148 research outputs found
Jim Al-Khalili: Science & Islam
Jim Al-Khalili Jim Al-Khalili, a professor of theoretical physics at the university of Surrey, is the author of Paradox: The Nine Greatest Enigmas in Physics (Bantam Press, 2012), Pathfinders: The Golden Age of Arabic Science, (Allen Lane, 2010) and Quantum: A Guide for the Perplexed (Weidenfeld & Nicholson, 2003, Phoenix, 2012). In a 3-episode BBC documentary film (2009), Jim Al-Khalili travels through Syria, Iran, Tunisia and Spain to tell the story of the great leap in scientific knowledg..
Jim Al-Khalili: Science & Islam
Jim Al-Khalili Jim Al-Khalili, a professor of theoretical physics at the university of Surrey, is the author of Paradox: The Nine Greatest Enigmas in Physics (Bantam Press, 2012), Pathfinders: The Golden Age of Arabic Science, (Allen Lane, 2010) and Quantum: A Guide for the Perplexed (Weidenfeld & Nicholson, 2003, Phoenix, 2012). In a 3-episode BBC documentary film (2009), Jim Al-Khalili travels through Syria, Iran, Tunisia and Spain to tell the story of the great leap in scientific knowledg..
PANDANGAN PENGARANG DALAM NOVEL KHAN AL-KHALILI KARYA NAGUIB MAHFOUZ (PENELITIAN STRUKTURALISME GENETIK)
Penelitian ini bertujuan untuk mendeskripsikan (1) struktur novel Khan Al-Khalili karya Naguib Mahfouz, (2) Pandangan pengarang yang terdapat di dalam novel “Khan Al-Khalili” karya Naguib Mahfouz melalui teori Pandangan.
Pendekatan yang dilakukan dalam penelitian ini adalah pendekatan strukturalisme genetik. Objek penelitian ini adalah novel “Khan Al-Khalili” karya Naguib Mahfouz. Novel ini diterjemahkan ke dalam bahasa Inggris oleh Roger Allen dan diterbitkan oleh Anchor Books pada tahun 2008. Instrumen dalam penelitian ini adalah human instrument. Data diperoleh dengan teknik membaca dan mencatat. Data dianalisis dengan metode dialektik.
Hasil penelitian menunjukkan (1) terdapat beberapa struktur yang membangun novel “Khan Al-Khalili” karya Naguib Mahfouz ini, antara lain novel ini bertema percintaan dan berlatar tempat di Kairo, Mesir. Sedangkan latar waktunya berlangsung selama satu tahun dimulai dari 1941-1942. Latar sosialnya bisa dilihat dari sikap, status sosial, keyakinan, dan organisasi sosial. Sedangkan tokoh di dalam novel ini terdiri dari Ahmad Akif, Rushdi Akif, dan Nawal yang merupakan tokoh utama. Sedangkan Akif Ahmad Effendi, Sitt Dawlat, Kamal Khalil, Sitt Tauhida, Boss Nunu, dan Ahmad Rashid adalah tokoh tambahan. Novel ini menggunakan alur campuran karena terdapat beberapa adegan kilas balik di ceritanya. Selain itu, sudut pandang yang digunakan dalam novel ini adalah sudut pandang orang ketiga serba tahu. Lalu, amanat yang terdapat dalam novel ini adalah bahwa kita harus bersyukur dengan kehidupan yang kita jalankan dan juga harus menjaga diri sendiri lebih baik lagi dalam perbuatan sehingga tidak ada penyesalan pada kemudian hari.
(2) Pandangan pengarang Naguib Mahfouz dengan novelnya “Khan Al-Khalili” adalah pengarang ingin mengungkapkan kepada pembaca pengaruh Perang II pada masyarakat Kairo dalam segi politik, kehidupan sosial dan budaya, agama, dan ekonomi. Dalam segi politik, terdapat konflik antara ideologi konservatif dengan liberal pada masyarakat Kairo. Dalam segi kehidupan sosial dan budaya, masyarakat Kairo memiliki komunitas yang erat tetapi masih patriarki dan misoginis. Dalam segi agama, masyarakat Kairo menganggap kehendak Tuhan yang mahakuasa sebagai penyebab segala sesuatu dalam hidup. Dalam segi ekonomi, masyarakat Kairo sulit mendapatkan banyak kesempatan ekonomi karena adanya kelas sosial.
