1,497 research outputs found

    First person – Vincenzo Torraca

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    First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Vincenzo Torraca is first author on ‘ Transcriptional profiling of zebrafish identifies host factors controlling susceptibility toShigella flexneri’, published in DMM. Vincenzo conducted the research described in this article while he was a Marie Skłodowska-Curie Postdoctoral Fellow at Imperial College London, UK and an ISSF (Institutional Strategic Support Fund)-Wellcome Fellow at the London School of Hygiene and Tropical Medicine, UK, where most of the work was carried out in Prof. Serge Mostowy's lab. He has just started his own group at King's College London, investigating host-pathogen interactions and antimicrobial resistance for globally relevant bacterial pathogens, such as Shigella and E. coli, using zebrafish as an in vivo model

    Africa II

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    This map appears in another example of the several translations of Ptolemy's Geography. This one, in Latin, was a translation directly from the Greek done by Pirckheimer and revised by Giuseppe Moleti. Stevens (pg. 51) notes that the maps in this version are identical to the maps in the Italian 1561 edition, also published by Vincenzo Valgrisi

    Africa I

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    This map appears in another example of the several translations of Ptolemy's Geography. This one, in Latin, was a translation directly from the Greek done by Pirckheimer and revised by Giuseppe Moleti. Stevens (pg. 51) notes that the maps in this version are identical to the maps in the Italian 1561 edition, also published by Vincenzo Valgrisi. Includes the verso and the original sellers information

    Solid oxide fuel cell performance comparison fuelled by methane, MeOH, EtOH and diesel surrogate C8H18

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    Carbon deposition is a major cause of degradation in solid oxide fuel cell systems. The ability to predict carbon formation in reforming processes is thus absolutely necessary for stable operation of solid oxide fuel cell systems.In the open literature it is found that thesteam input is always considered in large excess compared to what required by the reforming process with the purpose of reducing carbon formation and avoiding rapid degradation of the cell performance. This makes it difficult to consistently compare system performance with different fuels. In this work, the molar compositions at equilibrium is calculated for a minimum steam to carbon ratio for each fuel type.We carry out a thermodynamic analysis of fuel/steam system, using Gibbs Free Energy minimization method. A mathematical relationship between Lagrange's multipliers and carbon activity in the gas phase was deduced. Minimum steam required for the reforming process for each fuel was related to the heat required for the reforming process and fuel cell open circuit voltage.Furthermore, in an experimental test, steam reforming product compositions were used to evaluate and compare SOFC performance with different hydrocarbons.Comparing the model to the experimental activity, it is revealed that at temperatures exceeding 800°C the gas composition is dominated by hydrogen and carbon monoxide for any of the fuels considered leading to similar cell polarization curves performance for different fuels.The main effect on the performance is related to OCV values which are dependent on different steam content for each fuel. It was concluded that the magnitude of the heat requested for the fuel reforming process is the major difference in system performance when comparing different fuels. However, reforming kinetic effects can become predominant rather than thermodynamics, especially at lower temperatures

    Evaluation of the Potential of Biofilm Formation of Bifidobacterium longum subsp. infantis and Lactobacillus reuteri as Competitive Biocontrol Agents Against Pathogenic and Food Spoilage Bacteria

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    This study proposes to exploit the in vivo metabolism of two probiotics (Bifidobacterium longum subsp. infantis and Lactobacillus reuteri) which, upon adhesion on a solid surface, form a biofilm able to control the growth of pathogenic and food spoilage bacteria. The results showed that pathogenic cell loads were always lower in presence of biofilm (6.5–7 log CFU/cm2) compared to those observed in its absence. For Escherichia coli O157:H7, a significant decrease (>1–2 logarithmic cycles) was recorded; for Listeria monocytogenes, Staphylococcus aureus, and Salmonella enterica, cell load reductions ranged from 0.5 to 1.5 logarithmic cycles. When tested as active packaging, the biofilm was successfully formed on polypropylene, polyvinyl chloride, greaseproof paper, polyethylene and ceramic; the sessile cellular load ranged from 5.77 log CFU/cm2 (grease-proof paper) to 6.94 log CFU/cm2 (polyethylene, PE). To test the potential for controlling the growth of spoilage microorganisms in food, soft cheeses were produced, inoculated with L. monocytogenes and Pseudomonas fluorescens, wrapped in PE pellicles with pre-formed biofim, packed both in air and under vacuum, and stored at 4 and 15 °C: an effective effect of biofilms in slowing the decay of the microbiological quality was recorded

    Vincenzo Errante

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    The headword explains the biography and the contribution of the author Vincenzo Errante to the children's literatur

    Pericentric chromosome 8 inversion associated with the 5'RUNX1/3'CBFA2T1 gene in acute myeloid leukemia cases

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    In the present paper we report pericentric chromosome 8 inversions in two (2.4%) of 82 acute myeloid leukemia (AML) cases characterized by the 5'RUNX1/3'CBFA2T1 fusion gene. Molecular cytogenetic characterization was achieved using appropriate bacterial artificial chromosome (BAC) and P1 artificial chromosome (PAC) probes in fluorescence in situ hybridization (FISH) experiments. In these two cases the fusion gene was detected on the der(8) short arm, resulting from a pericentric chromosome 8 inversion followed by a t(8;21) rearrangement. These results suggest that heterogeneous mechanisms can lead to the generation of the 5'RUNX1/3'CBFA2T1chimeric gene
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