185 research outputs found
Rationalisation of the Tsai-Wu failure criterion
No full textThe objective of this paper is to rationalise the empirical aspect of the Tsai-Wu failure criterion associated with the determination of the interactive strength property F12 based on the analytical geometry according to which the condition of closed failure envelope cannot be satisfied by all unidirectionally fibre reinforced composites (UD) and hence should be abandoned. Depending on the way the failure envelope opens, UD composites can be classified into two categories. (a) F12 can be determined uniquely using the conventional strength properties with an additional assumption that the material exhibit very high or infinite strength under triaxial compression at a specific stress ratio; or (b) The Tsai-Wu criterion lead to one of the two scenarios: either allowing infinite strength for an in-plane stress state or to allow infinite strength under infinite number of triaxial stress ratios, some involving tension along fibres. The rationalisation supplements the existing understanding with generic facts which have hitherto not been revealed. The validity of the new assumption can only be proven by experiments which are scarce. A call for relevant experimental data is generated though this paper in order to assess the likelihood of very high or infinite strength.</p
The Tsai-Wu failure criterion rationalised in the context of UD composites
No full textThis paper is to rationalise the empirical aspect of the Tsai-Wu failure criterion in the context of UD composites associated with the determination of the interactive strength property F12 based on the analytic geometry. It reveals that the condition of closed failure envelope cannot be satisfied by all UD composites and hence the restriction should be abandoned. Depending on the way the failure envelope opens, UD composites can be classified into two categories. (a) F12 can be determined uniquely using the conventional strength properties with an additional assumption that the material exhibits very high or infinite strength under triaxial compression at a specific stress ratio; or (b) The Tsai-Wu criterion leads to one of the two scenarios: either allowing infinite strength for an in-plane stress state or allowing infinite strength under triaxial stresses involving tension along fibres
Author Correction: A shared neural basis underlying psychiatric comorbidity
No full textCorrection to: Nature Medicine. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Hervé Lemaître, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris and Sylvane Desrivières. The STRATIFY and ESTRA consortia are now combined to list Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Gareth J. Barker, Arun L. W. Bokde, Hervé Lemaître, Frauke Nees, Dimitri Papadopoulos Orfanos, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris, Henrik Walter, Robert Whelan, Sylvane Desrivières and Gunter Schumann as members, and the IMAGEN consortium is updated to also include Sylvane Desrivières. Affiliations, author contributions and acknowledgements have been updated to reflect the new authorship, and all changes have been made in the HTML and PDF versions of the article
Author Correction: A shared neural basis underlying psychiatric comorbidity
No full textCorrection to: Nature Medicine https://doi.org/10.1038/s41591-023-02317-4. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Hervé Lemaître, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris and Sylvane Desrivières. The STRATIFY and ESTRA consortia are now combined to list Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Gareth J. Barker, Arun L. W. Bokde, Hervé Lemaître, Frauke Nees, Dimitri Papadopoulos Orfanos, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris, Henrik Walter, Robert Whelan, Sylvane Desrivières and Gunter Schumann as members, and the IMAGEN consortium is updated to also include Sylvane Desrivières. Affiliations, author contributions and acknowledgements have been updated to reflect the new authorship, and all changes have been made in the HTML and PDF versions of the article.</p
From the headwater to the delta: A synthesis of the basin-scale sediment load regime in the Changjiang River
No full textMany large rivers in the world delivers decreasing sediment loads to coastal oceans owing to reductions in sediment yield and disrupted sediment deliver. Understanding the sediment load regime is a prerequisite of sediment management and fluvial and deltaic ecosystem restoration. This work examines sediment load changes across the Changjiang River basin based on a long time series (1950–2017) of sediment load data stretching from the headwater to the delta. We find that the sediment loads have decreased progressively throughout the basin at multiple time scales. The sediment loads have decreased by ~96% and ~74% at the outlets of the upper basin and entire basin, respectively, in 2006–2017 compared to 1950–1985. The hydropower dams in the mainstem have become a dominant cause of the reduction, although downstream channel erosion causes moderate sediment load recovery. The basin-scale sediment connectivity has declined as the upper river is progressively dammed, the middle-lower river is leveed and river-lake interplay weakens. The middle-lower river has changed from a slight depositional to a severe erosional environment, from a sediment transport conduit to a new sediment source zone, and from a transport-limited to a supply-limited condition. These low-level sediment loads will likely persist in the future considering the cumulative dam trapping and depleted channel erosion. As a result, substantial hydro-morphological changes have occurred that affect the water supply, flood mitigation, and the aquatic ecosystem. The findings and lessons in this work can shed light on other large river systems subject to intensified human interference.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Coastal Engineerin
Rezension/Review/Mapitio: Yuning Shen. 2018. Transitivität und Verbvalenz im Swahili. [Transitivity and Verb Valence in Swahili/Uelekezi na Mpangilio wa Vitenzi katika Lugha ya Kiswahili]. Köln: Rüdiger Köppe, 104 pp., ISBN 978-3-89645-712-7.
