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Korelasi Right Ventricular Outflow Tract Systolic Excursion dengan Forced Expiratoy Volume-1 Pada Pasien Penyakit Paru Obstruktif Kronik
No full textPenyakit paru obstruktif kronik (PPOK) merupakan salah satu penyebab morbiditas dan mortalitas terbanyak di dunia dengan prevalensi yang terus meningkat. Manifestasi ekstrapulmonal dari PPOK salah satunya pada sistem kardiovaskular yang terjadi pada 50% penderita PPOK yang dirawat, diantaranya gagal jantung kanan, hipertensi pulmonal, dan penyakit jantung iskemik. Gagal jantung kanan merupakan nilai prognostik yang buruk bagi pasien PPOK dan dianggap sebagai stadium akhir dari penyakit paru. Pemeriksaan spirometri merupakan baku emas untuk menilai fungsi paru, dengan parameter forced expiratory volume-1 (FEV1) untuk menilai derajat obstruksi saluran pernafasan. Pemeriksaan right ventricular outflow tract systolic excursion (RVOT-SE) dengan ekokardiografi merupakan parameter baru untuk menilai fungsi sistolik ventrikel kanan dengan sensitifitas dan spesifisitas 100%. Penelitian ini bertujuan untuk menilai korelasi antara RVOT-SE dengan FEV1 pada penderita PPOK. Dilakukan penelitian observasional dengan rancangan potong lintang, periode Oktober 2013-Januari 2014 di Instalasi Rawat Jalan Paru Rumah Sakit Dr. Hasan Sadikin Bandung. Rumus korelasi digunakan untuk menentukan besar sampel, didapat jumlah sampel minimal sebesar 32 subjek. Pemilihan subjek dengan consecutive sampling sesuai kriteria inklusi dan eksklusi. Subjel dilakukan pemeriksaan spirometri dan ekokardiografi. Uji korelasi Pearson dan korelasi parsial dilakukan dengan menggunakan perangkat lunak statistical product and service solution versi 17. Hasil dari 32 subjek, sebagian besar laki-laki dengan rata-rata usia 66,53±10,08 tahun, rata-rata FEV1 51,42±12,11%, rata-rata RVOT-SE 0,82±0,28 cm, median waktu sejak terdiagnosis PPOK 7,05(27+5) tahun, dan sebagian besar memiliki frekuensi eksaserbasi <2 kali per tahun (78%). Uji korelasi Pearson menunjukkan tidak ada korelasi antara RVOT-SE dengan FEV1 (r=0,228; p=0,209). Uji korelasi parsial dengan menyesuaikan variabel waktu sejak terdiagnosis PPOK menunjukkan korelasi positif bermakna antara RVOT-SE dengan FEV1 (r=0,315; p=0,042). Simpulan, terdapat korelasi positif bermakna antara RVOT-SE dengan FEV1 pada penderita PPOK setelah menyesuaikan variabel waktu sejak terdiagnosis PPOK.Kata kunci: forced expiratory volume-1, penyakit paru obstruktif kronik, right ventricular outflow tract systolic excursion. Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality with increasingly prevelance throughout the world. COPD is associated with significant extrapulmonary effects among which cardiac manifestation is the most common, accounts of 50% of all hospitalization,consists of right heart failure, pulmonary hypertension and ischaemic heart disease. Right heart failure is an important prognostic factor and considered to be an end stage pulmonary disease. Spirometry is the gold standard for accurate and repeatable measurement of lung function, whereas forced expiratory volume-1 (FEV1) represent the severity of airway obstruction. Echocardiography provides a rapid, noninvasive and accurate method to evaluate right heart function. A novel parameter right ventricular outflow tract systolic excursion (RVOT-SE) can identify reduced right ventricular function with 100% sensitivity and 100% specificity.This study aims to analyze the correlation of RVOT-SE and FEV1 in COPD patients. An observational cross-sectional study was done during October 2013- January 2014 at Pulmonology outpatient installation of Dr. Hasan Sadikin Hospital,Bandung. Sample was chosen by consecutive sampling according to the inclusion and exclusion criteria. The selected samples were evaluated by spiromtery and echocardiography. Pearson correlation and partial correlation was analyzed using statistical product and service solution version 17 software.Results of total of 32 samples mostly male with mean age 66,53±10,08 years, mean FEV1 51,42±12,11%, mean RVOT-SE 0,82±0,28 cm, median of time since COPD diagnosis 7,05(275) years, and mostly <2 exacerbation a year (78%).There was no correlation between RVOT-SE and FEV1 (r=0,228; p=0,209) on bivariat analysis. Partial correlation with adjustment of time since COPD diagnosis showed a signifcant positive correlation between RVOT-SE and FEV1 (r=0,315; p=0,042). We conclude that there is a significant positive correlation between RVOT-SE and FEV1 after adjusting the time since COPD diagnosis.Keywords: forced expiratory volume-1, chronic obstructive pulmonary disease, right ventricular outflow tract systolic excursion
