101,744 research outputs found
Trois études sur la littérature prophétique. Ernst Sellin, Das Zwölf prophetenbuch übersezt und erklaert, deuxième et troisième édition, Zweite Holfte : Nahum-Maleachi (Kommentar zum Alten Testament), Leipzig, Deichert, 1930. Joh. Lindblom, Die literarische Gattung der prophetischen Literatur, eine literarg eschichtliche Untersuchung zum Α. T. Upsala, Lundequist, 1924. Joh. Lindblom, Hosea literarisch untersucht , Helsingfors, Akademiska Bokhandeln, 1927.
No full textLods Adolphe François Paul. Trois études sur la littérature prophétique. Ernst Sellin, Das Zwölf prophetenbuch übersezt und erklaert, deuxième et troisième édition, Zweite Holfte : Nahum-Maleachi (Kommentar zum Alten Testament), Leipzig, Deichert, 1930. Joh. Lindblom, Die literarische Gattung der prophetischen Literatur, eine literarg eschichtliche Untersuchung zum Α. T. Upsala, Lundequist, 1924. Joh. Lindblom, Hosea literarisch untersucht , Helsingfors, Akademiska Bokhandeln, 1927. In: Revue d'histoire et de philosophie religieuses, 11e année n°2, Mars-avril 1931. pp. 211-219
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
1928:1
No full textFRÅN DEN TEOLOGISKA SAMTIDEN
ARTIKLAR
Gustaf Aulén: Försoningsmotivet inom den kristna idéhistorien
Johannes Lindblom: Exegetisk och pneumatisk bibelutläggning
TEOLOGISK LITTERATUR
Anders Nygren: Till den nyaste religionsfilosofiska litteraturen
Arvid Runestam: Calvin-forskningens nuvarande läge (forts.)
Emil Liedgren: Den andliga sången på anglosachsisk mark. Anm. av Yngve Brilioth
V. T. Rosenqvist: Frans Ludvig Schaumann, I. Anm. av Yngve Brilioth
G. O. Rosenqvist: Kyrkans förkunnelse och nutidsläget. Anm. av Otto Centerwall
Paul Althaus: Evangelium und Leben. Das Wesen des evangelischen Gottesdienstes. Anm. av Gustaf Aulé
Viral infections in children with cancer
No full textViral infections are the most common cause of infection morbidity in children. Nevertheless, few studies have been devoted to exploring the viral panorama in children receiving chemotherapy for cancer. The present thesis aims to study viral infections in children with cancer with special focus on Parvovirus B19 (B19) and viral infections during episodes of neutropenic fever.B19 was for many years, believed to be a lytic virus cleared by the humoral response. However, subsequent studies in our laboratory led to the discovery of a B19-specific CD8+ T-cell response persisting for up to two years indicating persistence of antigen. To learn more about the kinetics of B19 viral load and with the aim of developing a more sensitive method, we applied a Taqman-based quantitative PCR with a sensitivity of 2 geq/mL. With this assay we reassessed consecutive collected samples from five acutely infected patients and found a persistent viral load of 103 - 105geq/mL, not detected with the less sensitive qualitative PCR. This challenges our current understanding about the virus pathogenesis and suggests that B19 frequently causes persistent infection.As long as twenty years ago, complications from B19 infection were found in children undergoing anti cancer treatment. To further study the pathogenesis of B19 in a group of children with proven or suspected malignant disorders, bone marrow aspirates obtained were supplemented with testing for parvovirus B19 DNA. Here we could confirm results from other studies in which severe cytopenia led to multiple transfusions, withdrawal or postponed chemotherapy and B19 infection mimicking a relapse. Moreover, for the first time, we were also able to include a control group of B19-negative patients and compare them with the B19 DNA-positive patients during maintenance therapy for acute lymphoblastic leukemia. Particularly striking was the number of treatment days lost in the B19 DNA-positive group, strongly indicating the potential of this factor to affect treatment outcome.Furthermore, we did a one year prospective study on children presenting with neutropenic fever at two pediatric oncology units in Stockholm, Sweden and Sydney, Australia, focusing on viral infections. Little is known about the etiology behind neutropenic fever and the microbial detection in 15-30% of the cases corresponds mostly to bacterial findings. In this study we showed that respiratory virus RNA/DNA are a common finding in nasopharyngeal aspirates from children presenting with neutropenic fever. Moreover, the addition of PCR-based viral diagnostic tools to the routinely performed bacterial blood culture increased the detection rate of a possible etiological agent to two thirds of the cases.In conclusion, this thesis provides support for viral infections as a common cause of morbidity also in children receiving treatment for cancer. Neglect of viral diagnostic efforts may lead to inappropriate clinical management or suboptimal therapy intensity.List of scientific papersI. Lindblom A, Isa A, Norbeck O, Wolf S, Johansson B, Broliden K, Tolfvenstam T (2005). Slow clearance of human parvovirus B19 viremia following acute infection. Clin Infect Dis. 41(8): 1201-3. Epub 2005 Sep 2 https://pubmed.ncbi.nlm.nih.gov/16163641II. Lindblom A, Heyman M, Gustafsson I, Norbeck O, Kaldensjö T, Vernby A, Henter JI, Tolfvenstam T, Broliden K (2008). Parvovirus B19 infection in children with acute lymphoblastic leukemia is associated with cytopenia resulting in prolonged interruptions of chemotherapy. Clin Infect Dis. 46(4): 528-36 https://pubmed.ncbi.nlm.nih.gov/18194100III. Gustafsson I, Kaldensjö T, Lindblom A, Norbeck O, Henter JI, Tolfvenstam T, Broliden K (2008). Detection of Parvovirus B19 infection in children with malignant or hematological disorders. [Submitted]IV. Lindblom A, Bhadri V, Söderhäll S, Öhrmalm L, Wong M, Lindau C, Rotzen-Östlund M, Allander T, Catchpoole D, Dalla-Pozza L, Broliden K, Tolfvenstam T (2008). Respiratory viral infections are the most common findings employing PCR-based diagnostics in children with neutropenia. [Manuscript]</p
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The impact of deregulation and re-regulation on bank efficiency: evidence from Asia
No full textFollowing the 1997 crisis, banking sector reforms in Asia have been characterised by the emphasis on prudential regulation, associated with increased financial liberalisation. Using a panel data set of commercial banks from eight major Asian economies over the period 2001-2010, this study explores how the coexistence of liberalisation and prudential regulation affects banks’ cost characteristics. Given the presence of heterogeneity of technologies across countries, we use a stochastic frontier approach followed by the estimation of a deterministic meta-frontier to provide ‘true’ estimates of bank cost efficiency measures. Our results show that the liberalization of bank interest rates and the increase in foreign banks' presence have had a positive and significant impact on technological progress and cost efficiency. On the other hand, we find that prudential regulation might adversely affect bank cost performance. When designing an optimal regulatory framework, policy makers should combine policies which aim to foster financial stability without hindering financial intermediation
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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