247,023 research outputs found

    Manuscript slave deed, dated February 2, 1830, Rockbridge County, Virginia, from Larkin Powers to Thomas Johnston.

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    Know all men by these presents that I Larkin Powers of the County of Rockbridge and the State of Virginia have .?. by these presents do sell unto Thomas Johnston of the county and state aforesaid a negro woman named Hannah for the consideration of one sorrel horse of the value of fifty dollars and in cash fifteen dollars the act of which I ackowledge and I do warrant and defend the health and title of said negro against the claims or clauses of all persons in writing whereof I have herewith Let my hand and seal this 2nd day of February 1830 Larkin Powers (seal) Test ? B. Surretthttps://digitalcommons.usm.maine.edu/slavery/1003/thumbnail.jp

    Arginine depletion as a mechanism for the immune privilege of corneal allografts.

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    The cornea is an immune privileged tissue. Since arginase has been found to modulate T-cell function by depleting arginine, we investigated the expression of arginase in the cornea and its possible role in immune privilege using a murine transplant model. We found that both the endothelium and epithelium of murine corneas express functional arginase I, capable of down-regulating T-cell proliferation in an in vitro culture system. The administration of the specific arginase inhibitor N-hydroxy-nor-L-Arg to recipient mice resulted in an accelerated rejection of allogeneic C57BL/6 (B6) corneal grafts. In contrast, in vivo blockade of arginase activity had no effect in altering the course of rejection of primary skin grafts that express little, if any, arginase. In addition, the inhibition of arginase did not alter systemic T-cell proliferation. These data show that arginase is functional in the cornea and contributes to the immune privilege of the eye, and that modulation of arginase contributes to graft survival

