1,721,016 research outputs found
No association of tumor necrosis factor-alpha gene polymorphism and COPD in Caucasian smokers and Japanese smokers.
No full textThe search for susceptibility genes of COPD [see comments]
No full textEnvironmental factors, such as cigarette smoking, outdoor and indoor pollution, and childhood respiratory infections, are believed to play a major role as risk factors for developing chronic obstructive pulmonary disease (COPD). The only confirmed genetic risk factor for COPD is the inherited deficiency of alpha 1-proteinase inhibitor. However, the evidence of familial clustering of lung function and COPD occurrence and the development of COPD among susceptible smokers, at variance with the so-called resistant smokers, would suggest that the weight of genetic risk factors is greater than recognized. In this paper the role of candidate genes for increasing the risk of COPD (such as alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, cystic fibrosis transmembrane conductance regulator, and others) is reviewed
Candida antarctica lipase B catalyzes the regioselective esterification of ecdysteroids at the C-2 OH
No full textImmobilized Candida antarctica lipase B (Novozym 435) catalyzes the regioselective acylation of 20R-hydroxyecdysone (1a) and its congeners 2a, 3a and 4a at the C-2 OH in high yield and purity. (C) 1997 Elsevier Science Ltd
Normal sweat chloride values do not exclude the diagnosis of cystic fibrosis [letter; comment]
No full text
Desmosine, a biomarker for COPD: old and in the way..
No full textthe role of desmosines as biomarkers of chronic obstructive pulmonary disease
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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