44 research outputs found
"Essaouira. Rilettura della Medina"
No full textIl saggio presenta la città di Essaouira, quale caso emblematico di una situazione comune a molte città del Nord Africa, dove il rapido sviluppo urbano ha trasformato la Medina, la città murata, da nucleo urbano compiuto in quartiere marginale della città nuova. A Essaouira, come altrove, il centro storico è stato sfruttato come un elemento di economia esterna per l'intera città, poichè il patrimonio edilizio esistente poteva essere utilizzato, senza ingenti investimenti di capitale, per insediamenti produttivi e commerciali, da una parte, e come serbatoio residenziale per i ceti meno abbienti, dall'altra. Il rapido degrado fisico e socio-economico della Medina, però, almeno a Essaouira, non ne ha ancora completamente snaturato l'identità. E di questo aspetto si occupano gli autori, anche a parziale restituzione degli esiti di studi e rilievi sul campo svolti tra il 1995 e il 1998
Misting and fan cooling of the rest area in a dairy barn
No full textThis summer study aimed to evaluate the effect on dairy cows, kept in a free stall barn equipped with fans
and sprinklers in the feeding area, of the delivery rate of
misters in a cooling system in rest areas with different
bedding materials. Thirty cows were divided into two
homogenous groups according to milk yield and kept in
two pens: one had beds with sand (SAMM) while the other
had straw (STLM). Each pen was equipped with 2 fans (Ø
70 cm, 0.50 kW) and 2 misters (delivery rate of 11.2 and
22.5 L/h in STLM and SAMM, respectively) in the rest
area. Microclimatic parameters, rectal temperature (RT),
breathing rate (BR), milk yield, and some milk traits were
recorded. Behavioural routines of the cows (standing and
lying) were also continuously recorded during the hotter
days. During the trial, two mild–moderate heat waves were
observed. During these hotter periods, the daily maximum
temperature recorded in the rest areas was 28.9 in SAMM
and 31.2 in STLM, and the daily maximum THI was 78.2
in SAMM and 81.5 in STLM. In these periods, the cows in
SAMM compared with those in STLM showed lower BR
(P<0.05) and greater rest time (10.2 and 7.8 h/day in
SAMM and STLM, respectively). The RT did not differ
(38.89±0.29 and 38.88±0.33°C in STLM and SAMM r,
espectively). In conclusion, our research suggests that the
cooling system using fans plus misters with mild wetting in
rest areas with sand as bedding materials reduces heat stress
and improves cow comfort
Protective antifungal yeast killer toxin-like antibodies
No full textAfter several years of controversy, antibodies (Abs) are now believed to play an important role in the protection against fungal infections. Among them, recent data are strongly supporting the
relevance of protective yeast killer toxin-like Abs (“antibiobodies”, KT-Abs), which are able to exert a direct microbicidal activity by mimicking a killer toxin (PaKT) and its interaction with cell wall receptors on susceptible cells essentially constituted by beta-glucans. This review will focus on the implications of the yeast killer phenomenon, and, particularly, the occurrence and antimicrobial activity of protective antifungal KT-Abs, such as those produced during the course of experimental and natural infections caused by PaKT-sensitive microorganisms or produced by idiotypic vaccination with a PaKT-neutralizing mAb. The strong therapeutic activity exerted against different experimental mucosal and systemic mycoses by monoclonal and recombinant microbicidal KT-Abs (either in their soluble forms or expressed on human commensal bacteria) as well as by a synthetic killer peptide (KP, an antibody fragment engineered from the sequence of a recombinant KT-Ab) will be discussed. The surprisingly
wide antimicrobial spectrum of activity against eukaryotic and prokaryotic pathogenic agents, such as fungi, bacteria and protozoa, of these Abs and Ab-derived molecules suggests new potential strategies for transdisease anti-infective prevention and therapy
Inibizione della placca dentale prodotta da Streptococcus mutans mediante anticorpi monoclonali antibiotici in un modello ex vivo.
No full textInhibition by yeast killer toxin-like antibodies of oral streptococci adhesion to tooth surfaces in an ex vivo model
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In vitro activity of monoclonal and recombinant yeast killer toxin-like antibodies against antibiotic-resistant Gram-positive cocci.
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Antibodies killing Candida albicans, Pneumocystis carinii and Mycobacterium tuberculosis are fungicidal to Cryptococcus neoformans, C. glabrata and C. krusei.
No full textBiotechnological approaches to the production of idiotypic vaccines and antiidiotypic antibiotics
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