1,720,960 research outputs found
FOLLOW-UP CRONICO DI TRAPIANTO DI RENE - PROGETTO COORTE SALERNO
Introduzione : Non sono disponibili dati italiani su morbilità complessiva in trapiantati di rene (Tx-rene). Il Progetto Coorte Salerno è un'analisi osservazionale su mortalità, co-morbilità e predittori rischio in Tx-rene.
Metodologia : Dopo 1 anno da ultimo Tx-rene, i pazienti sono arruolati e mantenuti nello studio se effettuano almeno 3 visite controllo/anno. Data inizio follow -up è anno di arruolamento. Data fine follow -up è ultimo anno con controlli regolari, oppure anno di rientro in dialisi cronica, oppure anno di decesso. La raccolta dati ha compreso una fase retrospettiva per dati già disponibili ed una prospettica, realizzate con modalità identiche da medici addestrati che codificano in modo standardizzato le informazioni della cartella clinica.
Risultati : L'analisi include 679 pazienti con follow -up >1 anno (64% maschi). Età al Tx-rene era 43±14 anni, durata follow-up 9.5±6.4 anni (prodotto anni-paziente=6442). Espressa come numero eventi/100 pazienti/10 anni (intervallo confidenza 95%), l'incidenza era 15.5 per rientro in dialisi (12.7/18.3) e 9.6 per mortalità (7.3/12.0). Frequenza di eventi non-letali era: 35.9% per infezioni virali (CMV, EBV, Herpes); 22.1% per infezioni batteriche (broncopolmonite/pielonefrite/sepsi), 18.0% per malattie cardiovascolari maggiori de-novo (infarto miocardio, ictus, scompenso cardiaco), 14.9% per diabete de-novo, 13.7% per neoplasie, 9.3% per re-intervento su anastomosi, 6.4% per rigetto, 2.5% per necrosi asettica testa femore. Dati retrospettivi e dati prospettici non differivano significativamente.
Conclusioni : In Tx-rene, il decesso è un evento poco più raro del rientro in dialisi e, pertanto, andrebbe incluso tra obiettivi di studi clinici. Infezioni virali/batteriche e malattie cardiovascolari sono le co-morbilità più comuni
[Atypical mycobacterial infection after kidney transplant: two clinical cases]
Infections are an important cause of morbidity and mortality during kidney transplant. In areas where tuberculosis is not endemic, Mycobacteria other than tuberculosis (MOOT), also known as 'atypical' Mycobacteria, are more frequently involved in mycobacterial infections than M. tuberculosis. The incidence of MOOT infection in renal transplant recipients ranges from 0.16 to 0.38 percent. This low rate of reported incidence is, however, often due to delay in diagnosis and lack of therapeutic protocols. Further difficulty is caused by the interaction of antimycobacterial drugs with the post-transplant immunosuppressive regimen, necessitating close monitoring of plasma concentrations and careful dose modification. We present two cases of Mycobacterium Chelonae infection in kidney transplant recipients which differ in both clinical presentation and pharmacological approach
FOLLOW-UP CRONICO DI TRAPIANTO DI RENE - PROGETTO COORTE SALERNO
Introduzione : Non sono disponibili dati italiani su morbilità complessiva in trapiantati di rene (Tx-rene). Il Progetto Coorte Salerno è un'analisi osservazionale su mortalità, co-morbilità e predittori rischio in Tx-rene.
Metodologia : Dopo 1 anno da ultimo Tx-rene, i pazienti sono arruolati e mantenuti nello studio se effettuano almeno 3 visite controllo/anno. Data inizio follow -up è anno di arruolamento. Data fine follow -up è ultimo anno con controlli regolari, oppure anno di rientro in dialisi cronica, oppure anno di decesso. La raccolta dati ha compreso una fase retrospettiva per dati già disponibili ed una prospettica, realizzate con modalità identiche da medici addestrati che codificano in modo standardizzato le informazioni della cartella clinica.
Risultati : L'analisi include 679 pazienti con follow -up >1 anno (64% maschi). Età al Tx-rene era 43±14 anni, durata follow-up 9.5±6.4 anni (prodotto anni-paziente=6442). Espressa come numero eventi/100 pazienti/10 anni (intervallo confidenza 95%), l'incidenza era 15.5 per rientro in dialisi (12.7/18.3) e 9.6 per mortalità (7.3/12.0). Frequenza di eventi non-letali era: 35.9% per infezioni virali (CMV, EBV, Herpes); 22.1% per infezioni batteriche (broncopolmonite/pielonefrite/sepsi), 18.0% per malattie cardiovascolari maggiori de-novo (infarto miocardio, ictus, scompenso cardiaco), 14.9% per diabete de-novo, 13.7% per neoplasie, 9.3% per re-intervento su anastomosi, 6.4% per rigetto, 2.5% per necrosi asettica testa femore. Dati retrospettivi e dati prospettici non differivano significativamente.
Conclusioni : In Tx-rene, il decesso è un evento poco più raro del rientro in dialisi e, pertanto, andrebbe incluso tra obiettivi di studi clinici. Infezioni virali/batteriche e malattie cardiovascolari sono le co-morbilità più comuni
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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