2,938 research outputs found
'Als de marktvraag naar schone bollen groeit, ben ik er klaar voor'
No full textIn een wereld waarin steeds meer aandacht is voor duurzaamheid, zal de vraag naar duurzaam of biologisch geteelde bollen alleen maar groeien. Dat is in elk geval het idee van de kwekers die op dit terrein aan het pionieren zijn. Want er valt veel te leren. Ondanks alle hobbels en kuilen die zij op hun pad tegenkomen, houden de kwekers vol, want: ‘Ik wil gezonde bollen telen.
Voltage quality monitoring, dips classification and responsibility sharing
No full textCEER and EURELECTRIC cooperation in the field
of quality of electricity supply, involving joint meetings and the
participation at the relevant CENELEC Technical Committee,
contributed to the results attained in the recent publication of the
EN 50160:2010 edition that includes a new voltage dips
classification table allowing harmonisation at European level on
voltage dips data collection. The generalisation of voltage quality
monitoring data publication all over Europe will allow the
definition of responsibility sharing between the different involved
stakeholders and the evolution of voltage quality regulation
applied at national level. Examples from Sweden and Italy are
briefly presented in this paper
It takes three to tango: the geometry of workplace mediation
No full textDuring recent years, there has been a growing interest in the field of employment relations in the use of mediation as an important way to resolve disputes in the workplace. This interest reflects the changing nature of ‘the social contract’ between employer and employees which focuses more on individualised labor relations, or i-deals. This is in line with the shift from formal and confrontational dispute resolution to more ‘interest-based’ conflict management systems in organizations in which primary attention is paid to underlying interests, needs and wishes of parties instead of collective rules. In this discussion chapter, we address first the developments in the field of workplace mediation and its relation to the changing nature of employment relations. In doing so, we refer to social exchange theory. Second, in order to assess the effectiveness of mediation, we build further on the “geometry of workplace mediation’’ already introduced in the first chapter of this handbook. The geometry resulting from the combination of the 3 dimensions (regulations, roles and relations) as described by the 3r-model is well situated as a conflict management and resolution system for the promotion of efficiency, equity and voice standards, and provides a contingent approach to the design of optimal and effective workplace mediation systems depending on the specific society, industry and organization.keywordsindustrial relationdispute resolutionconflict managementemployment relationdispute resolution alternativethese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves
Promoting effective workplace mediation
No full textInitial research on workplace mediation focused on styles and tactics a mediator should use to conduct a successful mediation. Attention has shifted to the question which strategies and tactics are most appropriate and effective given certain mediation situations, organizational circumstances, and dispute as well as disputant characteristics. In response to this, we developed a model that helps mediators to get insight in the characteristics of the environment that affects the mediation process, and to choose the most appropriate mediation interventions: the 3-r model of workplace mediation. This model refers to three dimensions that are important to consider in case of mediation: regulations, roles and relations. Different combinations of these three dimensions determine together the mediation features and the mediation outcomes. In this introductory chapter, the 3-r model of workplace mediation is explained and used to structure the chapters of the handbook. We focus on four main themes: (i) the mediation process, (ii) the context of workplace mediation, (iii) mediation and other third party roles and (iv) new developments.keywordsconflict managementmediation processalternative dispute resolutionworkplace bullyonline dispute resolutionthese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves
The autonomic nervous system in septic shock and its role as a future therapeutic target: a narrative review
No full textThe autonomic nervous system (ANS) regulates the cardiovascular system. A growing body of experimental and clinical evidence confirms significant dysfunction of this regulation during sepsis and septic shock. Clinical guidelines do not currently include any evaluation of ANS function during the resuscitation phase of septic shock despite the fact that the severity and persistence of ANS dysfunction are correlated with worse clinical outcomes. In the critical care setting, the clinical use of ANS-related hemodynamic indices is currently limited to preliminary investigations trying to predict and anticipate imminent clinical deterioration. In this review, we discuss the evidence supporting the concept that, in septic shock, restoration of ANS-mediated control of the cardiovascular system or alleviation of the clinical consequences induced by its dysfunction (e.g., excessive tachycardia, etc.), may be an important therapeutic goal, in combination with traditional resuscitation targets. Recent studies, which have used standard and advanced monitoring methods and mathematical models to investigate the ANS-mediated mechanisms of physiological regulation, have shown the feasibility and importance of monitoring ANS hemodynamic indices at the bedside, based on the acquisition of simple signals, such as heart rate and arterial blood pressure fluctuations. During the early phase of septic shock, experimental and/or clinical studies have shown the efficacy of negative-chronotropic agents (i.e., beta-blockers or ivabradine) in controlling persistent tachycardia despite adequate resuscitation. Central α-2 agonists have been shown to prevent peripheral adrenergic receptor desensitization by reducing catecholamine exposure. Whether these new therapeutic approaches can safely improve clinical outcomes remains to be confirmed in larger clinical trials. New technological solutions are now available to non-invasively modulate ANS outflow, such as transcutaneous vagal stimulation, with initial pre-clinical studies showing promising results and paving the way for ANS modulation to be considered as a new potential therapeutic target in patients with septic shock
Nitric oxide metabolism and hypoxic vasodilation
No full textINTRODUCTION. When arterial O2 content is reduced, reflex increases in blood flow occur
in an attempt to restore local O2 supply. This "hypoxic vasodilation" involves excess levels of nitric oxide (NO). However, controversy persists as to whether this is due to increased NO production by NO synthase, increased NO generation from nitrite (by nitrite reductase), or
through decreased NO metabolism by mitochondria.
OBJECTIVES. To confirm that vasodilation is a NO-mediated response to tissue hypoxia,
and to clarify mechanisms underlying this reflex.
