1,721,575 research outputs found

    Genetics and sudden death

    No full text
    PURPOSE OF REVIEW: Sudden cardiac death (SCD) affects a significant percentage of young individuals. SCDs are due to genetic heart disorders, such as cardiomyopathies and channelopathies. In the present review, we will describe the recent advancements in understanding the genetic and molecular basis of hereditary cardiac diseases. RECENT FINDINGS: Considerable progress has been made in identification of new genes associated with monogenic familial arrhythmogenic syndromes, giving the opportunity to delineate their molecular pathogenesis and identify potential targets for therapeutic intervention. Research discoveries and rapidly dropping costs of DNA sequencing technologies have resulted in availability of genetic testing panels. SUMMARY: Advances in genetic sequencing technology are expected to significantly impact the clinical practice in the near future. Genetic testing represents a powerful tool for cause determination of arrhythmogenic cardiac diseases, efficient screening of family members, possible risk stratification and treatment choices. However, specific expertise is required for rational ordering and correct interpretation of the genetic screening results. © 2013 Wolters Kluwer Health | Lippincott Williams &Wilkins

    The digital transformation of corporate reporting – a systematic literature review and avenues for future research

    No full text
    Purpose: This paper aims to provide a systematic literature review (SLR) of the relationship between smart and digital technologies and organisations’ reporting processes, proposing a future research agenda. The paper examines the effects of data and digital technology on the corporate reporting process by analysing the various kinds of reports by organisations. Design/methodology/approach: A two-decade assessment of studies was analysed to answer research questions. A SLR explored the role of digital and smart technologies for corporate reporting processes. The Scopus database was used as a leading source for access to the articles. Initially, 163 items were collected. After reading the abstract and several refinements, 43 prioritised publications were analysed and categorised to derive significant results. Findings: Results of the analysis highlight the following emerging research streams about the digital transformation of corporate reporting: digital technology for corporate information management and decision-making processes; digital technologies as a tool of stakeholder engagement and sustainable reporting practices; and finally, digital technologies as a way to address earning management, corporate social responsibility, accountability and transparency. Research limitations/implications: How digital technology and data analytics may potentially transform the corporate reporting process to make it more effective, resulting in greater transparency for shareholders and all stakeholders. Originality/value: The originality of this paper derives from connecting, for the first time, smart and digital technologies and corporate reporting processes, drafting the state of the art of this research topic for future research

    Dimensione territoriale, piccole e medie imprese e mercato del credito: un'ipotesi per la Basilicata

    No full text
    Quaderno del Dipartimento di Scienze Economiche e Statistiche dell'Università di Salern

    Socio-economic value co-creation and sports tourism: evidence from Tasmania

    No full text
    Tasmania, the island state of Australia has been steadily escalating its appeal as a tourist destination. The state government’s ‘sports-tourism’ partnership with the Hawthorn Football Club plays a key role to promote the tourism industry, and to contribute to various socio-economic issues of Tasmania. This case study attempts to analyse the relationships and interactions of these two partners, as they both work interdependently towards their multifarious goals. The findings descriptively portray the influence of relationship marketing (RM) on the mutually beneficial relationship value of Tasmania and Hawthorn, where RM steers their initial mutual value alongside their interdependence and multifarious socio-economic goals, towards a win-win outcome and further socio-economic value co-creation for all associated stakeholders. The findings contribute to the contemporary understanding of interrelations and interdependence among the stakeholders from sports-tourism, destination marketing and socio-economic development perspectives and suggest its research and practical significance

    Aetiology and pathogenesis of hypertrophic cardiomyopathy

    No full text
    Supplemen

    Le direttrici di ricerca per il futuro delle smart technologies, del processo di digitalizzazione aziendale e del capitale intellettuale

    No full text
    Lo studio delle smart technologies (Lombardi, 2019; Marchi et al. 2015), dei processi di digitalizzazione aziendale (Allen, 2019; Fera et al., 2020; Moscariello, Pizzo, 2020; Routley et al., 2013; Sathananthan et al., 2018; Timmers, 1998) e del capitale intellettuale (Bontis, 1998; Edvins-son, Malone, 1997; Lombardi, Dumay, 2017; Marchi, Marasca, 2010; San-chez, Chaminade, Olea, 2000; Roos, G., Bainbridge, Jacobsen, 2011) ha assunto sempre più rilievo negli ultimi anni, soprattutto alla luce delle for-ti implicazioni sulle organizzazioni contemporanee (ad esempio, aziende profit e no profit), gruppi e individui. Sebbene tale contesto di ricerca non abbia ancora raggiunto la sua maturità e sia in forte ascesa, molteplici di-rettrici di ricerca possono essere tracciate nell’ambito dell’economia aziendale. In questa prospettiva, appare rilevante tracciare lo stato dell’arte degli studi economico-aziendali relativi alle smart technologies, alla digitalizza-zione aziendale e al capitale intellettuale per comprenderne pienamente il potenziale di sviluppo nello scenario internazionale. Pertanto, il presente contributo si pone l’obiettivo di proporre una revi-ew della letteratura (“structured literature review”) (Kraus et al., 2020; Massaro et al., 2016; Petticrew, Roberts, 2006; Tranfield et al., 2003) sem-plificata sulle tre direttrici di ricerca che contraddistinguono tutto il volu-me Franco Angeli “Smart Technologies, Digitalization & Intellectual Ca-pital”. Attraverso l’uso del database Scopus (www.scopus.com), è stato possibile sviluppare l’analisi bibliometrica del presente contributo di ricer-ca, utilizzando le principali parole chiave per creare un collegamento tra 1) smart technologies, 2) digitalizzazione, 3) capitale intellettuale e la tradi-zione di studi economico-aziendali che nello scenario internazionale si in-quadrano principalmente nell’accounting research. Da qui, una lista di studi pubblicati nei journal scientifici, ovvero in volumi di ricerca, procee-dings e così via è stata realizzata, determinando un’analisi di tipo “grey”

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
    corecore