Korelasi Right Ventricular Outflow Tract Systolic Excursion dengan Forced Expiratoy Volume-1 Pada Pasien Penyakit Paru Obstruktif Kronik
No full textPenyakit paru obstruktif kronik (PPOK) merupakan salah satu penyebab morbiditas dan mortalitas terbanyak di dunia dengan prevalensi yang terus meningkat. Manifestasi ekstrapulmonal dari PPOK salah satunya pada sistem kardiovaskular yang terjadi pada 50% penderita PPOK yang dirawat, diantaranya gagal jantung kanan, hipertensi pulmonal, dan penyakit jantung iskemik. Gagal jantung kanan merupakan nilai prognostik yang buruk bagi pasien PPOK dan dianggap sebagai stadium akhir dari penyakit paru. Pemeriksaan spirometri merupakan baku emas untuk menilai fungsi paru, dengan parameter forced expiratory volume-1 (FEV1) untuk menilai derajat obstruksi saluran pernafasan. Pemeriksaan right ventricular outflow tract systolic excursion (RVOT-SE) dengan ekokardiografi merupakan parameter baru untuk menilai fungsi sistolik ventrikel kanan dengan sensitifitas dan spesifisitas 100%. Penelitian ini bertujuan untuk menilai korelasi antara RVOT-SE dengan FEV1 pada penderita PPOK. Dilakukan penelitian observasional dengan rancangan potong lintang, periode Oktober 2013-Januari 2014 di Instalasi Rawat Jalan Paru Rumah Sakit Dr. Hasan Sadikin Bandung. Rumus korelasi digunakan untuk menentukan besar sampel, didapat jumlah sampel minimal sebesar 32 subjek. Pemilihan subjek dengan consecutive sampling sesuai kriteria inklusi dan eksklusi. Subjel dilakukan pemeriksaan spirometri dan ekokardiografi. Uji korelasi Pearson dan korelasi parsial dilakukan dengan menggunakan perangkat lunak statistical product and service solution versi 17. Hasil dari 32 subjek, sebagian besar laki-laki dengan rata-rata usia 66,53±10,08 tahun, rata-rata FEV1 51,42±12,11%, rata-rata RVOT-SE 0,82±0,28 cm, median waktu sejak terdiagnosis PPOK 7,05(27+5) tahun, dan sebagian besar memiliki frekuensi eksaserbasi <2 kali per tahun (78%). Uji korelasi Pearson menunjukkan tidak ada korelasi antara RVOT-SE dengan FEV1 (r=0,228; p=0,209). Uji korelasi parsial dengan menyesuaikan variabel waktu sejak terdiagnosis PPOK menunjukkan korelasi positif bermakna antara RVOT-SE dengan FEV1 (r=0,315; p=0,042). Simpulan, terdapat korelasi positif bermakna antara RVOT-SE dengan FEV1 pada penderita PPOK setelah menyesuaikan variabel waktu sejak terdiagnosis PPOK.Kata kunci: forced expiratory volume-1, penyakit paru obstruktif kronik, right ventricular outflow tract systolic excursion. Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality with increasingly prevelance throughout the world. COPD is associated with significant extrapulmonary effects among which cardiac manifestation is the most common, accounts of 50% of all hospitalization,consists of right heart failure, pulmonary hypertension and ischaemic heart disease. Right heart failure is an important prognostic factor and considered to be an end stage pulmonary disease. Spirometry is the gold standard for accurate and repeatable measurement of lung function, whereas forced expiratory volume-1 (FEV1) represent the severity of airway obstruction. Echocardiography provides a rapid, noninvasive and accurate method to evaluate right heart function. A novel parameter right ventricular outflow tract systolic excursion (RVOT-SE) can identify reduced right ventricular function with 100% sensitivity and 100% specificity.This study aims to analyze the correlation of RVOT-SE and FEV1 in COPD patients. An observational cross-sectional study was done during October 2013- January 2014 at Pulmonology outpatient installation of Dr. Hasan Sadikin Hospital,Bandung. Sample was chosen by consecutive sampling according to the inclusion and exclusion criteria. The selected samples were evaluated by spiromtery and echocardiography. Pearson correlation and partial correlation was analyzed using statistical product and service solution version 17 software.Results of total of 32 samples mostly male with mean age 66,53±10,08 years, mean FEV1 51,42±12,11%, mean RVOT-SE 0,82±0,28 cm, median of time since COPD diagnosis 7,05(27ï€5) years, and mostly <2 exacerbation a year (78%).There was no correlation between RVOT-SE and FEV1 (r=0,228; p=0,209) on bivariat analysis. Partial correlation with adjustment of time since COPD diagnosis showed a signifcant positive correlation between RVOT-SE and FEV1 (r=0,315; p=0,042). We conclude that there is a significant positive correlation between RVOT-SE and FEV1 after adjusting the time since COPD diagnosis.Keywords: forced expiratory volume-1, chronic obstructive pulmonary disease, right ventricular outflow tract systolic excursion
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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