196,852 research outputs found
Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro
No full textC.-F. Lim, N. M. Loidl, J. A. Kennedy, D. J. Topliss, J. R. Stockig
Rhinolophus luctoides Volleth, Loidl, Mayer, Yong, Muller and Heller 2015
No full textRhinolophus luctoides Volleth, Loidl, Mayer, Yong, Müller and Heller, 2015 Rhinolophus luctoides Volleth, Loidl, Mayer, Yong, Müller and Heller, 2015: 4; Ulu Gombak, Selangor, MALAYSIA, 600 m (K. -G. Heller and M. Volleth, collector; SMF 87483) [3]. Barcode Index Number: There are no DNA barcodes recorded under this name on BOLD. Remarks: R. luctoides and R. morio were previously synonymised under R. luctus but are distinct from R. luctus on the basis of molecular and morphological characters. R. luctoides has a larger ratio of lower toothrow length to mandible length and larger baculum length compared to R. morio [3]. IUCN status: Not Evaluated but Least Concern as R. luctus. Recorded at: Selangor: 5 km north-east of the Ulu Gombak [3]; Pahang: Cameron Highland and Genting Highland [3]. Individuals were captured in selectively logged dipterocarp forest at elevations higher than 600 m and in montane forest [3]. See R. morio for records of R. luctus.Published as part of Voon-Ching Lim, Rosli Ramli, Subha Bhassu & John-James Wilson, 2017, A checklist of the bats of Peninsular Malaysia and progress towards a DNA barcode reference library, pp. 1-65 in PLoS ONE 12 (7) on pages 32-33, DOI: 10.1371/journal.pone.0179555, http://zenodo.org/record/425135
Effect of loop diuretics and nonsteroidal antiinflammatory drugs on thyrotropin release by rat anterior pituitary cells in vitro
No full textChen-Fee Lim, Nicole M. Loidl, Jennifer A. Kennedy, Duncan J. Topliss, Jan R. Stockig
Prigogine-Defay ratio of glassy freezing scales with liquid fragility
No full textA detailed study of published experimental data for a variety of materials on the incremental variation of heat capacity, thermal expansion, and compressibility at glassy freezing reveals a striking dependence of the Prigogine-Defay ratio R on the fragility index m. At high m, R approaches values of ∼1, the Ehrenfest expectation for second-order continuous phase transitions, while R reaches values >20 for low fragilities. We explain this correlation by the degree of separation of the glassy freezing temperature from a hidden phase transition into an ideal low-temperature glass
Crystal melting influenced by particle cooperativity of the liquid
No full textRecently, a universal relation between the thermal expansion coefficient of glasses αg, their glass-transition temperature Tg, and the so-called fragility index m of the corresponding supercooled liquid state was found to be valid for more than 200 glass formers, namely αg/m ∝ 1/Tg [Lunkenheimer et al., Nat. Phys. 19, 694 (2023)]. Here we show that this could also have far-reaching consequences for our understanding of crystal melting. Namely, when considering the empirically founded 2/3 rule, stating that the ratio of Tg and the melting temperature Tm is about 2/3 for almost all materials, for crystals a similar relation, αc/m ∝ 1/Tm, should apply. Indeed, we find that the available experimental data are quite consistent with such a relation. This implies that the melting of a crystal into an ordinary (nonsupercooled) liquid is influenced by the fragility, a property quantifying the non-Arrhenius dynamics in the supercooled-liquid state of the material. We argue that this can be explained by a significant enhancement of the “ideal” (noncooperative) melting temperature arising from the cooperativity of the particle motion in the liquid state above Tm. Therefore, a reassessment of the currently widely accepted microscopic understanding of crystal melting, still founded on the general ideas that lead to the time-honored Lindemann melting criterion, may be necessary
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors
No full textNovel 3-(4-aroyl-2-pyrrolyl)-N-hydroxy-2-propenamides are disclosed as a new class of histone deacetylase (HDAC) inhibitors. Three-dimensional structure-based drug design and conformational analyses into the histone deacetylase-like protein (HDLP) catalytic core suggested the synthesis and biological evaluation of compounds 7a−h. Experimental pKi values are in good agreement with VALIDATE predicted pKi values of new derivatives. All compounds 7a−h show HDAC inhibitory activity in the micromolar range, with 7e as the most potent derivative (IC50 = 1.9 μM). The influence of the 4‘-substituent in the aroyl moiety is not significant for the inhibitory activity, as all compounds 7a−g show IC50 values between 1.9 and 3.9 μM. Otherwise, the unsaturated chain linking the pyrrole ring to the hydroxamic acid group is clearly important for the anti-HDAC activity, the saturated analogue 7h being 10-fold less active than the unsaturated counterpart 7a
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