313 research outputs found

    Detecting rotational disorder in heme proteins: A comparison between resonance Raman spectroscopy, nuclear magnetic resonance, and circular dichroism

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    In heme proteins, the canonical and reversed conformations result from the rotation of the heme group by 180° about the α,γ‐meso axis in the protein pocket. The coexistence of the two different heme orientations has been observed both in proteins reconstituted with hemin and in some native proteins. The reversal of the heme orientation can also change certain functional properties of heme proteins. Complementing the results from other experimental techniques, like circular dichroism and nuclear magnetic resonance, resonance Raman spectroscopy provides detailed information on the structure of the reversed heme. This allows one to elucidate the effects of the heme rotation on the vibrational spectra of the peripheral substituents, especially the vinyl groups. Furthermore, the combination of resonance Raman spectroscopy on single crystals and solution samples of heme proteins is proposed to be a sensitive tool to detect heme orientational disorder, even in the absence of structural data

    Poor vigilance affects attentional orienting triggered by central uninformative gaze and arrow cues

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    Behaviour and neuroimaging studies have shown that poor vigilance (PV) due to sleep deprivation (SD) negatively affects exogenously cued selective attention. In the current study, we assessed the impact of PV due to both partial SD and night-time hours on reflexive attentional orienting triggered by central un-informative eye-gaze and arrow cues. Subjective mood and interference performance in emotional Stroop task were also investigated. Twenty healthy participants performed spatial cueing tasks using central directional arrow and eye-gaze as a cue to orient attention. The target was a word written in different coloured inks. The participant's task was to identify the colour of the ink while ignoring the semantic content of the word (with negative or neutral emotional valence). The experiment took place on 2 days. On the first day, each participant performed a 10-min training session of the spatial cueing task. On the second day, half of participants performed the task once at 4:30 p.m. (BSL) and once at 6:30 a.m. (PV), whereas the other half performed the task in the reversed order. Results showed that mean reaction times on the spatial cueing tasks were worsened by PV, although gaze paradigm was more resistant to this effect as compared to the arrow paradigm. Moreover, PV negatively affects attentional orienting triggered by both central un-informative gaze and arrow cues. Finally, prolonged wakefulness affects self-reported mood but does not influence interference control in emotional Stroop task

    “VENERE PRIVATA” DA SCERBANENCO A BACILIERI: LINGUA, STILE E RETORICA DALLA LETTERATURA AL FUMETTO

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    Il romanzo Venere privata di Giorgio Scerbanenco (1966) è tra i capostipiti del giallo italiano contemporaneo e introduce il personaggio Duca Lamberti, medico radiato dall’ordine per aver praticato l’eutanasia su una paziente e diventato, una volta scontata la pena, consulente della polizia milanese. La narrazione, la lingua e lo stile dell’autore, già studiati da diversi interventi specialistici, sono ora oggetto dell’adattamento a fumetti di Paolo Bacilieri, apparso a puntate sulla rivista Linus a partire dall’agosto 2021. La pubblicazione dovrebbe concludersi in rivista entro l’anno, ed è prevista per l’autunno 2022 l’edizione integrale in volume per Oblomov. Il presente studio affronta le prime sei puntate dell’adattamento, ne studia la lingua e lo stile in relazione al testo originale, la raffigurazione di ambienti, personaggi e situazioni in relazione agli elementi diegetici del romanzo e a modelli esterni usati da Bacilieri, infine la configurazione degli elementi iconici e verbali nelle tavole in prospettiva retorica. Ciò consente di comprendere non solo il processo e il concetto di adattamento attuati dall’autore, ma anche la lettura e l’interpretazione che questi ha fatto del racconto, della lingua e dello stile del testo originario.   Venere privata from Scerbanenco and Bacilieri: language, style and rhetoric from literature to comics Giorgio Scerbanenco’s novel Venere privata (1966) is among the progenitors of the contemporary Italian detective story and introduces the character Duca Lamberti, a doctor disbarred for practicing euthanasia on a patient and becoming, once he has served his sentence, a consultant to the Milanese police. The author’s narrative, language and style, which have already been studied by several specialist papers, are now the subject of Paolo Bacilieri\u27s comic book adaptation, appearing serialized in Linus magazine starting in August 2021. The publication is expected to be completed in the magazine within the year, and a full volume edition for Oblomov is planned for Fall 2022. The present study deals with the first six installments of the adaptation, studying the language and style in relation to the original text, the depiction of the environments, characters and situations in relation to the diegetic elements of the novel and external models used by Bacilieri, and finally the configuration of the iconic and verbal elements in the tables in rhetorical perspective. This allows us to understand not only the process and concept of adaptation implemented by the author, but also his reading and interpretation of the story, language and style of the original text