METHODS. Under isoflurane anaesthesia, spontaneously-breathing fluid-resuscitated male Wistar rats (250–350 g) underwent intravascular cannulation for blood pressure (ABP) monitoring, blood gas analysis, and fluid/drug administration. Tissue PO2 (tPO2) was determined using a luminescence probe placed in thigh muscle. Animals were allowed to stabilize for 300 after surgery and were then randomized to receive either room air or a hypoxic mixture (FiO2 0.125). In separate experiments both groups received, alone or in combination, a 100 continuous infusion of the non-selective NOS-inhibitor SEITU (1.5 mg/kg/min), the nitritedonor
NaNO2 (0.25 mg/kg/min), or vehicle. Data shown as mean ± SD. Statistics were
performed using 2-way repeated-measurement ANOVA and post-hoc Tukey’s test.
RESULTS. Hypoxia significantly reduced PaO2 from a baseline level of 10.8 ± 1.1 to
6.2 ± 2.8 kPa (p\0.001); tPO2 dropped from 6.1 ± 0.8 to 3.0 ± 0.4 kPa (p\0.001). None
of the interventions modified PaO2 or tPO2 levels.CONCLUSIONS. Hypoxic vasodilation is, at least in part, an NO-mediated process: hypoxia reduced ABP and tPO2, blunted the hypertensive effect of SEITU and accentuated the hypotensive effect of nitrite. We argue that, in hypoxia, NO derives only partially from NOS synthesis. Further insights into NO metabolism in hypoxia may help to better understanding mechanisms underlying haemodynamic adaptations.
REFERENCES. 1. Blitzer ML, et al. Am J Physiol (Heart Circ Physiol) 1996;271:H1182–5.
2. Allen JD, et al. Br J Pharmacol 2009;158:1653–4.
GRANT ACKNOWLEDGMENT. MU was supported by a Physiology Award of the Accademia
Nazionale dei Lincei (Roma)/Royal Society (London)
An unsupervised learning schema for seeking patterns in rms voltage variations at the sub-10-minute time scale
No full textThis paper proposes an unsupervised learning schema for seeking the patterns in rms voltage variations at the time scale between 1 s and 10 min, a rarely considered time scale in studies but could be relevant for incorrect operation of end-user equipment. The proposed framework employs a Kernel Principal Component Analysis (KPCA) followed by a k-means clustering. The schema is applied on 10-min time series with a 1-s time resolution obtained from 44 different periods of a location south of Sweden. Then, ten patterns are obtained by reconstructing the 10-min time series from each cluster center. The results of the proposed schema show a good separation of cluster centers. Moreover, some statistical power-quality indices are applied to the whole dataset, showing voltage variation between (0.5–3) V over a 10-min window. Obtaining the most suitable indices and applying them to the ten obtained cluster centers and their belonging time series shows that the existing statistical indices may not be enough to show a complete picture of the sub-10 min actual variations. This outcome shows the necessity of extracting 10-min patterns through our proposed schema besides the existing statistics to quantify the voltage variations, levels, and patterns together. Findings of this paper are: Not forgetting the sub-10-min time scale; The necessity of employing both statistics and the proposed schema; Extraction of ten typical patterns; The need for the statistics and patterns that are justified as changes in equipment connected to the grid; and compressing a huge amount of data from power-quality monitoring. The proposed schema is applied to a much less understood phenomena/disturbance type so that this work will result in general knowledge beyond the specific case study
The United Nations Environmental Council: Towards a sustainable future!
No full textChair of Materialisation and Design DevelopmentArchitectureArchitectur
TBV kan nog laat in seizoen bollen besmetten
No full textUit dit onderzoek is gebleken dat planten die eerder in het seizoen worden geïnfecteerd, bol len geven met een hoger percentage TBV Plan ten die eenmalig een week voor het rooien wor den besmet, geven bijna geen zieke bollen. Bij infectie twee weken en langer voor het rooien loopt het percentage zieke bollen sterk op. Ook worden klisters later ziek dan de hoofdbol. Infec tie vindt blijkbaar plaats vanuit de plant via de hoofdbol naar de klisters. ln de praktijk vindt inl'e tiegedurende hei hele seizo n pla11 door pas r nde, vliegende blad luizen. In de praktijk i du ook ni t va 1 te tel len wanneer planten voor hel er t geïnfecteerd raken. Vrijwel zeker gebeurt dat ook al vroeg in het seizoen. In dat geval is er dus geen spra ke van een lager percentage virus in de kleine maten. De resultaten hebben betrekking op het onder zoek in een cultivar ('Strong Gold') en van een seizoen (2013-2014). Om beter gefundeerde conclusies te kunnen trekken is vervolgonder zoek gestartin het seizoen 2014-2015 met twee cultivars. Het actieplan 'Minder virus in tulp' is een gezamenlijk initiatief van Wageningen UR, PPO Bloembollen, Boomkwekerij & Fruit, Proeftuin Zwaagdijk, KAVB,LTO en BKD
Author Co-Citation Analysis (ACA): a powerful tool for representing implicit knowledge of scholar knowledge workers
No full textIn the last decade, knowledge has emerged as one of the most important and valuable organizational assets. Gradually this importance caused to emergence of new discipline entitled ―knowledge management‖. However one of the major challenges of knowledge management is conversion implicit or tacit knowledge to explicit knowledge. Thus Making knowledge visible so that it can be better accessed, discussed, valued or generally managed is a long-standing objective in knowledge management. Accordingly in this paper author co- citation analysis (ACA) will be proposed as an efficient technique of knowledge visualization in academia (Scholar knowledge workers)
- …