No full textYuning Shen’s study deals with transitivity and verb valency in Kiswahili using a corpus-based approach. The author relates the methods used and results with previous studies dealing with the same topic, namely Whiteley (1968), Abdulaziz (1996) and Olejarnik (2005). He uses the meta-function-rank-matrix (MF/R) from Chinese to point out the fallacy of adopting such a matrix from one language and imposing it on another. Using the parts of speech annotation TreeTagger (Schmid 1994, 1995) to examine previous verb classifications, the author discusses the divergent use of concepts such as verb radicals, verb stems and verb bases as used in different theoretical approaches.Kitabu hiki cha Yuning Shen kinahusu uelekezi na mpangilio wa vitenzi katika lugha ya Kiswahili kwa kutumia mkabala wenye msingi wa kopasi ya kiisimu. Mwandishi anazihusisha mbinu zilizotumika na matokeo yake na kazi za utafiti zilizotangulia zilizoshughulikia mada hiyo yaani Whiteley (1968), Abdulaziz (1996), na Olejarnik (2005). Shen anatumia mkabala wa mpangilio wa viwango tofauti vya matumizi ya lugha (meta-function-rank-matrix, MF/R) iliyotumika kwa utafiti wa lugha ya Kichina kwa ajili ya kuonesha udhaifu wa mkabala huo kwani unaiga mfumo unaofanya kazi katika lugha moja na kuutumia kwa lugha nyingine bila kuzingatia kuwa lugha ni tofauti. Kwa kutumia njia ya matawi ya kutenganisha vipashio vya maneno (TreeTagger) iliyobuniwa na Schmid (1994, 1995) kwa lengo la kuchunguza njia za awali za kuainisha vitenzi, mwandishi anayajadili matumizi yanayotofautiana ya dhana mbalimbali kama vile viini vya vitenzi, mashina ya vitenzi, na mizizi ya vitenzi jinsi ambavyo zimetumika katika mikabala mbalimbali ya kinadharia
Advances in the Drug Delivery Systems for Psoriasis Topical Therapy
No full textYang Liu,1,&ast; Ruizhen Chang,2,&ast; Huan Deng,2 Feiqing Liang,2 Xi Xu,2 Yuning Luo2 1Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, People’s Republic of China; 2Shenzhen Longgang Second People’s Hospital, Shenzhen, Guangdong, 518112, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xi Xu, Shenzhen Longgang Second People’s Hospital, Shenzhen, Guangdong, 518112, People’s Republic of China, Email [email protected] Yuning Luo, Shenzhen Longgang Second People’s Hospital, Shenzhen, Guangdong, 518112, People’s Republic of China, Email [email protected]: Psoriasis (PSO) is an immune-related skin disease featured by rapid and excessive cell growth leading to thick red scaly skin plaques. The main treatment strategy for PSO involves using anti-inflammatory drugs, immunosuppressants, etc, to relieve symptoms, suppress inflammation, and retard the overgrowth and division of skin cells. However, these drugs generally have disadvantages such as poor targeting, short half-life, low bioavailability, significant toxic side effects, etc. which impose a huge physiological and pathological burden on patients. Recently, the use of delivery systems to topical deliver drugs to the damaged psoriatic skin sites has received extensive attention from researchers. These systems promote drug stability, enhance drug penetration, and improve drug efficacies. The continuous development of various multifunctional topical delivery systems provides more therapeutic ideas for the cure of PSO. Based on this, this manuscript reviews the research progress of various delivery systems (including nanoparticles, hydrogels, microneedles, micelles, dendrimers, liposomes, nanoemulsions, vesicles, etc.) for PSO topical therapy and summarizes their development status in clinical treatment. It’s expected to provide reference for the design of novel topical delivery systems and promote the development of PSO therapy methods.Keywords: psoriasis, drug carrier, drug delivery, topical therap
Enterprise architecture modeling for cybersecurity analysis in critical infrastructures — A systematic literature review
No full textAs digital landscapes become increasingly complex, safeguarding sensitive information and systems against cyber threats has become a paramount concern for organizations. This paper provides a comprehensive review of how enterprise architecture modeling is used in the context of cybersecurity assessment, particularly focusing on critical infrastructures. The use of enterprise architecture models for cybersecurity is motivated by the main purpose of enterprise architecture, namely to represent and manage business and IT assets and their interdependence. While enterprise architecture modeling originally served to assess Business/IT alignment, they are increasingly used to assess the cybersecurity of the enterprise. The research questions explored include the types of enterprise architecture models used for cybersecurity assessment, how security aspects are incorporated into these models, the theoretical frameworks and reference theories applied, the research methods used for evaluation, and the strengths and limitations of these models in supporting cybersecurity assessment. This review encompasses research papers published before 2024, focusing on high-quality research from peer-reviewed journals and reputable conferences, thereby providing a structured and comprehensive overview of the current state of research in this domain.CC BY-NC 4.0Corresponding author: Yuning JiangE-mail addresses: [email protected]</p
Structure from constrained motion
No full textStructure reconstruction has been studied extensively over the past decade by many researchers in computer vision. The focus of this thesis is on the research and development for reconstructing the 3D structure from camera motion. Finding the correspondences between two perspective views is a necessary first step in structure reconstruction. In this work, point features are consid-ered. An extensive review on the point feature descriptors is presented as a good preparation for further processes. Furthermore, the correspondences be-tween the point features in two views are established by using correlation based technique together with simple interframe tracking.Master of Engineerin
Quantum Control of Interacting Spins
No full textQuantum decoherence is one of the most substantial challenges on the way to fullyfledged quantum technology. Noise mitigation based on dynamical control techniques, aside from error correction, is known to be another effective approach to protect qubits from decoherence. In this thesis, we studied the dynamics of a spin qubit interacting with a disordered spin bath in different dimensions. By modeling the environmental spins from fundamental dipolar couplings and employing Monte-Carlo simulations, this research provides an insight into the precise driving and control of a noisy spin qubit, including the noise distribution, decoherence mechanism, driving error, gate fidelity, and performance of dynamical decoupling sequence. This knowledge will be helpful to the future design of noise-robust quantum gates and potential decoupling protocols of spin qubits.https://github.com/Neuromancer43/SpinControl.jl Software PackageApplied Physic
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