    PHILIP LARKIN: INNOVAZIONI DI UN ANTI-MODERNO

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    In un recente sondaggio condotto dal Times su cinquanta scrittori britannici più amati dal dopoguerra a oggi, Philip Larkin è risultato il primo in classifica. Nonostante la sua produzione poetica si basi soltanto su quattro raccolte di versi pubblicate nell’arco di un trentennio a dieci anni di distanza l’una dall’altra, – The North Ship (1945), The Less Deceived (1955), The Whitsun Weddings (1964) e High Windows (1974), a cui si aggiungono pochi altri componimenti, Larkin gode di fama indiscussa. Lo testimoniano le riedizioni dei Collected Poems (1988) curati da Anthony Thwaite, le numerose monografie e i contributi critici che vanno ad arricchire la già copiosa bibliografia critica sul poeta. Notevole è anche il lavoro di approfondimento e divulgazione condotto dalla Philip Larkin Society, nata nel 1995 in occasione del decimo anniversario della morte dell’autore, che promuove e incoraggia gli studi larkiniani sia in territorio britannico che nel resto del mondo, grazie a programmi annuali fittissimi di eventi, conferenze, giornate di studio, incontri e alla preziosa rivista dell’associazione “About Larkin”. Ciononostante, Larkin è ancora semisconosciuto in Italia, almeno al grande pubblico. A parte alcune traduzioni, la prima datata 1969, Le nozze di Pentecoste e altre poesie per Einaudi e, più recente, Finestre Alte (2002), sempre per Einaudi, nella nostra lingua è disponibile solo l’edizione del romanzo Turbamenti a Willow Gables (2003). Si parte dal contesto culturale all’interno del quale l’autore inizia a muovere i primi passi, quello del Movement inglese, fenomeno letterario degli anni ‘50 del 1900, in cui Larkin si inserisce, interagendo e collaborando con altre figure altrettanto importanti come Donald Davie, John Wain, Thom Gunn, D.J. Enright ed Elizabeth Jennings; poi vengono descritti dettagliatamente i differenti punti di vista di Larkin e Kingsley Amis, fino ad analizzare l’influenza che Auden ha avuto su Larkin. Infine, ulteriore intento di questo elaborato, è quello di affrontare l’analisi dettagliata di alcuni testi poetici, tra i più significativi, contenuti nelle varie raccolte poetiche, per mostrare le differenti tematiche affrontate dall’autore. Il Movement, il fenomeno letterario più importante nell’Inghilterra del secondo dopoguerra, nasce tra il ‘53 e il ‘55, grazie ad alcuni poeti formatisi presso le università di Oxford a Cambridge. A Oxford nel 1940 si incontrano Philip Larkin e Kingsley Amis, i due rappresentanti più importanti del movimento, entrambi affascinati dal lavoro di Gavin Bone, uno studioso di poesia anglosassone. Entrambi pubblicano le loro prime opere con la Fortune Press. Successivamente sulla scena letteraria inglese compare John Wain, un altro futuro membro del Movement, che è attratto proprio dalla sobrietà, dallo stile sintetico e dalla Englishness dei due giovani scrittori. Sempre negli anni Quaranta, a Cambridge, D.J. Enright, Donald Davie e Thom Gunn fanno propri i valori di chiarezza, dedizione e disciplina, apprezzando i modelli letterari augustei che potessero fungere da esempi nella trattazione delle vicende quotidiane. A definire chiaramente il Movement compaiono poi due antologie, Poets of the Fifties, uscita nel 1955 a cura di D.J. Enright e New Lines di Robert Conquest. Nelle due raccolte compaiono gli stessi otto poeti: Enright, Wain, Conquest, Larkin, Davie, Holloway, Amis, Jennings, mentre Gunn è rappresentato soltanto in New Lines. La figura di maggior spicco nel Movement è quella di Philip Larkin (1922-1985), il quale è stato definito, secondo recenti studi, misogino, sprezzante nei confronti della classe operaia, sciovinista, onanista, pornografo e forse ammiratore (sulla scia del padre) della Germania hitleriana. L’ambientazione tipica delle sue poesie è la provincia industriale, con pub, alberghi georgiani, camere in affitto, corsie d’ospedale, fiere e chiese di periferia. I suoi antieroi sono soggetti egoisti ossessionati dalla propria morte, burocrati vittime della routine lavorativa, inetti in amore, uomini sulla mezza età che invidiano l’energia dei giovani, denigratori della vita e nostalgici di quella potenza imperiale oramai andata. Nonostante ciò, non riescono ad allontanarsi dal mondo a cui appartengono per affrontare l’ignoto, infatti Larkin stesso non voleva allontanarsi dalla sua Inghilterra, poiché sosteneva che prima o poi sarebbe dovuto tornare. In a recent Times survey of the 50 most beloved British writers since the post-war period, Philip Larkin was the first. Although his poetic output is based on only four collections of verses published over a period of 30 years – The North Ship (1945), The Less Deceived (1955), The Whitsun Weddings (1964) and High Windows (1974), to which he has added few other compositions, Larkin enjoys undisputed fame. To confirm this, there are the re-editions of Anthony Thwaite’s Collected Poems (1988), as well as the numerous monographs and critical contributions that enrich the already copious critical bibliography on the poet. The Philip Larkin Society, founded in 1995 on the occasion of the tenth anniversary of the author’s death, is also noteworthy. It promotes and encourages Larkin’s studies both in the UK and throughout the world, thanks to its extensive annual programmes of research and development. Larkin is still semi-unknown in Italy, at least to the general public. Apart from a few translations, the first one dated 1969, 'Le nozze di Pentecoste' and other poems for Einaudi and, more recently, 'Finestre Alte' (2002), also for Einaudi, only the edition of 'Turbamenti a Willow Gables' (2003) is available in our language. It starts from the cultural context within which the author begins to take his first steps, that of the English Movement, a literary phenomenon of the 1950s of 1900, in which Larkin enters, interacting and collaborating with other equally important figures such as Donald Davie, John Wain, Thom Gunn, D. J. Enright and Elizabeth Jennings; Larkin’s and Kingsley Amis’s different points of view are described in detail, and the influence Auden had on Larkin is analysed. Finally, a further aim of this work is to address the detailed analysis of some of the most significant poetic texts contained in the various collections of poetry, in order to show the differences The Movement, the most important literary phenomenon in post-World War II in England, was founded between '53 and '55 thanks to poets trained at the universities of Oxford in Cambridge. At Oxford in 1940 they met Philip Larkin and Kingsley Amis, the two most important representatives of the Movement, both fascinated by the work of Gavin Bone, a scholar of Anglo-Saxon poetry. Both publish their first works with Fortune Press. Later, John Wain, another future member of the Movement, appeared on the English literary scene, who was attracted by the sobriety, synthetic style and Englishness of the two young writers. Also in the 1940s, in Cambridge, D. J. Enright, Donald Davie and Thom Gunn adopted the values of clarity, dedication and discipline, appreciating the Augustan literary models that could serve as examples in dealing with everyday events. Two anthologies, Poets of the Fifties, published in 1955 by D. J. Enright and New Lines by Robert Conquest, clearly define the Movement. The same eight poets appear in the two collections: Enright, Wain, Conquest, Larkin, Davie, Holloway, Amis, Jennings, while Gunn is only represented on New Lines. The most prominent figure in the Movement is that of Philip Larkin (1922-1985), who has been described, according to recent studies, as a misogynist, scornful of the working class, chauvinist, onanist, pornographer and perhaps an admirer (in his father’s footsteps) of Hitler’s Germany. The typical setting of his poems is the industrial province, with pubs, Georgian hotels, rooms for rent, hospital wards, fairs and suburban churches. Its anti-heroes are selfish subjects obsessed with their own death, bureaucrats victims of the work routine, inept in love, middle-aged men who envy the energy of young people, denigrators of life and nostalgic for that power.Despite this, they are unable to move away from the world they belong to to to face the unknown, in fact Larkin himself did not want to move away from his England, because he argued that sooner or later he would have to return

