533 research outputs found
Poesia per l'infanzia nel sec. XIX
No full textLa ricerca si sofferma ad analizzare un settore poco esplorato della letteratura per ragazzi: la produzione poetica per l'infanzia in Italia nel corso del diciannovesimo secolo. L'analisi di libri del primo Novecento ha permesso di rintracciare una prima attenzione critico-letteraria in questo specifico settore. Ciò ha permesso di ritenere il poeta Giovanni Pascoli come l'autore che,in virtù della sua concezione poetica, dell'infanzia e delle sue competenze liriche, segnò la fine della tradizione poetica ottocentesca e nello stesso tempo diede vita alle nuove modalità ed esperienze poetiche tipiche del Novecento. Andando a ritroso nel tempo per cercare di datare il punto di partenza del cambiamento intervenuto nella poesia dell'800, si giunge ad affermare che non è possibile indicare un autore di primaria importanza, sebbene vi siano alcuni nomi più conosciuti e di indiscutibile valore rispetto ad altri. Infatti si è rivelato significativo cercare e studiare fonti letterarie come antologie scolastiche di letteratura italiana nelle quali compaiono allo stesso tempo scrittori, poeti ed educatori. Le antologie hanno rivelato informazioni attorno a opere poetiche, al contesto culturale, a ragioni, a tematiche e a relazioni di tipo editoriale, culturale ed istituzionale. L’analisi ha evidenziato alcune importanti piste di ricerca nel periodo compreso tra il 1839 e il 1888, ed ha inoltre riscontrato il contributo significativo offerto alla poesia per ragazzi da Luigi Sailer, un autore poco studiato, sebbene sia l’autore di un’opera straordinariamente ricca, L’Arpa della fanciullezza, che ha avuto grande successo in Italia sia nel diciannovesimo secolo sia nel ventesimo con numerose riedizioni.The research is about a special subject of young people's literature, which has not had enough attention so far, children's poetry in nineteenth century in Italy. The analysis of the early twentieth century books has outlined the beginning of the critical-historical way of children's literature. This has made it possible to conside the poet Giovanni Pascoli as the author who, due to his idea of poetry and of childhood and his lyrical skills, marked the end of the nineteenth century tradition, and at the same time opening new ways and experiences typical of the twentieth century.So it seemed to be constructive to research and to study literary resources like the Literature Anthologies, where writers, poets and educators were collected together. The analysis has indicated some important tracks of research in the period between the 1839 and 1888, and has also verified the contribution to children's poetry of Luigi Sailer, a writer less studied, but author of an extraordinarily rich work, L'arpa della fanciullezza, which had a great success in Italy in the nineteenth and twentieth century
BUDIDAYA SELADA LOLLO ROSSA (Lactuca sativa var. capitata L.) SECARA HIDROPONIK SISTEM NFT DENGAN MEDIA PAKIS
No full textBUDIDAYA SELADA LOLLO ROSSA (Lactuca sativa var. capitata L.) SECARA HIDROPONIK SISTEM NFT DENGAN M
[Intestinal mycobacterial infections in AIDS. Clinical course and treatment of infections caused by Mycobacterium avium, Mycobacterium kansasii, Mycobacterium genavense]
No full textDigestive apparatus is a common target of atypical mycobacteriosis in AIDS patients (at least 50% of patients with CD4+ lymphocytes < 50/mm3). We describe the clinical-histological features of two cases of Whipple-like syndrome likely caused by Mycobacterium avium (MAI) (study performed by light and electron microscopy), of one case of infection caused by two morphological variants of a MAI strain with a different sensitivity to antibiotics, of one case of M. kansasii infection and of two cases of M. genavense infection accompanied by sensitivity tests to antibiotics (as far as we know, these are the first described quantitative sensitivity tests of M. genavense to antibiotics). In conclusion, we discuss the present therapeutical outlines for M. kansasii and avium, together with the teramporary pharmacological options for M. genavense as suggested by antibiotic sensitivity tests performed on the strains isolated from the studied patients
Novel applications of long-established histochemical techniques to study nanoparticle-cell interactions at transmission electron microscopy
No full textAlcian blue staining has been used to visualise nanoparticles at transmission electron microscop
Turbulent kinetic energy redistribution in a gravity current interacting with an emergent cylinder
No full textGravity currents are flows driven by density gradients between two or more contacting fluids and play a key role in nature and industrial environments via global ocean circulations, climate variability and the distribution of airborne pollutants. In the present work, we study, experimentally, the changes induced by an emergent vertical PVC cylinder on the mean and turbulent flow fields of an unsteady bottom-generated lock release gravity current. Tests were carried out, with and without the cylinder, in refractive index matching conditions and instantaneous velocities were acquired with a Particle Image Velocimetry system. The mean velocity field, Reynolds stresses and terms of turbulent kinetic energy (TKE) budget for the currents head were presented and discussed. The results show that the adverse pressure gradient generated by the cylinder induces a uniform deceleration of the current head. Hence, there are no appreciable differences on the spatial distribution of the mean velocities in the current head, compared to the undisturbed current. On the other hand, the changes on the turbulent flow field are remarkable. The total diffusion of TKE decays in the inner part of the head while becoming stronger at the interface between the two fluids, as the current approaches the cylinder. This is associated to an increase of the diffusion term due to pressure fluctuations, that acts against diffusion due to velocity fluctuations and contributes to disrupt the transport of TKE from the interface between the fluids and the inner part of the current. As a result, in the presence of an obstacle, Reynolds stresses are suppressed in the inner part of the current head and enhanced at the interface
TRASCRITTOMICA COME FRAMEWORK NELLO STUDIO DI NUOVI BIOMARCATORI DI RESISTENZA A STRESS AMBIENTALI: L’ESPERIENZA DI LISTERIA MONOCYTOGENES
No full textListeria monocytogenes is an ubiquitous bacterium responsible of food contamination causing often severe consequences in immunocompromised or pregnant people. The infection is related to the consumption of ready-to-eat food but also fish, meat, dairy and vegetables. Most important, L. monocytogenes often exhibits persistence and resistant features.