This study aims to describe (1) the structure of the novel Khan Al-Khalili by Naguib Mahfouz and (2) the perspective of the author contained in the novel "Khan Al-Khalili" by Naguib Mahfouz through the theory of Perspective.
The approach used in this research is the genetic structuralism approach. The object of this research is the novel "Khan Al-Khalili" by Naguib Mahfouz. This novel was translated into English by Roger Allen and published by Anchor Books in 2008. The instrument in this research is the human instrument. Data were obtained by reading and note-taking techniques. The data were analyzed by dialectical method.
The results of the study show (1) there are several structures that build the novel "Khan Al-Khalili" by Naguib Mahfouz, including this novel with the theme of romance and set in Cairo, Egypt. While the time setting lasts for one year, starting from 1941-to 1942. The social background can be seen in attitudes, social status, beliefs, and social organization. While the characters in this novel consist of Ahmad Akif, Rushdi Akif, and Nawal, who are the main characters. Meanwhile, additional characters are Akif Ahmad Effendi, Sitt Dawlat, Kamal Khalil, Sitt Tauhida, Boss Nunu, and Ahmad Rashid. This novel uses a mixed plot because there are several flashback scenes in the story. In addition, the point of perspective used in this novel is a third-person omniscient point of perspective. Then, the message contained in this novel is that we must be grateful for the life we live and also have to take better care of ourselves in our actions so that there will be no regrets in the future.
(2) The perspective of the author Naguib Mahfouz in his novel "Khan Al-Khalili" is the author wants to reveal to the reader the influence of War II on the Cairo people in terms of politics, social and cultural life, religion, and economy. In terms of politics, there is a conflict between conservative and liberal ideologies in Cairo society. In terms of social and cultural life, the Cairo community has a close community but is still patriarchal and misogynistic. In terms of religion, the people of Cairo regard the will of almighty God as the cause of everything in life. From an economic perspective, it is difficult for the people of Cairo to get many economic opportunities because of their social class
Dynamics of erythrocytes, vesicles and capsules in shear flow: the role of membrane bending stiffness and membrane viscosity
Three-dimensional numerical simulations using immersed boundary/front-tracking
method are considered to study the dynamics and deformation of microscopic deformable cells with elastic and viscoelastic membranes suspended in linear shear flow. The objective in this thesis is to understand the complex fluid/structure interaction problem for membrane-bound soft matter in dilute suspensions. The numerical model includes all essential properties of the cell membrane, namely, the resistance against shear deformation, area dilatation, and bending, as well as the viscosity difference between the cell interior and suspending fluids. In addition, the Kelvin–Voigt viscoelastic model is incorporated to account for the effect of membrane viscosity. Our numerical technique is able to simulate complex dynamics of vesicles, capsules, and red blood cells in the tank-treading, breathing, trembling, and tumbling modes. A detailed comparison of the numerical results for vesicles is made with various theoretical models and experiments. It is found that the applicability of the theoretical models is limited to quasi-spherical vesicles. We show that near the transition between the tank-treading and tumbling dynamics, both the vacillating-breathing-like motion characterized by a smooth ellipsoidal shape, and the trembling-like motion characterized by a highly deformed shape are possible. We also present phase diagrams of the single red blood cell dynamics in linear shear flow. We find that the cell dynamics is often more complex than the well-known tank-treading, tumbling, and swinging motion and is characterized by an extreme variation of the cell shape. Identifying such complex shape dynamics termed here as breathing dynamics, is the focus of this study. Further, we find a very good agreement between our numerical and the theoretical and experimental results on the tank-treading frequency of red blood cells, which is often measured in experiments and used to extract the mechanical properties of the cell. A comprehensive analysis of the influence of the membrane viscosity on buckling, deformation and dynamics is given for initially spherical or oblate capsules. The major finding here is that the membrane viscosity leads to buckling in the range of shear rates in which no buckling is observed for capsules with purely elastic membrane.Ph. D.Includes bibliographical referencesIncludes vitaby Alireza Zarif Khalili Yazdan
The Glorious World of Yabu Meizan : Comparing the Heisei Memorial Art Gallery and Khalili Collections