    Alerting, Orienting and Executive Control: The effects of sleep deprivation

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    Sleep deprivation has been shown to alter attentional functions, like sustaining an alert state over a period of time (vigilance or tonic alerting). However, the effects of sleep loss on both orienting and executive control are not still clear, and no study has assessed whether sleep deprivation might affect the relation among these three attentional abilities. In this study we used the Attentional Network Test (ANT) in order to investigate the efficiency of the three networks: alerting, orienting and executive control. Eighteen right-handed male subjects participated to the experiment, which took place on two consecutive days. On the first day, in order to evaluate baseline condition, the subjects performed the ANT; on the second day, during 24 h of sleep loss, the same task was performed two times, at 5.00 p.m and at 4.00 a.m. Results showed an overall slowing of reaction time in the nocturnal session, indicating a decrease of vigilance. The orienting network influenced the executive function network in a positive way (the flanker effect was smaller for spatial cue than for the other type of cues). However, results did not confirm an effect of sleep deprivation on both executive control and orienting systems, suggesting the independence between the tonic component of the alerting and the other two attentional systems

    Datasets of the article "From Classification to Quantification in Tweet Sentiment Analysis"

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    Datasets used for the following SNAM paper: --------------------------------------------------------------------------------------------------- Title: From Classification to Quantification in Tweet Sentiment Analysis Authors: Wei Gao and Fabrizio Sebastiani Organization: Qatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar --------------------------------------------------------------------------------------------------- [Content] * SemEval2013, SemEval2014, SemEval2015 datasets: - semeval.train.feature.txt: Training set for learning sentiment models at development stage - semeval.dev.feature.txt: Held-out set for tuning parameters - semeval.train+dev.feature.txt: Training set for learning the final sentiment model - semeval13.test.feature.txt: SemEval2013 test set - semeval14.test.feature.txt: SemEval2014 test set - semeval15.test.feature.txt: SemEval2015 test set * Other datasets: semeval2016, sanders, sst, omd, hcr, gasp, wa, wb - X.train.feature.txt: Training set for learning sentiment models at development stage - X.dev.feature.txt: Held-out set for tuning parameters - X.train+dev.feature.txt: Training set for learning the final sentiment model - X.test.feature.txt (or X.dev-test.feature.txt for semeval2016 only): Test set where X is one of semeval2016, sanders, sst, omd, hcr and gasp. * Training files are saved in ./data/train directory, and held-out and test files are in ./data/test directory For more details, please refer to the paper. [Citation] You can cite the following paper when referring to the dataset: @article{gao2016classification, title={From classification to quantification in tweet sentiment analysis}, author={Gao, Wei and Sebastiani, Fabrizio}, journal={Social Network Analysis and Mining}, volume={6}, number={1}, pages={19}, year={2016}, publisher={Springer}

    : Two Datasets for the Computational Authorship Analysis of Medieval Latin Texts

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    We present and make available MedLatinEpi and MedLatinLit, two datasets of medieval Latin texts to be used in research on computational authorship analysis. MedLatinEpi and MedLatinLit consist of 294 and 30 curated texts, respectively, labelled by author; MedLatinEpi texts are of epistolary nature, while MedLatinLit texts consist of literary comments and treatises about various subjects. As such, these two datasets lend themselves to supporting research in authorship analysis tasks, such as authorship attribution, authorship verification, or same-author verification. Along with the datasets, we provide experimental results, obtained on these datasets, for the authorship verification task, i.e., the task of predicting whether a text of unknown authorship was written by a candidate author. We also make available the source code of the authorship verification system we have used, thus allowing our experiments to be reproduced, and to be used as baselines, by other researchers. We also describe the application of the above authorship verification system, using these datasets as training data, for investigating the authorship of two medieval epistles whose authorship has been disputed by scholars. on computational authorship analysis. MedLatinEpi and MedLatinLit consist of 294 and 30 curated texts, respectively, labelled by author; MedLatinEpi texts are of epistolary nature, while MedLatinLit texts consist of literary comments and treatises about various subjects. As such, these two datasets lend themselves to supporting research in authorship analysis tasks, such as authorship attribution, authorship verification, or same-author verification. Along with the datasets, we provide experimental results, obtained on these datasets, for the authorship verification task, i.e., the task of predicting whether a text of unknown authorship was written by a candidate author. We also make available the source code of the authorship verification system we have used, thus allowing our experiments to be reproduced, and to be used as baselines, by other researchers. We also describe the application of the above authorship verification system, using these datasets as training data, for investigating the authorship of two medieval epistles whose authorship has been disputed by scholars
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