2,402 research outputs found
Gravity-flow dominated sedimentation on the Buda paleoslope (Hungary): Record of Late Eocene continental escape of the Bakony unit
No full textThe Upper Eocene sequence of the Buda Hills consists of fluvial and shallow marine conglomerates, sandstones, bioclastic shallow-water limestone, marlstone and pelagic Globigerina marl. The succession illustrates rapid, overall subsidence of the area, from terrestrial environments to bathyal depths. Sedimentation occurred on slopes situated on the flanks of synsedimentary basement antiforms. Vertical growth of antiforms caused progressive tilting of beds, layerparallel extension by boudinage and faulting, and induced redeposition by mass flow. Antiforms are localised in the dextral Budaörs shear zone and in the Buda
imbricate stack, which accommodated the dextral displacement. The latter is underlain by blind reverse faults probably merging into a detachment tault at shallow
depths. These structures were formed by WNW-ESE
oriented compression and NNE-SSW directed tension. The morphological expression of the imbricate stack is the SE-facing Buda slope.
The Bakony unit, while "escaping" from the Alps, was bordered by a northern sinistral and a southern dextral
shear zone. Synsedimentary tectonics in the Buda Hills demonstrates the style of deformation inside the escaping block, close to the southern border zone. Tectonically controlled sedimentation suggests that escape tectonics was active as early as Late Eocene time
Buda y Jesús
No full textEl estilo de vida propio de Buda y el de Jesús de Nazaret tienen rasgos comunes dentro de su aparente diversidad. Las relaciones entre el budismo y el cristianismo, vistas desde la óptica de los fundadores, es el tema del presente artículo. Se pretende analizar la experiencia subyacente a ambas religiones, indicando los puntos comunes y la necesidad de un diálogo entre los mismos "Buda y Jesús". El autor tiende a considerar a Buda, desde una óptica cristiana, como el "Juan Bautista" de Jesús para el mundo oriental
High Resolution Stratigraphy and Facies Architecture of Buda Formation in Central Texas
No full textThe Upper Cretaceous Buda Formation in central Texas is overlain by Eagle Ford group (or False Buda unit locally), and overlying the Del Rio Formation (Grayson Formation). The Buda Formation outcrop exposes from west Texas to the Dallas-Forth Worth area, and extends continuously into subsurface in central Texas. This study focuses on subsurface stratigraphy of the Buda Formation based on core analysis and outcrop descriptions to determine the regional distribution of depositional environment of the Buda Formation in central Texas.
Three facies (from deep to shallow) are interpreted from core to outcrops: foraminfera mudstone, skeletal wackestone/packstone, and massive mudstone. Outcrops are mainly composed of skeletal wackestone with massive mudstone, whilst cores are dominated by globigerinid mudstone and skeletal wackestone/packstone. Both outcrops and cores are extremely burrow mottled. The abundance of bioturbation and benthic forams across the depositional profile suggests deposition occurred along a well-oxygenated, low relief ramp.
2D strike and dip cross sections constrained by cores indicate that the thickness of the Buda Formation varies significantly from 20 to 100 feet through central Texas. Considerable thickening of the Buda Formation within the trough between Edwards and Sligo paleo shelf margins occurs in south Wilson, north Karnes and Gonzales counties of central Texas. The dramatic variations of the Buda Formation thickness along the dip direction are consistent with filling differential accommodation space across the paleotopographic profile of the pre-existing Lower Cretaceous reef trend. Depositional pattern shown on cross-section indicates possible transgression sequence followed by Eagle Ford transgression.
Typical reversed ���J��� pattern shows the relationship of ��^13CvPDB and ��^18OvPDB from core samples indicating the Buda Formation definitely being altered under meteoric conditions during diagenetic process. Cathodoluminescence results indicate two diagenetic events occurred in Buda Formation from early marine cementation to burial diagenesis under marine-meteoric mixing water conditions based on two luminesces color stages from dull to bright orange.
The False Buda unit (locally overlying the Buda Formation in central Texas) is quite similar to Maness shale (equally to lower Eagle Ford group in south Texas) composed of low Ca but high Si, Al, K based on geochemical analysis. Large negative excursion event is shown around the Lower Eagle Ford-False Buda contact, which possibly indicates that subaerial exposure or marine erosion occurred during sedimentation
Fludarabine, Bortezomib, Myocet and rituximab chemotherapy in relapsed and refractory mantle cell lymphoma
No full textAbstract
Based on the hypothesis that bortezomib may potentiate fludarabine activity by inhibiting DNA repair, we designed a phase I trial using this combination with rituximab in patients with relapsed and refractory indolent and mantle cell non-Hodgkin lymphoma. Twenty-four patients were enrolled. Non-Hodgkin lymphoma subtypes included 12 patients with follicular lymphoma, four with marginal zone lymphoma, three with lymphoplasmacytic lymphoma, three with mantle cell lymphoma and two with small lymphocytic/chronic lymphocytic leukaemia. Fludarabine and bortezomib were escalated in cohorts of three patients. Rituximab was added to the maximum tolerated dose of fludarabine and bortezomib and added significant dose-limiting myelosuppression. The maximum tolerated dose was fludarabine 25 mg/m(2) on days 1-3, bortezomib 1.3 mg/m(2) on days 1, 4, 8, 11, with rituximab 375 mg/m(2) on day 1 administered every 21 d. Clinical responses were observed in 11 patients, five of whom were refractory to their most recent treatment regimen. Six additional patients had stable disease for a median of 10 months (range 4-30+). Cumulative myelosuppression and neuropathy was observed. The combination of fludarabine, bortezomib, and rituximab appears to be an active regimen with manageable toxicity for relapsed NHL
Buda-Lund hydro model and the elliptic flow at RHIC
No full textThe ellipsoidally symmetric Buda-Lund hydrodynamic model describes naturally the transverse momentum and the pseudorapidity dependence of the elliptic flow in Au+Au collisions at roots(NN) = 130 and 200 GeV. The result confirms the indication of quark deconfinement in Au+Au collisions at RHIC, obtained from Buda-Lund hydro model fits to combined spectra and HBT radii of BRAHMS, PHOBOS, PHENIX and STAR
Did I turn off the gas? Reality monitoring of everyday actions.
No full textFailing to remember whether we performed, or merely imagined performing, an everyday action can occasionally be inconvenient but, in some circumstances, can have potentially dangerous consequences. In this fMRI study, we investigated brain activity patterns, and objective and subjective behavioral measures, associated with recollecting such everyday actions. We used an ecologically-valid 'reality monitoring' paradigm in which participants performed, or imagined performing, specified actions with real objects drawn from one of two boxes. Lateral brain areas, including prefrontal cortex, were active when participants recollected both the actions that had been associated with objects and the locations from which they had been drawn, consistent with a general role in source recollection. By contrast, medial prefrontal and motor regions made more specific contributions, with supplementary motor cortex activity associated with recollection decisions about actions but not locations, and medial prefrontal cortex exhibiting greater activity when remembering performed rather than imagined actions. The results support a theoretical interpretation of reality monitoring that entails the fine-grained discrimination between multiple forms of internally- and externally-generated information
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