94,866 research outputs found

    James M. Cox portrait

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    Portrait of Governor James M. Cox who served three, two year terms as Governor from 1913-1915 and 1917-1921. In 1920 he was the Democratic candidate for President, but lost the election to fellow Ohioan Warren G. Harding

    Cox-Fiva-Smith-CPS-Replication – Supplemental material for Parties, Legislators, and the Origins of Proportional Representation

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    Supplemental material, Cox-Fiva-Smith-CPS-Replication for Parties, Legislators, and the Origins of Proportional Representation by Gary W. Cox, Jon H. Fiva and Daniel M. Smith in Comparative Political Studies</p

    [Letter from George M. Cox to T. N. Carswell - November 27, 1941]

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    A letter written to Mr. T. N. Carswell, Parramore Post No. 57, American Legion, Abilene, Texas, from George M. Cox, Executive Editor, The Mobile Press Register, Mobile, Alabama, dated November 27, 1941. George M. Cox defines Americanism

    Oral History Interview with Otis Cox, April 2, 2005

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    The National Museum of the Pacific War presents an oral interview with Otis M. Cox. Cox was born in Harlan, Kentucky on 10 May 1923. Soon after graduating from high school in 1941, he joined the US Army Air Corps. Upon completion of basic training at Shreveport, Louisiana he was sent to Ft. Logan, Colorado to attend a technical training school. He recalls various air bases to which he was assigned and of the various jobs he performed. During the course of his time in the service, he learned radio operator procedures through on the job training. After undergoing crew training, he was sent to India where he joined the 1st Troop Carrier Squadron. He flew 44 round trip flights over the Himalaya Mountains. He returned to the United States during November 1945 and was discharged the following month

    Selective COX-2 inhibitors and risk of myocardial infarction

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    Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids. Recently some coxibs, which were designed to exploit the advantageous effects of non- steroidal anti-inflammatory drugs while evading their side effects, have been reported to increase the risk of myocardial infarction and atherothrombotic events. This has led to the withdrawal of rofecoxib from global markets, and warnings have been issued by drug authorities about similar events during the use of celecoxib or valdecoxib/ parecoxib, bringing about questions of an inherent atherothrombotic risk of all coxibs and consequences that should be drawn by health care professionals. These questions need to be addressed in light of the known effects of selective inhibition of COX- 2 on the cardiovascular system. Although COX- 2, in contrast to the cyclooxygenase-1 ( COX- 1) isoform, is regarded as an inducible enzyme that only has a role in pathophysiological processes like pain and inflammation, experimental and clinical studies have shown that COX- 2 is constitutively expressed in tissues like the kidney or vascular endothelium, where it executes important physiological functions. COX- 2- dependent formation of prostanoids not only results in the mediation of pain or inflammatory signals but also in the maintenance of vascular integrity. Especially prostacyclin ( PGI(2)), which exerts vasodilatory and antiplatelet properties, is formed to a significant extent by COX- 2, and its levels are reduced to less than half of normal when COX- 2 is inhibited. This review outlines the rationale for the development of selective COX- 2 inhibitors and the pathophysiological consequences of selective inhibition of COX- 2 with special regard to vasoactive prostaglandins. It describes coxibs that are currently available, evaluates the current knowledge on the risk of atherothrombotic events associated with their intake and critically discusses the consequences that should be drawn from these insights. Copyright (C) 2005 S. Karger AG, Basel

    Samuel S. Cox portrait

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    Portrait of Samuel S. Cox, ca. 1890-1899. Cox strongly opposed slavery's expansion into new territory during the 1850s. As an Ohioan, he served in the United States House of Representatives from 1857 to 1865. Cox also served New York as a U.S. representative from 1869 to 1885 and from 1887 to 1889. He died in office in 1889. This cabinet card may have been created after his death as a memorial

    [Letter from Warren M. Cox to Dr. Meyer Bodansky - December 3, 1940]

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    Letter from Dr. Warren M. Cox, Jr. to Dr. Bodansky requesting at least 100 reprints of a paper that Dr. Bodansky published and advising that Dr. Bodansky's summary of the findings on maternal and fetal calcium levels in the Journal of Pediatrics be presented at the meeting of the American Pediatric Society or of the Pediatric Research Society. There is a handwritten post script from Dr. Warren M. Cox to Dr. Bodansky indicating they are sorry that Dr. Bodansky did not make it to Memphis
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