2,104 research outputs found
Strongly Lech-independent ideals and Lech's conjecture
No full textWe introduce the notion of strongly Lech-independent ideals as a
generalization of Lech-independent ideals defined by Lech and Hanes, and use
this notion to derive inequalities on multiplicities of ideals. In particular
we prove that if is a flat local
extension of local rings with , the completion of is the
completion of a standard graded ring over a field with respect to the
homogeneous maximal ideal, and the completion of is the
completion of a homogeneous ideal, then .Comment: minor update
In memory of Professor Lech Wojtczak, researcher and person
No full textProfessor Lech Wojtczak spent his entire scientific life at the Nencki Institute of Experimental Biology PAS, where he worked since 1947. He is the author or co-author of two hundred scientific papers, promoted 15 doctors of science, was the Full Member of PAS and has been awarded with several prizes and honors. Among his students are three successive directors of the Nencki Institute, the authors of the present article. Scientific interests of Professor Lech Wojtczak were always dealing with bioenergectics, a discipline that he led in Poland and Eastern-Central Europe. In particular, his studies focused on the role of fatty acids and their derivatives on bioenergetics, on the regulatory role of surface potential of biomembranes on enzymatic and transport activities, on the regulatory role of calcium and magnesium in mitochondria, on the role of free oxigen radicals in bioenergetics, etc. Apart from being a great scientist, Lech Wojtczak was also a fantastic teacher, and an excellent scientific supervisor. Being well recognized in the world, he was placing members of his research group in foreign laboratories, as well as was sending tchem to courses and conferences. This was opening their minds to the world, and to other cultures, and allowed Lech Wojtczak to form from his collaborators the next generation of good scientists and future leaders. The list of the most important pupils of Professor Wojtczak is given in the article. Lech was also excellent in social contacts, and in creating a friendly atmosphere. Together with his wife Anna, they kept an open home, often inviting collaborators to parties that usually led to long scientific discussions. With the sudden death of Pofessor Lech Wojtczak Polish science suffered a great loss. This eminent researcher, the father of Polish bioenergetics, but also a warm and modest person, will be dearly missed
A REVIEW OF THE BOOK: PATRYK WAWRZYŃSKI, PREZYDENT LECH KACZYŃSKI. NARRACJE NIEDOKOŃCZONE [PRESIDENT LECH KACZYNSKI. THE UNFINISHED NARRATIVES], WYDAWNICTWO ADAM MARSZAŁEK, TORUŃ 2012
No full textWith these words of Mark Antony – as a motto – Patrick Wawrzyński could start his book. Published in 2012, the work is titled "President Lech Kaczynski. The unfinished narratives" (Prezydent Lech Kaczyński. Narracje niedokończone), and it is just such an attempt of doing justice to the tragically deceased president of the Republic of Poland. The author has undertaken the task of presenting the views of Lech Kaczynski as they actually were – separating them from incorrect interpretations and opinions attributed by other actors of the Polish political scene: his opponents as well as allies
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus.
No full textThe long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes. Both of these mechanisms are known to be involved in autoimmunity and autoimmune tissue injury, e.g. in systemic lupus erythematosus, but a contribution of PTX3 is hypothetical. To evaluate a potential immunoregulatory role of PTX3 in autoimmunity we crossed Ptx3-deficient mice with Fas-deficient (lpr) C57BL/6 (B6) mice with mild lupus-like autoimmunity. PTX3 was found to be increasingly expressed in kidneys and lungs of B6lpr along disease progression. Lack of PTX3 impaired the phagocytic uptake of apoptotic T cells into peritoneal macrophages and selectively expanded CD4/CD8 double negative T cells while other immune cell subsets and lupus autoantibody production remained unaffected. Lack of PTX3 also aggravated autoimmune lung disease, i.e. peribronchial and perivascular CD3+ T cell and macrophage infiltrates of B6lpr mice. In contrast, histomorphological and functional parameters of lupus nephritis remained unaffected by the Ptx3 genotype. Together, PTX3 specifically suppresses autoimmune lung disease that is associated with systemic lupus erythematosus. Vice versa, loss-of-function mutations in the Ptx3 gene might represent a genetic risk factor for pulmonary (but not renal) manifestations of systemic lupus or other autoimmune diseases
In one breath (Jednym tchem) performed at the Theatre of the Eighth Day
No full textThis text deals with the 1971 play Jednym tchem (In one breath), performed at the Theatre of the Eighth Day (Teatr Ósmego Dnia) and based on Stanisław Barańczak’s poem. Lech Raczak outlines the methods used in the play, the characters, way of presenting a poetic text and the music in the performance. The author uses fragments of performance records published in his previous book Szaleństwo i metoda. 48 tekstów o teatrze (Madness and method. 48 texts about theatre) (Wydawnictwo Miejskie Posnania, Poznań 2012).<br /
Lech Ratajski
No full textLech Ratajski was born on 26 April 1921, in Rawa Mazowiecka, in a teachers' family. In 1939 he obtained the school-leaving certificate in Łomża. During the II World War he worked as a teacher and a clerk. He was also a member of the Home Army (AK) and he took part in the sabotage actions for which in 1949 he was honoured with the Cross of Valour. After the war he studied at the Academy of Fine Arts in Cracow for two years. In 1950 he graduated of the Jagiellonian University in Cracow with a degree in geography. As a student he collaborated with the popular monthly magazine „Poznaj Świat” (Know the World) for which he elaborated maps, designed covers, and wrote short notes. In 1950, accordingly to his interests, he took a post at the Department of Regional Geography within the Geographical Institute of the University of Warsaw. He wrote on the subject of the geographic names and in 1959 he was a co-author of the extensive specification comprising 