1,516,943 research outputs found
A comment on "Intergenerational equity: sup, inf, lim sup, and lim inf"
No full textWe reexamine the analysis of Chambers (Social Choice and Welfare, 2009), that produces a characterization of a family of social welfare functions in the context of intergenerational equity: namely, those that coincide with either the sup, inf, lim sup, or lim inf rule. Reinforcement, ordinal covariance, and monotonicity jointly identify such class of rules. We show that the addition of a suitable axiom to this three properties permits to characterize each particular rule. A discussion of the respective distinctive properties is provided.Social welfare function; Intergenerational equity; Lim sup ; Lim inf
Multiple functions of LIM domain-binding CLIM/NLI/Ldb cofactors during zebrafish development
No full textThe crucial involvement of CLIM/NLI/Ldb cofactors for the exertion of the biological activity of LIM homeodomain transcription factors (LIM-HD) has been demonstrated. In this paper we show that CLIM cofactors are widely expressed during zebrafish development with high protein levels in specific neuronal cell types where LIM-HD proteins of the Isl class are synthesized. The overexpression of a dominant-negative CLIM molecule (DN-CLIM) that contains the LIM interaction domain (LID) during early developmental stages of zebrafish embryos results in an impairment of eye and midbrain-hindbrain boundary (MHB) development and disturbances in the formation of the anterior midline. On a cellular level we show that the outgrowth of peripheral but not central axons from Rohon Beard (RB) and trigeminal sensory neurons is inhibited by DN-CLIM overexpression. We demonstrate a further critical role of CLIM cofactors for axonal outgrowth of motor neurons. Additionally, DN-CLIM overexpression causes an increase of Isl-protein expression levels in specific neuronal cell types, likely due to a protection of the DN-CLIM/LIM-HD complex from proteasomal degradation. Our results demonstrate multiple roles of the CLIM cofactor family for the development of entire organs, axonal outgrowth of specific neurons and protein expression levels
Four and a half LIM protein 1C (FHL1C)
No full textFour-and-a-half LIM domain protein 1 isoform A (FHL1A) is predominantly expressed in skeletal and cardiac muscle. Mutations in the FHL1 gene are causative for several types of hereditary myopathies including X-linked myopathy with postural muscle atrophy (XMPMA). We here studied myoblasts from XMPMA patients. We found that functional FHL1A protein is completely absent in patient myoblasts. In parallel, expression of FHL1C is either unaffected or increased. Furthermore, a decreased proliferation rate of XMPMA myoblasts compared to controls was observed but an increased number of XMPMA myoblasts was found in the G(0)/G(1) phase. Furthermore, low expression of K(v1.5), a voltage-gated potassium channel known to alter myoblast proliferation during the G(1) phase and to control repolarization of action potential, was detected. In order to substantiate a possible relation between K(v1.5) and FHL1C, a pull-down assay was performed. A physical and direct interaction of both proteins was observed in vitro. In addition, confocal microscopy revealed substantial colocalization of FHL1C and K(v1.5) within atrial cells, supporting a possible interaction between both proteins in vivo. Two-electrode voltage clamp experiments demonstrated that coexpression of K(v1.5) with FHL1C in Xenopus laevis oocytes markedly reduced K(+) currents when compared to oocytes expressing K(v1.5) only. We here present the first evidence on a biological relevance of FHL1C
Omaggio a Wojtyla
No full textQuesto progetto è nato in seguito allʼincidente automobilistico che H.H. Lim ebbe in autostrada mentre il 26 marzo 2005 si recava da Roma a Napoli per lʼapertura della mostra inaugurale del PAN - Palazzo delle Arti di Napoli, The Giving Person. Il dono dell'artista, a cura di Lóránd Hegyi, invitato dallʼartista Yan Pei Ming che pochi giorni prima aveva visitato la personale di Lim presso Fondazione Volume! A Roma. Lim ne uscì infatti - nonostante la gravità dellʼincidente - illeso e decise di continuare fino alla mostra abbandonando lʼautomobile distrutta in autostrada. Una serie di segni già prima della partenza e durante il viaggio - lʼopera esposta in mostra dallʼamico Yan Pei Ming, una grande figura di Buddha rossa, simile a quella che Lim da sempre al collo e la morte del pontefice pochi giorni dopo - hanno portato lʼartista a sviluppare questo progetto, corrispondente a un lavoro mai realizzato in quanto rimasto sempre nella forma di un pensiero.
