1,415 research outputs found

    Ingrid Ylva och tornet i Bjälbo

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    The article discusses the background to the erection of the huge church tower in Bjälbo, Östergötland, Sweden. It also focuses on medieval women as founders of churches. The author maintains that new dendrochronological dating of the tower could mean that founder of this building piece was not one of the male members of the important Bjälbo dynasty, but Ingrid Ylva the mother of Birger Jarl

    HOMA-IR and the Matsuda Index as predictors of progression to type 1 diabetes in autoantibody-positive relatives

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    Aim/hypothesis We assessed whether HOMA-IR and the Matsuda Index are associated with transitions through stages of type 1 diabetes.Methods Autoantibody (AAb)-positive relatives of individuals with type 1 diabetes (n=6256) from the TrialNet Pathway to Prevention were studied. Associations of indicators of insulin resistance (HOMA-IR) and insulin sensitivity (Matsuda Index) with BMI percentile (BMIp) and age were assessed with adjustments for measures of insulin secretion, Index60 and insulinogenic index (IGI). Cox regression was used to determine if tertiles of HOMA-IR and Matsuda Index predicted transitions from Not Staged (= 2 AAbs and normoglycaemia), from Stage 1 to Stage 2 (>= 2 AAbs with dysglycaemia), and progression to Stage 3 (diabetes as defined by WHO/ADA criteria).Results There were strong associations of HOMA-IR (positive) and Matsuda Index (inverse) with baseline age and BMIp (p<0.0001). After adjustments for Index60, transitioning from Stage 1 to Stage 2 was associated with higher HOMA-IR and lower Matsuda Index (HOMA-IR: HR=1.71, p<0.0001; Matsuda Index, HR=0.40, p<0.0001), as with progressing from Stages 1 or 2 to Stage 3 (HOMA-IR: HR=1.98, p<0.0001; Matsuda Index: HR=0.46, p<0.0001). Without adjustments, associations of progression to Stage 3 were inverse for HOMA-IR and positive for Matsuda Index, opposite in directionality with adjustments. When IGI was used in place of Index60, the findings were similar.Conclusions/interpretation Progression to Stages 2 and 3 of type 1 diabetes increases with HOMA-IR and decreases with the Matsuda Index after adjustments for insulin secretion. Indicators of insulin secretion appear helpful for interpreting associations of progression to type 1 diabetes with HOMA-IR or the Matsuda Index in AAb-positive relatives

    Ingrid Winterbach: Novelist (Interview)

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    Winner of the prestigious Hertzog Prize for Literature for Niggie (2002)Ingrid Winterbach is the author of eight novels, three of which have been translated into English and two into Dutch. The translation of her fourth novel, Karolina Ferreira (1993) as The Elusive Moth (2005), and subsequently, Niggie as To Hell with Cronjé (2007) and Die boek van toeval en toeverlaat (2006) as The Book of Happenstance (2008), have brought this author to the attention of a wider South African readership

    7. When They Left

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    Figure 7.1 The author, Ingrid Griffith (right) with her sister Dawn (left) and brother Oliver (center) in December 1968. Their maternal grandmother had taken them to Skevelair’s Photo Studio in Georgetown, Guyana to pose in the church outfits their parents, who had recently migrated to the United States, had sent for Christmas. © Griffith Family Collection. Courtesy of Ingrid Griffith. CC BY 4.0. It was one of the worst days of my life. I was seven years old, my sist..

    270 - Ingrid Jane Slette

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    Global climate change is causing more extreme droughts, as well as subtler chronic changes in precipitation patterns. Both chronic and extreme precipitation change can alter ecosystem structure and function, and these alterations may affect how systems respond to future extreme climatic events. Understanding how legacies of various past precipitation changes may alter the effects of future extreme droughts will be important for predicting ecosystem responses to climate change. We investigated how ecological legacies of experimentally-imposed chronic and extreme precipitation changes altered the impact of an extreme drought on an economically-important grassland ecosystem.Top Scholars for University-Wide Graduate Programs

    Funktionelle Analyse von potententiell aktivierenden FGFR3 Mutationen

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    Author Ingrid Hartl, MScAbweichender Titel laut Übersetzung der Verfasserin/des VerfassersDissertation Johannes Kepler Universität Linz 2022Arbeit nach Ablauf der Sperre auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba

    Resensies: Vlam in die sneeu. Die liefdesbriewe van André P. Brink en Ingrid Jonker

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    Book Title: Vlam in die sneeu. Die liefdesbriewe van André P. Brink en Ingrid JonkerBook Author: Francis Galloway (red.)Kaapstad: Umuzi, 2015. 450 pp. ISBN: 978-1-4152-0881-6. Spesiale uitgawe ISBN: 978-1-4152-0893-9

    Arboviral Disease Surveillance, Kansas, 2014

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    "Report Author: Ingrid C. Garrison"--Page 18.; "April 21, 2016."; Includes bibliographical and internet references (page 12)."Arboviruses (arthropod-borne virus) are commonly spread to humans through the bites of infected mosquitoes, ticks, sand flies, or midges. This report focuses on those arboviruses transmitted by mosquitoes. West Nile virus is the leading cause of domestically acquired arboviral disease in the United States and Kansas.

    VI Curso Internacional de Endocrinología, Diabetes y Metabolismo

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    Diabetes en niños y adolescentes - no es solo diabetes tipo 1 o tipo 2 Ingrid Libman, Md, Phd La diabetes mellitus (DM) en la infancia y adolescencia constituye un espectro. Si bien la DM tipo 2 (DM2) es la forma más frecuente en la población en general, la DM tipo 1 (DM1) constituye el tipo más común en la niñez y juventud. Más del 50% de los enfermos afectados con DM1 son diagnosticados durante los primeros años de vida. En la mayoría de los países occidentales, la DM1 constituye más del 90% de los casos diagnosticados en la infancia y adolescencia. La DM2 era considerada hasta hace poco tiempo una enfermedad propia de la edad adulta. Si bien es cierto que continúa siendo más prevalente en este grupo etario, existe evidencia de su aparición con mayor frecuencia en la adolescencia y juventud, en estrecha asociación con el aumento en la prevalencia de la obesidad. La etiología de la DM2 es multifactorial, incluyendo factores genéticos y ambientales, resultando de la combinación de un aumento de la resistencia a la insulina en los tejidos periféricos asociado al incremento del tejido adiposo visceral y a una disfunción progresiva de las células ?. Por otra parte, una forma con características de ambos tipos, conocida como diabetes “doble” o “híbrida” ha sido descrita más recientemente, Estos jóvenes se presentan con un fenotipo que incluye manifestaciones de la DM2 (obesidad, presencia de acantosis nigricans) al mismo tiempo que muestran evidencia de autoinmunidad dirigida a las células ?, ya sea la presencia de anticuerpos o una respuesta anormal de los linfocitos a antígenos celulares de los islotes, indicadores de DM1
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