20,000 geographical names. He was also the co-author of the wall economic charts of Poland and of the world, that were innovative in the Polish cartography of those days. He continuously collaborated with the magazine „Poznaj Świat” that was being published in Warsaw since the end of 1955 and he was its Editor-in-chief since 1968. He was the author of many articles and notes on the regional geography and of a book - a compendium of knowledge on Africa. The main field of his scientific interest was the thematic cartography, especially the economic maps and to this issue both his dissertations were related: the doctor's dissertation (1962) on the achievements of the Polish economic cartography in 20th century and the habilitation dissertation ( 1966) on industrial maps and their cartometric value. He devised the model of the cartographic methods of presentation, the model of cartographic generalisation, and the proposition of economic maps signs standardisation. Since 1968 he was the chairman of the Working Group and later of the Commission on Communication in Cartography at the International Cartographical Association (ICA). In the academic year 1971/1972 he lectured at the University of Edmonton and participated in the International Cartographical Association conference in Ottawa, at which he was elected the Vice-president of the Association. During his stay in Canada he prepared the textbook Methodology of the socioeconomic cartography that was published in 1973, and its second, updated edition was published in 1989. At the end of 1967 he was appointed the professorship at the Chair of Cartography where he introduced many didactic innovations - among others the free-hand drawing. In 1973 he employed dr W. Grygorenko (the future Chairman of the Chair) to teach computer cartography to the students. He tutored approximately 90 master's thesis, including 17 on the economic charts of the Polish voivodeships. In 1973- 1977 four employees of his Chair were promoted doctors. In 1973 Lech Ratajski obtained the title of a professor. He served several functions at the Polish Geographic Society, among others he was the President of the Commission of Cartography. In 1976 he was honoured with the medal of the Society. His bibliography comprises over 400 items including over 150 on cartography. He was the author of 30 portable and wall maps and approx. 600 annex maps to articles, books, and encyclopedias. Lech Ratajski died on 22 November 1977, in Warsaw
Die interglazialen Kalksinterbildungen bei Hurlach nördlich Landsberg am Lech
No full textVon Hurlach nördlich Landsberg a. Lech werden Sinterkalke mit vielfältiger Ausbildung beschrieben. Sie zeichnen sich durch humose Lagen und durch eine reiche Molluskenfauna aus (vgl. Beitrag Kovanda, i. ds. Bd.). Nach der geologischen Situation und aufgrund weiterer Ergebnisse (Palynologie, Malakologie, U/Th-Datierung) besitzen sie ein interglaziales Alter (Riß/Würm). Die Kalkabsätze sind heute isoliert, durch Seiten- und Tiefenerosion von den am östlichen Lechsteilhang austretenden Quellen abgeschnitten. Der Lech hat demzufolge hier in den letzten hunderttausend Jahren sein Steilufer bis zu 200 m weit nach E zurückverlegt.researc
Pressurized Van de Graaff electrostatic accelerator « Lech »
No full textThe Van de Graaff accelerator LECH is a completely home made machine. It was put in operation in 1961. Since its putting into operation the accelerator have passed several improvements and modifications. At present its main data are given in table I. Now the reconstruction of the accelerator is carried out. It involves reconstruction or replacement of the following units : the supporting insulating column, the high-voltage terminal, the accelerating tube, the charging belt drive mechanism, the ion source and the power supply system. As a result the acceleration voltage should increase to about 4.5 MV and the characteristic of the ion beam and energy stability should improve. The Van de Graaff accelerator LECH is mainly used for the basic research in nuclear physics and for application of nuclear research methods in other fields of physics and technology.L'accélérateur Van de Graff Lech a été complètement réalisé par le laboratoire et mis en service en 1961. Depuis cette date différentes améliorations furent amenées. Le tableau I donne les caractéristiques essentielles. Actuellement une reconstruction est en cours, changement de la colonne, du terminal, du tube, de la courroie, de la source d'ions et des alimentations. La tension pourra alors monter à 4,5 MV et les caractéristiques du faisceau et la stabilité de tension seront améliorées
Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction.
No full textInnate immune activation via IL-1R or Toll-like receptors (TLR) contibutes to acute kidney injury but its role in tissue remodeling during chronic kidney disease is unclear. SIGIRR is an inhibitor of TLR-induced cytokine and chemokine expression in intrarenal immune cells, therefore, we hypothesized that Sigirr-deficiency would aggravate postobstructive renal fibrosis. The expression of TLRs as well as endogenous TLR agonists increased within six days after UUO in obstructed compared to unobstructed kidneys while SIGIRR itself was downregulated by day 10. However, lack of SIGIRR did not affect the intrarenal mRNA expression of proinflammatory and profibrotic mediators as well as the numbers of intrarenal macrophages and T cells or morphometric markers of tubular atrophy and interstitial fibrosis. Because SIGIRR is known to block TLR/IL-1R signaling at the level of the intracellular adaptor molecule MyD88 UUO experiments were also performed in mice deficient for either MyD88, TLR2 or TLR9. After UUO there was no significant change of tubular interstitial damage and interstitial fibrosis in neither of these mice compared to wildtype counterparts. Additional in-vitro studies with CD90+ renal fibroblasts revealed that TLR agonists induce the expression of IL-6 and MCP-1/CCL2 but not of TGF-β, collagen-1α or smooth muscle actin. Together, postobstructive renal interstitial fibrosis and tubular atrophy develop independent of SIGIRR, TLR2, TLR9, and MyD88. These data argue against a significant role of these molecules in renal fibrosis
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