Session II : Modernizing Craft and FashionThe life of potter Yabu Meizan (1853-1934) closely followed the historical course of Japan’s modern export ceramic industry. He was a craftsman and entrepreneur representing the modernity of his day who made and sold Satsuma ware pottery in Osaka. As the recipient of numerous awards at western world expositions, Yabu Meizan’s works were highly appraised, and attracted numerous new customers. As a result, many of his creations are today proudly displayed in Western museums as representative of Japanese ceramic works produced following the advent of Japan’s Modern Age. I will cover the reasons for this success while describing many of the features of Meizan’s works, and what relationship these characteristics have with the Japaneseness inherent in his creations. One facet of Yabu Meizan’s high assessment is the quality of the illustrations painted by his workshop on small porcelain pieces. One of the first books to feature these elaborate paintings, and one of the first to introduce Yabu Meizan’s works to the world, was The Nasser D. Khalili Collection: Japanese Art That Crossed the Sea, published by Dōhōsha in 1995 as Vol. 5, Ceramic Art, based on the Nasser D. Khalili (1945-) Collection, which introduced 103 pieces of Meizan’s works. Last year, the author released the book, The Glorious World of Yabu Meizan, which features 147 pieces from the Heisei Memorial Art Collection. I will be comparing individual pieces from the two collections, highlighting 103 pieces from the Khalili Collection and 147 pieces from the Heisei Collection, in order to provide a detailed analysis of the transition of these pieces, their motifs, and how Meizan’s works were exhibited at the 1910 Japan-British Exhibition, as well as their appraisal in other countries
The Glorious World of Yabu Meizan : Comparing the Heisei Memorial Art Gallery and Khalili Collections
Session II : Modernizing Craft and FashionThe life of potter Yabu Meizan (1853-1934) closely followed the historical course of Japan’s modern export ceramic industry. He was a craftsman and entrepreneur representing the modernity of his day who made and sold Satsuma ware pottery in Osaka. As the recipient of numerous awards at western world expositions, Yabu Meizan’s works were highly appraised, and attracted numerous new customers. As a result, many of his creations are today proudly displayed in Western museums as representative of Japanese ceramic works produced following the advent of Japan’s Modern Age. I will cover the reasons for this success while describing many of the features of Meizan’s works, and what relationship these characteristics have with the Japaneseness inherent in his creations. One facet of Yabu Meizan’s high assessment is the quality of the illustrations painted by his workshop on small porcelain pieces. One of the first books to feature these elaborate paintings, and one of the first to introduce Yabu Meizan’s works to the world, was The Nasser D. Khalili Collection: Japanese Art That Crossed the Sea, published by Dōhōsha in 1995 as Vol. 5, Ceramic Art, based on the Nasser D. Khalili (1945-) Collection, which introduced 103 pieces of Meizan’s works. Last year, the author released the book, The Glorious World of Yabu Meizan, which features 147 pieces from the Heisei Memorial Art Collection. I will be comparing individual pieces from the two collections, highlighting 103 pieces from the Khalili Collection and 147 pieces from the Heisei Collection, in order to provide a detailed analysis of the transition of these pieces, their motifs, and how Meizan’s works were exhibited at the 1910 Japan-British Exhibition, as well as their appraisal in other countries
SlideWiki – A Platform for Authoring FAIR Educational Content
SlideWiki.org is a Web-based OpenCourseWare (OCW) authoring system that enables educators and learners to collaborate on creating, sharing, re-using and re-purposing multi-lingual open educational content. The SlideWiki platform allows people to author FAIR(Findable, Accessible, Interoperable, and Reusable) educational content.SlideWiki supports many features to semantically-enrich educational con-tent to support FAIR authoring. In this paper we will present those features of the platform such as Linked Data interface, manual and automatic content annotation as well as content linking and metadataSee CEUR version on http://ceur-ws.org/Vol-2198/paper_108.pd
An investigation of factors influencing the acceptance of open access publishing among medical researchers in Iran / Leila Khalili
Open access publishing provides unlimited free access to peer-reviewed articles published in open access journals. It is a way of sharing scientific knowledge and provides equal access to researchers from all over the world, especially for those unable to afford paid subscriptions. The success of this scholarly communication media depends a great deal on its acceptance by researchers. Several studies have previously investigated open access from the perspective of researchers in developed countries. However, because of diverse cultural, educational, economic and technological factors in the world, there is no ―one-size-fits-all‖ solution. It is well known that developing countries lag behind in open access practices. As a developing country, Iran has not been the subject of much research and the opinions of Iranian researchers regarding open access have not been investigated well. The