145 research outputs found
Measurements of laminar burning velocities and an improved kinetic model of methyl isopropyl ketone
Methyl isopropyl ketone (MIPK) is the simplest branched ketone and a promising biofuel. In this work, laminar burning velocities (SL) of MIPK + air flames were measured using the heat flux method at atmospheric pressure, over initial mixture temperatures of 298–358 K and equivalence ratios of 0.7–1.4. With the help of the temperature dependence of the SL, data inconsistency between the present measurements and the experimental data reported by Li et al. (Proc. Combust. Inst. 38 (2021) 2135) was demonstrated. Moreover, existing kinetic models for MIPK combustion notably deviate from the present SL measurements. Therefore, the MIPK model suggested by Lin et al. (Proc. Combust. Inst. 39 (2023) 315) was updated by revisiting the MIPK H-abstraction reactions and methyl isopropenyl ketone sub-model. Furthermore, a new di-methyl ketene (critical intermediate during MIPK oxidation) sub-model was constructed and integrated into the MIPK model. Flux and sensitivity analyses revealed that integration of the new di-methyl ketene model improves predictions of the laminar burning velocities as well as shock tube ignition delay times over the pressures of 1–40 bar due to converting di-methyl ketene into C3H5-T (CH2 = C˙CH3) rather than C3H6 or C3H5-S (C˙H = CHCH3) predicted by other MIPK models from the literature. Updates of the MIPK H-abstraction reactions yield more reasonable products branching ratios of formation of the primary fuel radicals, and improve prediction of the SL. It was also found that the rate constants of the MIPK decomposition reaction (MIPK (+M) = CH3CO + IC3H7 (+M)) in the model proposed by Li et al. (Proc. Combust. Inst. 38 (2021) 2135) are significantly underestimated, resulting in underestimation of the present SL measurements and significant overprediction of the ignition delay times
Investigating the Users' Satisfaction on Intergenerational Co-living Social Housing
This research mainly wants to understand the user\ue2s satisfaction and implementation effect of Qianjin District intergenerational co-living social housing in Kaohsiung City, as well as the management implications of intergenerational co-living social housing. Through investigating young people and silver-haired people living in social housing , to achieve the purpose of the research. There are 48 households in the intergenerational co-living social housing in Qianjin District. After deducting 1 young household who have just moved out and 1 reserved household, the social housing\ue2s space is 100% full. The application status is very active. There are static activities, hospital lectures, rhythmic dance, music singing in the social housing. The elders and the younger generation will help each other and look after children with each other. Such mutual assistance between the old and the young is the daily life of this social housing, forming a positive mutual aid cycle. Most of the community activities are participated by the intergenerational generation, which shows that the interaction between the intergenerational generation in the social housing is good.
The functional aspects of the social housing (indoor ventilation, lighting, equipment conditions, life functions around the social housing, community care centers, and designated nursery service spaces) are generally highly satisfied by the residents (up to 90%), showing that implementation of intergenerational co-living social housing works well in Kaohsiung City.
Intergenerational co-living social housing in Kaohsiung City is a brand-new attempt, which is helpful to improve the social problems of aging. For example, because the youth and the silver-haired people carry out community activities in social housing together, the young people can learn the attitude of being a person and doing things from the elders. The elders also compensate for the lonely side of the aging society because of the company of the young people, and they can also acquire novel concepts and ideas through the process of chatting with the youth group. Such spiritual complementarity cannot be satisfied in normal collective housing.
The contribution of this paper in management practice is to find out that the needs of the young households and the evergreen households for the function of the social housing are quite different. The young households focus on the function of the social housing, such as childcare services, kindergartens, cultural and recreational spaces, social welfare institutions, and community open green spaces; Evergreen households focus on social welfare institutions, long-term care institutions, community activity centers, cultural and recreational spaces, and small medical institutions for the functions of social housing. The social housing management unit can take into consideration the needs of residents of different age groups in the stage of planning the functions of the social housing
Restoration of Kaohsiung QianJin District's Prosperity: A Proposal Based on Local Observation
The author moved from Hengchuen, south of the Taiwan, to the prosperous and gorgeous political and economic center of Kaohsiung City when she was a teenager. The Chiengin District used to be the sub-core of Kaohsiung City's politics, finance, and culture. The riverside scenery of the Love River is the memory of many Kaohsiung people; 2021 The fire incident has aroused the citizens of the Chiengin District to pay attention to housing safety, housing justice, urban renewal, and issues, and to think deeply about economic and cultural planning. Facing the loss of population, lack of economic momentum, and continuous decline , the author selects the historical background, current situation and initiatives of the Chiengin District, and interviews government executives, public opinion representatives, and business scholars by means of in-depth investigation. Profound local observations come up with solutions. It is hoped that in the future, through civic participation, community development associations, and the cohesion of public opinion, we will participate in the layout of urban plans, promote urban development, land activation, and jointly promote cultural governance in the Chiengin District. Let Chiengin District connect the technology corridor of North Kaohsiung and Kaohsiung port with "cultural corridor" to gorgeous turn, graceful reproduction