    Spiritual Visions in Philip Larkin

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    In this thesis I intend to examine how Larkin expresses his attitude towards religion and/or transcendentalism by introducing these “spiritual visions” in his poems. In the first chapters I aim to focus on those literary traditions which had major impact on the poet and introduce the ever struggling/opposing sides of Larkin as being a romantic writer or a follower of the realistic traditions. I also intend to investigate the relationship between Larkin, religion and transcendentalism and analyse his related poems in the field; my aim is to focus on a previously chosen poem in a given ‘category’. The poems will be the following ones: ‘Church Going’ in his expression of need to believe; ‘The Building’ related to his thoughts on death; ‘The Explosion’ to offer immortality; ‘An Arundel Tomb’ that questions the existence of surviving love; ‘The Trees’ which sets the image of re-birth in front of us; ‘High Windows’ on rejection of God and finally ‘Water’ that aims to construct some kind of religion if we are left without faith.angol nyelv és irodalom szakos tanár (távoktatás)egyetem

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Towards hardware acceleration of neuroevolution for multimedia processing applications on mobile devices

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    This paper addresses the problem of accelerating large artificial neural networks (ANN), whose topology and weights can evolve via the use of a genetic algorithm. The proposed digital hardware architecture is capable of processing any evolved network topology, whilst at the same time providing a good trade off between throughput, area and power consumption. The latter is vital for a longer battery life on mobile devices. The architecture uses multiple parallel arithmetic units in each processing element (PE). Memory partitioning and data caching are used to minimise the effects of PE pipeline stalling. A first order minimax polynomial approximation scheme, tuned via a genetic algorithm, is used for the activation function generator. Efficient arithmetic circuitry, which leverages modified Booth recoding, column compressors and carry save adders, is adopted throughout the design

    Les biblioteques universitàries i el suport a la recerca

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    The European Higher Education Area and the European Research Area are currently two key objectives for university learning, teaching and research in all European universities. University libraries must meet the challenges by offering the best library services to the academic community. In drafting the second strategic plan, Rebiun (Network of University Libraries) gathered comments and suggestions from professionals in Spanish university libraries. This article presents the reflections and suggestions contributed by the author regarding the support services that university libraries could offer for university research.L'espai europeu d'educació superior i l'espai europeu d'investigació són actualment dos objectius clau per a l'aprenentatge, la docència i la recerca de totes les universitats europees. Les biblioteques universitàries han de contribuir a aquests reptes, oferint els millors serveis bibliotecaris a la comunitat acadèmica. En la fase d'elaboració del seu segon Pla estratègic, la REBIUN (Red de Bibliotecas Universtarias) va recollir reflexions i suggeriments de diferents professionals de les biblioteques universitàries de l'Estat espanyol. En l¿article següent es presenten les reflexions i els suggeriments aportats per l'autora sobre el suport que les biblioteques universitàries poden oferir a la recerca universitària
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