aim of this study was to determine the current status of open access among Iranian medical researchers, and the factors influencing acceptance of open access publishing among them. This study used a survey design and a questionnaire as data collection instrument. The theoretical framework for the study was based on dimensions of the UTAUT model. The sample comprised 367 clinical/basic science academic staff of medical schools at public medical universities in Iran, selected using proportionate stratified sampling. The findings of study indicate that there is low familiarity with terms, initiatives and services of open access. Researchers use six open access services (open access journals, Iranian open access journals, DOAJ, BMC, PLoS and PubMed Central) more as readers than as authors. About half (47.7%) of the researchers had not submitted any manuscripts to open access journals. The researchers had low self-archiving experience (pre-print 4.4%, post-print 16.7%), but a majority of them (71%) were keen to archive if their universities were to set up an institutional repository. Based on mean scores, seven factors -- facilitating conditions, effort expectancy, performance expectancy, attitudes, concerns with author-pay, social influence, and anxiety -- influenced acceptance of open access publishing. Results of hierarchical multiple regression indicate that out of the 14 predictors of intention to use open access journals, only experience, attitude, facilitating conditions and type of university were significant. Also, results of regression show that out of 14 predictors of the use of open access journals, only intention, social influence, attitude, academic ranking, facilitating conditions, type of university and familiarity were significant key predictors. The results also suggest that researchers in top universities used open access journals more than researchers in lower ranked universities, but those from lower ranked universities had greater intentions to use these journals in future. The influence of concerns with author-pays on intention to use open access journals among researchers in Type One universities was higher than researchers in Type Two and Three universities. Also the influence of concerns with author-pays on use of open access journals among female researchers was higher than male ones. Eight constructs and six demographic factors together explain 22.3% of the variance in the use of open access journals. Seven constructs and seven demographic factors together explain 24.1% of the variance in intention to use open access journals. This study is significant in that, it provided a description of the current status of open access among Iranian medical researchers. It also investigated the acceptance of open access among researchers based on a theoretical framework derived from the UTAUT model, as well as inclusion of attitudes and anxiety as dimensions influencing acceptance
Neutralization of Lethal Potency of Tetanus Toxin using Phage Display Produced scFv Antibody
Background and Aim: Phage display technology provides a new approach for making human antibody fragments that could be applicable in passive immune therapy. We applied the use of this technology to make human single-chain variable fragments (scFvs) specific for tetanus toxin. Tetanus toxin is a neurotoxin constituted by the association of two subunits, mediates its lethal action by blocking neuromuscular vesicle docking.
Methods: We previously found that six Human scFv clones inhibit toxin binding to ganglioside GT1b. This is the final report of human tetanus scFvs (scFv 8 and scFv 13) isolated from an immunized library of more than 106 scFv clones with in vivo neutralizing activity.
Results: Only scFv 13 can reduce the in vivo toxicity induced by tetanus toxin. Also, scFv 8 has a weak capability of reducing the in vivo toxicity of the toxin.
Conclusion: These selected ScFvs can be considered as a possible option to substitute the human tetanus immunoglobulin (HTIG) which is extensively current immunotherapy for tetanus patients. Taken together, our results suggest that the use of human tetanus scFvs may lead to a less aggressive passive immune therapy against tetanus.
*Corresponding Author: Mahdi Aminian; Email: [email protected]
Please cite this article as: Khalili E, Abbasi E, Aminian M. Neutralization of Lethal Potency of Tetanus Toxin using Phage Display Produced ScFv Antibody.Arch Med Lab Sci. 2021;7:(e3). https://doi.org/10.22037/amls.v7.3378
Building temporary structures with sand in the hot-arid climate of Saudi-Arabia
For a travelling exhibition in Saudi-Arabia I have researched ways to build with sand in a temporary way. Using the existing sandbag-technique 'super adobe' of Nader Khalili combined with an inflatable roof a new method is born. This building system allows changes and flexibility when the building travels. It is more sustainable than the current systems and can adapt easy. The design-focus is on traditional Arabian building methods and geometric patterns. The fundaments of beauty and proportion are researched.Architectural Engineering and TechnologyArchitecture and The Built Environmen
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