1,976,921 research outputs found
A comment on "Intergenerational equity: sup, inf, lim sup, and lim inf"
Full text linkWe reexamine the analysis of Chambers (Social Choice and Welfare, 2009), that produces a characterization of a family of social welfare functions in the context of intergenerational equity: namely, those that coincide with either the sup, inf, lim sup, or lim inf rule. Reinforcement, ordinal covariance, and monotonicity jointly identify such class of rules. We show that the addition of a suitable axiom to this three properties permits to characterize each particular rule. A discussion of the respective distinctive properties is provided.Social welfare function; Intergenerational equity; Lim sup ; Lim inf
Multiple functions of LIM domain-binding CLIM/NLI/Ldb cofactors during zebrafish development
No full textThe crucial involvement of CLIM/NLI/Ldb cofactors for the exertion of the biological activity of LIM homeodomain transcription factors (LIM-HD) has been demonstrated. In this paper we show that CLIM cofactors are widely expressed during zebrafish development with high protein levels in specific neuronal cell types where LIM-HD proteins of the Isl class are synthesized. The overexpression of a dominant-negative CLIM molecule (DN-CLIM) that contains the LIM interaction domain (LID) during early developmental stages of zebrafish embryos results in an impairment of eye and midbrain-hindbrain boundary (MHB) development and disturbances in the formation of the anterior midline. On a cellular level we show that the outgrowth of peripheral but not central axons from Rohon Beard (RB) and trigeminal sensory neurons is inhibited by DN-CLIM overexpression. We demonstrate a further critical role of CLIM cofactors for axonal outgrowth of motor neurons. Additionally, DN-CLIM overexpression causes an increase of Isl-protein expression levels in specific neuronal cell types, likely due to a protection of the DN-CLIM/LIM-HD complex from proteasomal degradation. Our results demonstrate multiple roles of the CLIM cofactor family for the development of entire organs, axonal outgrowth of specific neurons and protein expression levels
Replication Data for: "The Informational Theory of Legislative Committees: An Experimental Analysis", Marco Battaglini; Ernest K. Lai; Wooyoung Lim; Joseph Tao-yi Wang
No full textReplication Data for: "The Informational Theory of Legislative Committees: An Experimental Analysis", Marco Battaglini; Ernest K. Lai; Wooyoung Lim; Joseph Tao-yi Wan
Replication Data for: "The Informational Theory of Legislative Committees: An Experimental Analysis", Marco Battaglini; Ernest K. Lai; Wooyoung Lim; Joseph Tao-yi Wang
No full textReplication Data for: "The Informational Theory of Legislative Committees: An Experimental Analysis", Marco Battaglini; Ernest K. Lai; Wooyoung Lim; Joseph Tao-yi Wan
Four and a half LIM protein 1C (FHL1C)
Full text linkFour-and-a-half LIM domain protein 1 isoform A (FHL1A) is predominantly expressed in skeletal and cardiac muscle. Mutations in the FHL1 gene are causative for several types of hereditary myopathies including X-linked myopathy with postural muscle atrophy (XMPMA). We here studied myoblasts from XMPMA patients. We found that functional FHL1A protein is completely absent in patient myoblasts. In parallel, expression of FHL1C is either unaffected or increased. Furthermore, a decreased proliferation rate of XMPMA myoblasts compared to controls was observed but an increased number of XMPMA myoblasts was found in the G(0)/G(1) phase. Furthermore, low expression of K(v1.5), a voltage-gated potassium channel known to alter myoblast proliferation during the G(1) phase and to control repolarization of action potential, was detected. In order to substantiate a possible relation between K(v1.5) and FHL1C, a pull-down assay was performed. A physical and direct interaction of both proteins was observed in vitro. In addition, confocal microscopy revealed substantial colocalization of FHL1C and K(v1.5) within atrial cells, supporting a possible interaction between both proteins in vivo. Two-electrode voltage clamp experiments demonstrated that coexpression of K(v1.5) with FHL1C in Xenopus laevis oocytes markedly reduced K(+) currents when compared to oocytes expressing K(v1.5) only. We here present the first evidence on a biological relevance of FHL1C
Clip from Interview with Melanie Lim
No full textAn excerpt from a video interview with Melanie Lim, part of the Cambodian American Community of Oregon\u27s oral history project documenting the experiences of survivors of the Cambodian genocide of 1975-1979.Interview by Lauro Lim, 29 May 2009.https://pdxscholar.library.pdx.edu/caco_interviews/1004/thumbnail.jp
Data used for Lim et al. (2024)
No full text<p>Data used in Lim et al. (2024)</p>
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<p>Lim, H., Cho, C. S., & Son, M. (2024). The 2022 Goesan earthquake of the moment magnitude 3.8 along the buried fault in the central Korean Peninsula. Journal of Seismology. https://doi.org/10.1007/s10950-024-10201-y</p>
Entrevista a Sean Lim en la Reunión CUDI, otoño 2013
No full textEntrevista con Sean Lim durante la Reunión CUDI, otoño 2013.Entrevista con Sean Lim, Vicepresidente mundial de EC - Council.13_10_02_sean_lim.fl
ARTICLES, REPORTS AND SPEECHES, 1998-2008 - Lectures - Lim Lecture, 2007
No full textLecture from CJ Lim on September 11, 2007.http://deepblue.lib.umich.edu/bitstream/2027.42/118142/2/39015094711705.mp4http://deepblue.lib.umich.edu/bitstream/2027.42/118142/3/39015094711705.zi
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