubation with efalizumab concentrations similar to those reached during in vivo therapy almost completely saturated CD11a binding sites without affecting the membrane expression of CD11b, CD128a or CD128b. There was a significant reduction in the chemotactic activity of the pre-treated cells toward three different chemo-attractants, whereas their phagocytic capacity and production of oxygen radicals remained unchanged. One month after the administration of efalizumab to five patients with psoriasis (T1) circulating neutrophil counts increased by 34% from pre-therapy (T0) with no change in the number of monocytes. In the same patients the CD11a binding sites on phagocytes were >90% saturated, and there was also a significant down-modulation on neutrophils (44% of T0) and monocytes (63% of T0). In line with in vitro results, efalizumab treatment caused a significant deficiency in the chemotactic properties of neutrophils and monocytes, but no changes in phagocytosis, oxidative burst, production of pro-inflammatory cytokines or the membrane expression of CD11b, CD128a and CD128b. Our findings suggest that neutrophils and monocytes may be among the targets of efalizumab activity in patients with psoriasis
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Gli strumenti del case management infermieristico
No full textCostruzione e attuazione dei percorsi clinico-assistenziali.
Definiszione di percorso diagnostico-terapeutico-assistenziale.
Costruzione e implementazione dei PDTA.
I principali requisiti per la costruzione di un PDTA.
Rappresentazione del PDTA.
I sistemi di valutazione e gli indicatori.
Gestione e diffusione del PDTA.
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L'educazione terapeutica.
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