Long noncoding RNA LINC00261 regulates endometrial carcinoma progression by modulating miRNA/FOXO1 expression
Measurements of laminar burning velocities and an improved kinetic model of methyl isopropyl ketone [Elektronisk resurs]
Methyl isopropyl ketone (MIPK) is the simplest branched ketone and a promising biofuel. In this work, laminar burning velocities (SL) of MIPK + air flames were measured using the heat flux method at atmospheric pressure, over initial mixture temperatures of 298–358 K and equivalence ratios of 0.7–1.4. With the help of the temperature dependence of the SL, data inconsistency between the present measurements and the experimental data reported by Li et al. (Proc. Combust. Inst. 38 (2021) 2135) was demonstrated. Moreover, existing kinetic models for MIPK combustion notably deviate from the present SL measurements. Therefore, the MIPK model suggested by Lin et al. (Proc. Combust. Inst. 39 (2023) 315) was updated by revisiting the MIPK H-abstraction reactions and methyl isopropenyl ketone sub-model. Furthermore, a new di-methyl ketene (critical intermediate during MIPK oxidation) sub-model was constructed and integrated into the MIPK model. Flux and sensitivity analyses revealed that integration of the new di-methyl ketene model improves predictions of the laminar burning velocities as well as shock tube ignition delay times over the pressures of 1–40 bar due to converting di-methyl ketene into C3H5-T (CH2 = C˙CH3) rather than C3H6 or C3H5-S (C˙H = CHCH3) predicted by other MIPK models from the literature. Updates of the MIPK H-abstraction reactions yield more reasonable products branching ratios of formation of the primary fuel radicals, and improve prediction of the SL. It was also found that the rate constants of the MIPK decomposition reaction (MIPK (+M) = CH3CO + IC3H7 (+M)) in the model proposed by Li et al. (Proc. Combust. Inst. 38 (2021) 2135) are significantly underestimated, resulting in underestimation of the present SL measurements and significant overprediction of the ignition delay times
Coupled strategy based on regulator manipulation and medium optimization empowers the biosynthetic overproduction of lincomycin
The biosynthesis of bioactive secondary metabolites, specifically antibiotics, is of great scientific and economic importance. The control of antibiotic production typically involves different processes and molecular mechanism. Despite numerous efforts to improve antibiotic yields, joint engineering strategies for combining genetic manipulation with fermentation optimization remain finite. Lincomycin A (Lin-A), a lincosamide antibiotic, is industrially fermented by Streptomyces lincolnensis. Herein, the leucine-responsive regulatory protein (Lrp)-type regulator SLCG_4846 was confirmed to directly inhibit the lincomycin biosynthesis, whereas indirectly controlled the transcription of SLCG_2919, the first reported repressor in S. lincolnensis. Inactivation of SLCG_4846 in the high-yield S. lincolnensis LA219X (LA219XΔ4846) increases the Lin-A production and deletion of SLCG_2919 in LA219XΔ4846 exhibits superimposed yield increment. Given the effect of the double deletion on cellular primary metabolism of S. lincolnensis, Plackett-Burman design, steepest ascent and response surface methodologies were utilized and employed to optimize the seed medium of this double mutant in shake flask, and Lin-A yield using optimal seed medium was significantly increased over the control. Above strategies were performed in a 15-L fermenter. The maximal yield of Lin-A in LA219XΔ4846-2919 reached 6.56 g/L at 216 h, 55.1 % higher than that in LA219X at the parental cultivation (4.23 g/L). This study not only showcases the potential of this strategy to boost lincomycin production, but also could empower the development of high-performance actinomycetes for other antibiotics
New advances in oil and gas survey of the Qianjin depression in Sanjiang basin, north china
Effect of polyvinyl alcohol/nano-carbon colloid on the electrochemical performance of negative plates of lead acid battery
Polyvinyl alcohol/nano-carbon colloid (PCC) was prepared through a simple physical mixture process. Both fully charge-discharge and insufficient charge tests were carried out to demonstrate the positive effects of PCC on the electrical storage capability of the negative electrode of lead acid battery. Cyclic voltammetry, steady polarization and electrochemical impedance spectroscopy were used to characterize the influences of PCC on the electrochemical behaviors of negative electrode in the lead acid battery. Experiment results demonstrate that PCC has positive effect on inhibiting PbSO growth and increasing the HER overpotential, thus the lead acid battery with PCC shows the enhanced charge acceptance and stable discharge capacities under insufficient charge test. This paper opens a new way for enhancing the performance of lead acid battery without changing the traditional structure and design of lead acid battery.The research group acknowledges the financial support provided by National Natural Science Foundation of China (No. 21573093), the National Key Research and Development Program (No. 2017YFB0307501), Guangdong Innovative and Entrepreneurial Research Team Program (No. 2013C092) and the Graduate Innovation Fund of Jilin University (No. 2015141)
Clusterin silencing inhibits proliferation and reduces invasion in human laryngeal squamous carcinoma cells
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