412 research outputs found

    From adrenoceptor mechanisms to clinical therapeutics: Raymond Ahlquist, PhD, 1914–1983

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    Identification of two distinct types of adrenotropic receptors, alpha and beta, by Raymond Ahlquist provided the scientific basis that enabled the development of drugs to selectively block adrenoceptor function. These pharmacotherapeutic advances have improved the care of patients with coronary and hypertensive cardiovascular disease

    Cosmic Education: The Vital Center of the Montessori Perspective

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    Starting with an analysis of the origins, the main characteristics, and the evolution of Cosmic Education, this chapter looks at the centrality cosmic education assumes in Montessori education for children aged 6 to 12. This work examines how cosmic fables, elaborated with Mario Montessori and other collaorators, allowed Maria Montessori to foster active and participatory experiences

    Engaging the digital generation

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    Comprend un index1. A Historical Perspective on Student Affairs Professionals’ Use of Digital Technology, Edmund T. Cabellon, Julie Payne-Kirchmeier : Digital technology tools have evolved drastically since 2005. Authors of this chapter highlight these changes and present a historical perspective on how student affairs administrators used digital technology tools in the past and how this history will impact future technology use.2. The Digital Identity of Student Affairs Professionals, Josie Ahlquist : Social media tools challenge the thin line between personal and professional. In this chapter, the author proposes a blended holistic digital identity for student affairs professionals that recognizes the ACPA/NASPA Student Affairs Technology competency, formation of a digital decision-making model, and utilization of personal learning networks.3. A Strategic Necessity: Building Senior Leadership’s Fluency in Digital Technology, Kara Kolomitz, Edmund T. Cabellon : Senior student affairs leaders who intentionally develop a digital mindset are committed to the academy’s ongoing evolution and support of its faculty, staff, and students. In this chapter, the authors describe how advancing SSAO’s digital fluency is the key to developing current staff through their digital example.4. College Student Development in Digital Spaces, Paul Gordon Brown : College student development theory serves as foundational knowledge in the field of student affairs. In this chapter, the author explores the impact of social and digital technologies on college students by applying theory differently and re-examining it for the digital age.5. Student Engagement Through Digital Data, Liz Gross, Jason L. Meriwether : Fundamentally, engaging students is at the core of student affairs work. In this chapter, the authors highlight various digital data sources that might uncover contemporary student engagement efforts to inform a student affairs division’s initiatives in person and online.6. Setting the Course: Strategies for Writing Digital and Social Guidelines, Laura A. Pasquini : Ultimately, student affairs educators need guiding documents to help inform their digital engagement practice. In this chapter, the author outlines specific recommendations and strategies for administrators who will steward digital technology and communication guidelines

    Insights into Tripodal Tris(pyrazolyl) Compounds as Ionophores for Potentiometric Ammonium Ion Sensing

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    The decentralisation of accurate determination of the ammonium ion (NH4+) is relevant for environmental monitoring (i. e., nitrogen cycle) and certain clinical applications (e. g., kidney and liver diseases). Potentiometric ionophore-based sensors are one alternative for these purposes in terms of versatile implementation, though the potassium ion (K+) is known to be a major source of interference. We herein investigate the use of three different tripodal tris(pyrazolyl) compounds derived from 1,3,5-triethylbenzene as NH4+ ionophores. A complete set of potentiometric experiments together with theoretical simulations reveals suitable analytical performance while demonstrating a suppression of the K+ interference given the formation of an adequate cavity in the ionophore to host NH4+ over K+ in the membrane environment. The results support the use of these electrodes in the analytical detection of NH4+ in a wide range of samples with variable contents

    A Research Agenda for New Institutional Economics

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    Contributors: J.S. Ahlquist, J.E. Aldy, D.W. Allen, J. Bednar, J.C. Cardenas, P. Castaneda Dower, R. Fernandez, S. Gehlbach, R. Gil, M.A. Golden, C. Guerriero, S. Iyer, P. Keefer, K. Kosec, R. Kunneke, C. Long, R. Macchiavello, K.J. Mayer, C. Menard, T. Mogues, M.W. Moszoro, B. Mueller, S. Oh, D. Parker, J. Prufer, P. Prufer, M. Servatka, M.M. Shirley, E. Simison, F. Sobbrio, J. Teorell, T. Terpstra, M. Vatiero, S. Voigt, S. Wallsten, G. Zanarone, D. ZiblattInternational audienceConsisting of 30 concise chapters written by top scholars, this Research Agenda probes the knowledge frontiers of issues long at the forefront of New Institutional Economics (NIE), including government, contracts and property rights. It examines pressing research questions surrounding norms, culture, and beliefs. It is designed to inform and inspire students and those starting their careers in economics, law and political science. Well-established scholars will also find the book invaluable in updating their understanding of crucial research questions and seeking new areas to explore

    Supplementary Figure 6 from The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB

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    Supplementary Figure 6. Stem cell related genes correlated with MAP17. Red color indicated positive correlations; blue color, negative correlations. Lung: P: Peitsch; Bi: Bild; E: EXPO; M: Muley; Ta: TCGA515; Tb: TCGA81; Cervix: Tc: TCGA305; A: Ahlquist; Breast: Bo: Bos; Eb: EXPO; I: Iglehart; Mi: Miller; S: Servant; So: Sotiriou; W: Wang; Td: TCGA1097; Te: TCGA528; H: Halfwerk; Colon: Ec: EXPO; O: Olschwang; Si: Sieber; Sm: Smith; D: Domany; C: Clary; Tf: TCGA286; Bu: Budinska; J: Jorissen; Ma: Marissa.</p

    Supplementary Figure 5 from The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB

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    Supplementary Figure 5. Notch pathway related genes correlated with MAP17. Red color indicated positive correlations; blue color, negative correlations. Lung: P: Peitsch; Bi: Bild; E: EXPO; M: Muley; Ta: TCGA515; Tb: TCGA81; Cervix: Tc: TCGA305; A: Ahlquist; Breast: Bo: Bos; Eb: EXPO; I: Iglehart; Mi: Miller; S: Servant; So: Sotiriou; W: Wang; Td: TCGA1097; Te: TCGA528; H: Halfwerk; Colon: Ec: EXPO; O: Olschwang; Si: Sieber; Sm: Smith; D: Domany; C: Clary; Tf: TCGA286; Bu: Budinska; J: Jorissen; Ma: Marissa.</p

    Navigating Institutional Change: The Accord, Rogernomics, and the Politics of Adjustment in Australia and New Zealand

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    This article uses a transactions approach to examine the ability of governments to develop and sustain negotiated solutions to major economic challenges. Where actors are embedded in long-term, repeated interaction, have long time horizons, and invest in monitoring and enforcement technologies, effective political exchange is more likely. In good transactions environments, policy bargains will be more easily renegotiated and therefore more flexible and durable. To examine the expectations the author looks to the puzzle posed by events in Australia and New Zealand, 1983-1996. Facing similar macroeconomic crises and with historically similar wage bargaining institutions and levels of union density both elect Labor governments, which then make opposite choices: A negotiated solution emerged in Australia but not in New Zealand. Relying on the secondary literature and interviews with key actors, the author finds support for the transactions approach. Findings here point to ways in which to broaden the study of so-called social pacts. </jats:p
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