1,721,024 research outputs found

    Studio dell'effetto delle radiazioni non ionizzanti sul processo di maturazione e differenziamento dei granuli cerebellari di ratto neonato: studi in vitro e in vivo

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    The purpose of this study is to examine the effect of Extremely Low Frequency electromagnetic Fields (ELF) on the differentiation of cerebellar granule neurons. These cells represent the main population of the rat cerebellum and is one of the most widespread models for the study of numerous neuronal parameters(Balazs et al.,1988; Gallo et al.,1987; Contestabile 2002). In this research I studied cerebellar granule neurons, in experiments in vitro and in vivo. In the first case I analyzed the effects induced by the exposure to electromagnetic fields on primary cerebellar granule neurons of newborn rats, which were eight days old. In the second case I exposed pregnant rats, for the entire duration of the gestation and I sacrified the newborn rat after eight days of exposure. In both cases the cells exposed to the electromagnet fields of 50 Hz, 1 mT showed one premature reaction to Glutamate toxicity test. Moreover the Patch clamp technique showed an increase of the currents of the KAINATO in the exposed cells. These two techniques showed a premature and greater activity of glutamate receptors in the exposed cells. The study of expression of ionotropic glutamate receptors confirmed, by means of Western blotting and RT-PCR, their precocius expression in the exposed cells. These receptors represent an index of maturation of the cerebellar granule neurons (Hack and Balazs 1994), therefore I studied another important neuronal marker, the protein NF-200, one of the three proteins of the neurofilament. Immunofluorescence assay and Western blotting showed one greater expression of this marker in the exposed cells compared to control cells. All these results indicate that the electromagnetic fields of 50Hz and 1 mT can interact with biological material, in fact in my research I demonstrated that the exposure to this physical agent is able to induce a premature maturation and differentiation of cerebellar granule neurons

    Notes on systematics and chorology of Asparagus L. (Asparagaceae) in Sardinia (Italy)

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    The occurrence in Sardinia (Italy) of Asparagus acutifolius L., A. albus L. and A. horridus L. is here confirmed. The three taxa were studied on material collected from natural populations and specimen from several herbaria (SS, SASSA, CAG, FI and Ancona). Notes on chorology, systematics, ecology and fenology of the mentioned species are given. The exclusion of A. aphyllus L. and the uncertain presence of other taxa related to the A. officinalis L. group, are discussed

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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