1,214 research outputs found

    La forza lavoro straniera in Italia

    No full text
    Quali sono i costi personali e sociali di una prolungata condizione di instabilità lavorativa' Per giovani, lavoratori senior, donne, nuovi migranti il rischio è la povertà e l'esclusione sociale. La mancata integrazione nel lavoro presenta costi elevati anche per la società che si impoverisce in termini di efficienza e coesione. Il volume, basato su ricerche realizzate dalla Fondazione G. Brodolini, offre un'analisi delle nuove e vecchie forme di esclusione sociale in Italia. Ciò che accomuna i lavori qui presentati è l'attenzione al problema della precarietà sociale, quindi al ruolo della formazione e del lavoro retribuito come strumenti di inclusione. Il concetto di precarietà adottato fa riferimento non solo ai fattori che si traducono in un elevato rischio di esclusione sociale nel breve periodo, ma più in generale ai fattori che nel lungo periodo possono tradursi in una erosione delle capacità e delle risorse delle persone, aumentando il loro rischio di marginalizzazione e di povertà economica

    Giulia Veronica Varisco

    No full text
    The headword explains the biography and the contribution of the author Giulia Varisco to the children's literatur

    Pathogenicity and virulence of Acinetobacter baumannii : Factors contributing to the fitness in healthcare settings and the infected host

    No full text
    : Acinetobacter baumannii is a common cause of healthcare-associated infections and hospital outbreaks, particularly in intensive care units. Much of the success of A. baumannii relies on its genomic plasticity, which allows rapid adaptation to adversity and stress. The capacity to acquire novel antibiotic resistance determinants and the tolerance to stresses encountered in the hospital environment promote A. baumannii spread among patients and long-term contamination of the healthcare setting. This review explores virulence factors and physiological traits contributing to A. baumannii infection and adaptation to the hospital environment. Several cell-associated and secreted virulence factors involved in A. baumannii biofilm formation, cell adhesion, invasion, and persistence in the host, as well as resistance to xeric stress imposed by the healthcare settings, are illustrated to give reasons for the success of A. baumannii as a hospital pathogen

    How Do We Gender Robots? Inquiring the Relationship Between Perceptual Cues and Context of Use.

    No full text
    This paper presents a forthcoming study on the relationship between perceptual cues and context of use in the attribution of gender to a robot. We hypothesize that the context of use might drive the attribution of gender when robots have minimal gender cues. To test this hypothesis, we plan to run a 2x2 between subjects study with minimal gender cues (slightly feminine vs. slightly masculine voice) and typically gendered contexts (typically feminine vs. typically masculine) as independent variables. If our hypothesis is correct, our study will suggest that designing perceptually gender-neutral robots is not enough to make social robotics inclusive, because the context of use might still influence their genderedness

    Functional Results and Learning Curve of Endoscopic Stapes Surgery: A 10‐Year Experience

    No full text
    Objectives/Hypothesis: To assess hearing outcomes and complications of endoscopic stapes surgery by a single surgeon in a 10-year period, to compare these data with conventional microscopic procedures by the same operator, and to describe the learning curve of endoscopic stapedotomy. Study Design: Retrospective study. Methods: This is a retrospective study on patients who underwent endoscopic stapes surgery performed by the same senior surgeon, experienced both in microscopic and endoscopic techniques, between January 2009 and December 2018. Audiological data were compared, and intraoperative and postoperative complications were collected. The surgeon's last 30 cases of microscopic stapedotomy were enrolled as the control group. The results of the first 100 endoscopic stapes surgeries were analyzed separately to create a cumulative sum (CUSUM) control chart for learning curve assessment. Results: One hundred seventy-eight endoscopic and 30 microscopic stapes surgeries were included. In the endoscopic group, the mean postoperative air–bone gap was 8.2 dB. No significant differences between the endoscopic and microscopic preoperative and postoperative values were reported. A total of eight complications (4.5%) were observed in the endoscopic cohort, although in the control group, no complication occurred. The mean surgical time was 51.9 minutes in the endoscopic group versus 48.2 minutes in the microscopic group (P >.05). No association between stapedotomy success and the increasing number of procedures was found. Conclusions: Our article demonstrates that functional results from endoscopic stapes surgery are similar to those from microscopic stapes surgery in terms of both safety and efficacy. After gaining endoscopic experience, the surgical duration of stapes surgery will be adequate starting from the first cases. Level of Evidence: 4 Laryngoscope, 131:885–891, 2021

    P-type Ca channel activation by membrane depolarisation induces maturation in pig oocytes

    No full text
    The presence on pig oolemma of voltage gated Ca channels (VGCC), whose activity can be influenced by depolarisation, has been investigated exposing the oocytes to a chemical depolarisation reproducing the physiological one. To this aim and to characterise the type of VGCC present, we analysed intracellular Ca variations during perfusion of oocytes with physiological or depolarising solutions containing different selective inhibitors of VGCC. We also evaluated the effect of their activation or inhibition on oocyte maturation and the pathway involved in transduction of the depolarising stimulus to the oocyte. The results demonstrate that P type VGCC are present on pig oolemma and that their activation by depolarisation produces a prompt a sustained Ca raise able to induce the resumption of oocyte meiotic maturation through the transduction pathway involving the Ca-calmodulin dependent kinase (CaMKII).[...

    Genome diversity of domesticated Acinetobacter baumannii ATCC 19606T strains

    No full text
    : Acinetobacter baumannii has emerged as an important opportunistic pathogen worldwide, being responsible for large outbreaks for nosocomial infections, primarily in intensive care units. A. baumannii ATCC 19606T is the species type strain, and a reference organism in many laboratories due to its low virulence, amenability to genetic manipulation and extensive antibiotic susceptibility. We wondered if frequent propagation of A. baumannii ATCC 19606T in different laboratories may have driven micro- and macro-evolutionary events that could determine inter-laboratory differences of genome-based data. By combining Illumina MiSeq, MinION and Sanger technologies, we generated a high-quality whole-genome sequence of A. baumannii ATCC 19606T, then performed a comparative genome analysis between A. baumannii ATCC 19606T strains from several research laboratories and a reference collection. Differences between publicly available ATCC 19606T genome sequences were observed, including SNPs, macro- and micro-deletions, and the uneven presence of a 52 kb prophage belonging to genus Vieuvirus. Two plasmids, pMAC and p1ATCC19606, were invariably detected in all tested strains. The presence of a putative replicase, a replication origin containing four 22-mer direct repeats, and a toxin-antitoxin system implicated in plasmid stability were predicted by in silico analysis of p1ATCC19606, and experimentally confirmed. This work refines the sequence, structure and functional annotation of the A. baumannii ATCC 19606T genome, and highlights some remarkable differences between domesticated strains, likely resulting from genetic drift
    corecore