67,670 research outputs found
LANG (T.)
No full textDubois Patrick. LANG (T.). In: , . Le dictionnaire de pédagogie et d'instruction primaire de Ferdinand Buisson : répertoire biographique des auteurs. Paris : Institut national de recherche pédagogique, 2002. p. 92. (Bibliothèque de l'Histoire de l'Education, 17
LANG (T.)
No full textDubois Patrick. LANG (T.). In: Le dictionnaire de pédagogie et d'instruction primaire de Ferdinand Buisson : répertoire biographique des auteurs. Paris : Institut national de recherche pédagogique, 2002. p. 92. (Bibliothèque de l'Histoire de l'Education, 17
Generalized structured additive regression based on Bayesian P-splines
No full textGeneralized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Bayesian GAM's and extensions to generalized structured additive regression based on one or two dimensional P-splines as the main building block. The approach extends previous work by Lang und Brezger (2003) for Gaussian responses. Inference relies on Markov chain Monte Carlo (MCMC) simulation techniques, and is either based on iteratively weighted least squares (IWLS) proposals or on latent utility representations of (multi)categorical regression models. Our approach covers the most common univariate response distributions, e.g. the Binomial, Poisson or Gamma distribution, as well as multicategorical responses. For the first time, we present Bayesian semiparametric inference for the widely used multinomial logit models. As we will demonstrate through two applications on the forest health status of trees and a space-time analysis of health insurance data, the approach allows realistic modelling of complex problems. We consider the enormous flexibility and extendability of our approach as a main advantage of Bayesian inference based on MCMC techniques compared to more traditional approaches. Software for the methodology presented in the paper is provided within the public domain package BayesX
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Implants used for orthodontic anchorage
No full textThe fifth edition of Clinical Periodontology and Implant Dentistry brings to its readers another iteration of the unrivalled, unparalleled work on the specialty of periodontics. The editors have brought together contributions from experts all over the world to provide the reader with a comprehensive, cohesive text that fuses scholarship and science with clinical instruction and pragmatism. Clinical Periodontology runs the gamut of sub-disciplines and topics within periodontics and implant dentistry, supporting an intellectually and internationally inclusive approach.
The fifth edition includes a wealth of new and revised chapters that reflect developments in the field in the years since the fourth edition was published. The sections on anatomy of the periodontium and the basic sciences underlying tooth and implant attachment have been expanded, as has the section on pathology and pathogenesis of periodontitis. Increased interest in the interdisciplinary aspects of periodontology is reflected by new chapters on orthodontic anchorage. Other important topics with increased prominence include: risk assessment and host-modulation therapies, regenerative therapies, and a full discussion of surgical and non-surgical therapies.
With an approximate increase in length of 25% and over 15 new chapters, the 5th edition of Clinical Periodontology and Implant Dentistry has grown beyond the confines of one volume. Two volumes divide the topics into basic sciences and applied clinical concepts, at the same time maintaining a seamless integration between the two.
This book is the cornerstone of periodontology, and represents a unique distillation of the specialty by an expert group of authors under the tutelage of a legendary editorial team
THE DYNAMICAL MORDELL-LANG CONJECTURE for ENDOMORPHISMS of SEMIABELIAN VARIETIES DEFINED over FIELDS of POSITIVE CHARACTERISTIC
No full textLet K be an algebraically closed field of prime characteristic p, let X be a semiabelian variety defined over a finite subfield of K, let Phi : X -> X be a regular self-map defined over K, let V subset of X be a subvariety defined over K, and let alpha is an element of X(K). The dynamical Mordell-Lang conjecture in characteristic p predicts that the set S = {n is an element of N: Phi(n)(alpha) is an element of V} is a union of finitely many arithmetic progressions, along with finitely many p-sets, which are sets of the form {Sigma(m)(i=1) c(i) p(ki ni) : n(i) is an element of N} for some m is an element of N, some rational numbers ci and some non-negative integers ki. We prove that this conjecture is equivalent with some difficult diophantine problem in characteristic 0. In the case X is an algebraic torus, we can prove the conjecture in two cases: either when dim(V) <= 2, or when no iterate of 8 is a group endomorphism which induces the action of a power of the Frobenius on a positive..
Perrault's popular tales,ed. from the original editions, with introduction, &c. By Andrew Lang ...
No full textFrom the original editions, with introduction, &c. By Andrew Lang ...Tales preceded by reproduction of t.-p. of the Paris edition of 1697: Histoires ou contes du temps passé. Avec des moralitéz
Le chemin de fer de Phu Lang Thuong à Lang Son
No full textLe chemin de fer de Phu Lang Thuong à Lang Son. In: Annales de Géographie, t. 2, n°8, 1893. p. 450
Le chemin de fer de Phu Lang Thuong à Lang Son
No full textLe chemin de fer de Phu Lang Thuong à Lang Son. In: Annales de Géographie, t. 2, n°8, 1893. p. 450
Dietrich Blaufuss, Spener-Arbeiten, Quellenstudium und Untersuchungen zu Philipp Jakob Spener und zur frühen Wirkung des lutherischen Pietismus. Publications univ.-europ. Série XXIII, t. 46 — H. Lang, Berne -P. Lang, Francfort, 1975
No full textLienhard Marc. Dietrich Blaufuss, Spener-Arbeiten, Quellenstudium und Untersuchungen zu Philipp Jakob Spener und zur frühen Wirkung des lutherischen Pietismus. Publications univ.-europ. Série XXIII, t. 46 — H. Lang, Berne -P. Lang, Francfort, 1975. In: Revue d'histoire et de philosophie religieuses, 58e année n°2,1978. p. 1
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