1,720,966 research outputs found
Prediction of Compensated Liver Cirrhosis by Ultrasonography and Routine Blood Tests in Patients with Chronic Viral Hepatitis
No full text학위논문(석사)--아주대학교 일반대학원 :의학과,2011. 2배경: 현재 간경변증을 진단하기 위해서 간 조직 검사가 표준 방법으로 되어있으나 간 조직 검사는 침습적인 방법으로 일부의 환자에서만 시행되고 있다. 보통 일반 혈액 검사와 초음파 검사를 시행하여 간경변증을 진단하고 있다. 이에 이번 연구는 만성 B형 및 C형 바이러스 간염 환자를 대상으로 초음파 검사와 일반혈액검사를 통한 대상성 간경변증의 진단 정확도를 알아보고자 하였다.
대상 및 방법: 아주대병원에 내원하여 복부 초음파 검사 와 혈액 검사 및 조직 검사를 시행한 만성 B형 및 C형 바이러스 간염 환자 203명을 대상으로, 초음파 검사 와 일반혈액검사를 통한 대상성 간경변증의 진단 정확도를 알아보기 위해서 간 조직 검사 결과와 다변량 및 교차 분석 실시하였다.
결과: 로지스틱 회귀 분석 결과 간표면 결절성이 간경변증의 진단에 의미 있게 영향을 미치며 교차비가 12.645로 높았고 혈소판수가 100,000/uL 이하로 잡았을 때는 유의한 값을 얻지 못했으나 120,000/uL 이하인 것과 알부민 수치가 3.5 g/dL 이하로 했을 때는 유의하게 영향을 미치고 각각의 교차비는 4.575 와 12.409였다. 교차분석 결과 혈소판100,000/uL이하, 알부민 3.5g/dL이하, 프로트롬빈시간(INR) 1.3이상, 간 표면 결절화가 있는 경우는 각각 특이도가 95% 이상으로 매우 높았다. 교차 분석에서 특이도가 높았던 초음파상 간 표면 결절성이 있고, 100,000 /uL이하의 혈소판, 3.5 g/dL이하의 알부민, 1.3이상의 프로트롬빈시간(INR) 중에 하나만 만족하는 교차분석 에서 90.42%의 높은 특이도를 보이면서도 61.11%의 비교적 높은 민감도를 보였다.
결론: 만성 간질환 환자에서 초음파로 간 표면 결절성 소견이 보이거나 혈소판이 100,000/uL이하이거나 알부민 3.5g/dL 이하, 또는 프로트롬빈시간(INR)이 1.3이상인 경우는 비교적 높은 특이도로 대상성 간경변증을 진단할 수 있었다.ABSTRCT ⅰ
TABLE OF CONTETS ⅲ
TABLE OF TABLES iv
Ⅰ. INTRODUCTION 1
Ⅱ. PATIENTS AND METHODS 3
A. Patients 3
B. abdominal ultrasonography 5
C. liver biopsy 6
D. data analysis 6
Ⅲ. RESULTS 7
A. The interobserver agreement of ultrasonographic findings 7
B. Blood tests and ultrasonographic variables in the diagnosis of compensated liver cirrhosis 7
C. The usefulness of each variable in the diagnosis of compensated liver cirrhosis 11
Ⅳ. DISCUSSION 14
Ⅴ. CONCLUSION 18
REFERENCES 19
국문요약 23MasterBackground: A liver biopsy is the standard method for the diagnosis of liver cirrhosis in patients with chronic hepatitis. Because the liver biopsy is an invasive method, non-invasive methods have been used to diagnose compensated liver cirrhosis in patients with chronic hepatitis. The current study was designed to evaluate ultrasonography and routine blood tests for diagnosing compensated liver cirrhosis in patients with chronic viral hepatitis.
Materials and methods: Two hundred three patients with chronic viral hepatitis who underwent liver biopsy were included in this study and ultrasonography and routine blood tests were analyzed retrospectively. Ultrasonographic findings, such as surface nodularity, parenchyma echogenecity, and spleen size, were evaluated. The diagnostic accuracy of ultrasonography and routine blood tests were examined.
Results: Discriminant analysis with forward stepwise selection of the variables showed that liver surface nodularity, platelet count, and albumin level were independently associated with compensated liver cirrhosis (p 95% specificity: platelet count 1.3; and surface nodularity. If at least one of the 4 variables exists in a patient with chronic viral hepatitis, we can predict liver cirrhosis with 90% specificity and 61% sensitivity.
Conclusions: These results suggest that 4 variables (platelet count 1.3, and surface nodularity) can be used to identify liver cirrhosis in patients with chronic viral hepatitis with high specificity
Investigating Series and Parallel Oxide Memtransistors for Tunable Weight Update Properties
No full textCurrently,analog in-memory computing, employing memristorsintoa crossbar array architecture (CAA), is the leading system among availableneuromorphic hardware. This study presents a highly tunable synapticweight update based on a multiterminal memtransistor device as a solutionfor nonlinear synaptic operations and crosstalk issues in CAA memristors,which are long-standing challenges in neuromorphic hardware applications.To explore an effective device structure for tunable weight updateproperties, a memtransistor device with a series and parallel structurefunctioning by interface type and oxygen migration is fabricated usinga ZnO channel layer and an amorphous TiO2 memristor. Theseries memtransistor device exhibits a significant tunable weightupdate property at the gate knob; thus, it simultaneously can functionas a selector (accelerating and inhibiting weight update) in the CAAand tune and ultimately improve the linearity of the potentiationand depression curves. Neuromorphic hardware based on tunable synapticweight update functions provides advantageous features for accuracyand crosstalk issues. Using the Fashion-MNIST pattern recognitionsimulation, the tuned weight update properties are obtained by threedifferent write and read condition combinations, and the results areclose to ideal accuracy
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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