Come ringraziamento Lim decise infatti di immaginare una grande mostra pubblica per ringraziare il Papa: il lavoro consiste in una serie di fotomontaggi realizzati attraverso Photoshop, che mostrano alcuni disegni di Lim - riconducibili alla serie di lavori Words - sovrapposti alle prime pagine dei giornali e affissi durante i funerali di Wojtyla, che si svolsero l'otto aprile 2005 in Piazza San Pietro.This project was born in the aftermath of HH Lim's car accident which occurred on the highway on March 26th in 2005, while he was on his way from Rome to Naples for the opening of the inaugural exhibition of the PAN - Palazzo delle Arti di Napoli, The Giving Person. Il dono dell'artista, curated by Lóránd Hegyi, invited by the artist Yan Pei Ming who had visited Lim's exhibition at Fondazione Volume! in Rome a few days earlier. Despite the severity of the accident, Lim was unharmed and decided to proceed his journey abandoning the destroyed car on the side of the highway. The project was inspired by a series of events that occurred before the departure and during the trip, as well as a work of art by his friend Yan Pei Ming on display in the exhibition - a large red figure of a Buddha, similar to the one Lim has always been wearing on his neck - and ultimately the death of the pope a few days later. The project was never actually developed as it remained a mere thought, an idea the artist had. Lim imagined a large public exhibition to thank the Pope: the work would have consisted of a series of montages made using Photoshop, showing some drawings of Lim – linked to the series of Words - superimposed on the front pages of the newspapers and posted during the funeral of Wojtyla, which took place on April 8th 2005 in the St. Peter's Square
Entrevista a Sean Lim en la Reunión CUDI, otoño 2013
No full textEntrevista con Sean Lim durante la Reunión CUDI, otoño 2013.Entrevista con Sean Lim, Vicepresidente mundial de EC - Council.13_10_02_sean_lim.fl
ARTICLES, REPORTS AND SPEECHES, 1998-2008 - Lectures - Lim Lecture, 2007
No full textLecture from CJ Lim on September 11, 2007.http://deepblue.lib.umich.edu/bitstream/2027.42/118142/2/39015094711705.mp4http://deepblue.lib.umich.edu/bitstream/2027.42/118142/3/39015094711705.zi
Clip from Interview with Melanie Lim
No full textAn excerpt from a video interview with Melanie Lim, part of the Cambodian American Community of Oregon\u27s oral history project documenting the experiences of survivors of the Cambodian genocide of 1975-1979.Interview by Lauro Lim, 29 May 2009.https://pdxscholar.library.pdx.edu/caco_interviews/1004/thumbnail.jp
[Patricio Lim won a gold medal]
No full textPatricio Lim, a third year student in the School of Commerce won a gold medal for himself and a trophy for the school, when he was judged the best speaker of five orators of the leading colleges and universities, in a forum sponsored by the Rotary Club. He spoke on the Moral aspect of the Japanese Peace Treaty
Mee-Gaik Lim
No full textA black and white negative of professor Mee-Gaik Lim, Counseling & Guidance faculty.https://lair.etamu.edu/scua-univ-photos-browse-all/2890/thumbnail.jp
Epanerchodus gangwonus Mikhaljova & Lim 2002
No full textEpanerchodus gangwonus Mikhaljova & Lim, 2002 Epanerchodus gangwonus Mikhaljova & Lim, 2002: 19 –21, 20: figs 1–8. Remarks. Originally described from Gangwon-do, South Korea (Mikhaljova & Lim, 2001), this species has since never been rediscovered. Distribution. South Korea.Published as part of M, E L E N A V., Va, I K H A L J O & Lim, Kil-Young, 2006, The millipede genus Epanerchodus Attems, 1901 in the Korean Peninsula, with a description of a new species (Diplopoda, Polydesmida, Polydesmidae), pp. 45-53 in Zootaxa 1350 on page 48, DOI: 10.5281/zenodo.17451
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