In 2015 a severe outbreak occurred in central Italy causing several infected and death people. The responsible strain was identified in “headcheese” samples which, from the point of view of the bacteria, can be considered a stressor environment in terms of storage temperature, pH,
salt and concentration.
Using a transcriptomic approach, based on a differential expression study, we were able to identify key genes and protein modules responsible
of such a fitness. Although expensive and difficult to apply routinely, RNAseq analysis revealed its usefulness in functional characterization of
pathogens strains
Towards a Neural Network Model of the Attentional Blink
No full textOne of the most prominent experimental paradigms for investigating the deployment of attention over time is the Attentional Blink (AB). Although there is now a great deal known about it, computational modeling of the AB remains only lightly explored. This paper responds to this limitation by proposing a prototype neural network model of the blink. A central aspect of which is a realization of the concept of consolidation into working memory, which is at the heart of the majority of current explanations of the blink
Hyaluronic acid-based nanocomplexes as novel drug-nanocarriers to treat myotonic dystrophy
No full textHyaluronic acid-based nanocomplexes have been developpend as novel drug-nanocarriers to treat myotonic dystroph
Aquatic plants entrap different size of plastics in indoor flume experiments
No full textPlastics accumulate in the environment affecting biota and ecosystems. Although rivers are vectors of land-based plastics to the sea, macroplastics and microplastics in rivers are recently studied. Most studies focused on floating plastic transport to the sea through rivers considering only abiotic hydromorphological factors. In this view, among biotic factors, vegetation has recently been found to entrap plastics. Indeed, the role of vegetation is pivotal in affecting riverine plastic transport. While marine vegetation blocking plastics has been studied, research in freshwater ecosystems is neglected. Since hydrological factors have a pivotal role in riverine plastic transport and few is known on plant entrapment, the interaction between hydrological variables and plastic entrapment by vegetation has not yet been investigated. Given that the composition, transport, and fate of “submerged” plastics in the water column are neglected, we aimed at investigating the behaviour of plants in entrapping plastics within a specific laboratory flume tank. Specifically, we assessed whether (i) aquatic plants block different plastic sizes within the water column and (ii) different factors (e.g. water level, density of plants) affect plastic entrapment. Our results showed that, according to plant density, the higher the plant density the higher the entrapment of plastics by plants - independently of plastic size. Considering the water level, macro-, meso-, and microplastics were trapped similarly. Moreover, Potamogeton crispus blocked fewer microplastics compared with Myriophyllum spicatum. Our results might have impact as plants acted as temporary plastic trappers and can be used as tools for mitigating plastic pollution. Future research might investigate if this laboratory approach can be applied in field for recollecting plastics and consequently mitigating the problem. In conclusion, good management of plants in watercourses, canals, and rivers should be ideal for enhancing river functionality and ecosystem services for human well-being (i.e. the plastic entrapment service by plants)
Chitosan-Alginate Blended Nanoparticles as Carriers for the Transmucosal Delivery of Macromolecules
No full textNanoparticles intended for use in the transmucosal delivery of macromolecules were prepared by the ionic gelation of chitosan (CS) hydrochloride with pentasodium tripolyphosphate (TPP) and concomitant complexation with sodium alginate (ALG). The incorporation of a small proportion of ALG of increasing molecular weight (Mw; from 4 to 74 kDa) into the nanoparticles led to a monotonic increase in colloidal size from ∼260 to ∼525 nm.
This increase in size was regarded as a consequence of the formation of gradually more expanded structures. Insulin, taken as a model peptide, was associated to CS-TPP-ALG nanoparticles with efficiencies in the range of ∼41 to ∼52%, irrespective of the Mw of the ALG incorporated in the formulation. These CS-TPP-ALG nanoparticles
exhibited a capacity to enhance the systemic absorption of insulin after nasal administration to conscious rabbits. Interestingly, it was observed that the duration of the hypoglycaemic response was affected by the ALG’s Mw. Briefly, this work describes a new nanoparticulate composition of potential value for increasing nasal insulin absorption
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