1,720,973 research outputs found

    Recording of electromyogram activity in the monkey during skilled grasping

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    This chapter provides a brief presentation of the available techniques for electromyogram (EMG) recordings in the awake monkey using chronically implanted electrodes. We illustrate how this technique can be used for the analysis of the monkey's motor behavior during dexterous grasp. We also investigate how the grasp specificity of EMG activity can be related to the activity of a population of pyramidal tract neurons (PTNs) recorded from the hand area of the primary motor cortex (M1).: Introduction: The ability to grasp and manipulate objects of various sizes and shapes is essential for a large range of human activities. The debilitating loss of skilled hand movements following stroke, spinal injury and many other pathological disorders results in a marked loss of autonomy for the affected patient. The characteristic structure of the human hand provides this organ with a unique combination of motor and sensory capacities that underpin the control of manual dexterity. The anatomy of the hand includes some 27 different bones, and some 39 different muscles located either in the forearm (extrinsic muscles) or in the hand itself (intrinsic muscles; Tubiana, 1981). Special features of bony structures in the hand contribute directly to dexterity, and are important for rotation of the human thumb during precision grip (Tallis, 2004). The muscular control of the multi-articulate hand presents some demanding biomechanical solutions

    Simultaneous recording of macaque premotor and primary motor cortex neuronal populations reveals different functional contributions to visuomotor grasp

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    Simultaneous recording of macaque premotor and primary motor cortex neuronal populations reveals different functional contributions to visuomotor grasp. J Neurophysiol 98: 488-501, 2007. First published February 28, 2007; doi: 10.1152/ jn.01094.2006. To understand the relative contributions of primary motor cortex ( M1) and area F5 of the ventral premotor cortex (PMv) to visually guided grasp, we made simultaneous multiple electrode recordings from the hand representations of these two areas in two adult macaque monkeys. The monkeys were trained to fixate, reach out and grasp one of six objects presented in a pseudorandom order. In M1 326 task- related neurons, 104 of which were identified as pyramidal tract neurons, and 138 F5 neurons were analyzed as separate populations. All three populations showed activity that distinguished the six objects grasped by the monkey. These three populations responded in a manner that generalized across different sets of objects. F5 neurons showed object/grasp related tuning earlier than M1 neurons in the visual presentation and premovement periods. Also F5 neurons generally showed a greater preference for particular objects/ grasps than did M1 neurons. F5 neurons remained tuned to a particular grasp throughout both the premovement and reach-to-grasp phases of the task, whereas M1 neurons showed different selectivity during the different phases. We also found that different types of grasp appear to be represented by different overall levels of activity within the F5-M1 circuit. Altogether these properties are consistent with the notion that F5 grasping-related neurons play a role in translating visual information about the physical properties of an object into the motor commands that are appropriate for grasping, and which are elaborated within M1 for delivery to the appropriate spinal machinery controlling hand and digit muscles

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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