2,400 research outputs found
Silibinin attenuates antigen-specific IgE production through the modulation of Th1/Th2 balance in ovalbumin-sensitized BALB/c mice
No full textTissue engineering-based cartilage repair with allogenous chondrocytes and gelatin–chondroitin–hyaluronan tri-copolymer scaffold: A porcine model assessed at 18, 24, and 36 weeks
No full textCannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes.
No full textFH through the retrospectoscope
Full text linkAfter training as a gastroenterologist in the UK, the author became interested in lipidology while he was a research fellow in the USA and switched careers after returning home. Together with Nick Myant, he introduced the use of plasma exchange to treat familial hypercholesterolemia (FH) homozygotes and undertook non-steady state studies of LDL kinetics, which showed that the fractional catabolic rate of LDL remained constant irrespective of pool size. Subsequent steady-state turnover studies showed that FH homozygotes had an almost complete lack of receptor-mediated LDL catabolism, providing in vivo confirmation of the Nobel Prize-winning discovery by Goldstein and Brown that LDL receptor dysfunction was the cause of FH. Further investigation of metabolic defects in FH revealed that a significant proportion of LDL in homozygotes and heterozygotes was produced directly via a VLDL-independent pathway. Management of heterozygous FH has been greatly facilitated by statins and proprotein convertase subtilisin/kexin type 9 inhibitors but remains dependent upon lipoprotein apheresis in homozygotes. In a recent analysis of a large cohort treated with a combination of lipid-lowering measures, survival was markedly enhanced in homozygotes in the lowest quartile of on-treatment serum cholesterol. Emerging therapies could further improve the prognosis of homozygous FH; whereas in heterozygotes, the current need is better detection
Website accessibility : evaluating the WCAG conformance level of WordPress templates and the FH Joanneum GmbH's website
No full textDurch Content Management Systeme wie WordPress ist es auch Menschen ohne Ausbildung in Design oder Webentwicklung möglich, Webseiten schnell und günstig zu erstellen. Dies wird den BenutzerInnen dieser Systeme durch sogenannte Templates oder Vorlagen ermöglicht. Damit geht jedoch auch ein großes Problem bezüglich der Barrierefreiheit einher, da diese Templates nicht den gegebenen Standards unterliegen müssen. Zu Beginn dieser Arbeit wurden notwendige Begriffe wie Barrierefreiheit definiert. Ebenfalls wurden Behinderungen, welche die Benutzung von Webseiten negativ beeinflussen können, aufgezeigt und in vier Kategorien unterteilt. Daraufhin wurden drei Standards vorgestellt, mit deren Hilfe barrierefreie Webseiten, oder Templates, erstellt werden können. Diese Standards wurden von der Autorin aus dem Englischen ins Deutsche übersetzt und zusammengefasst. Anschließend wurden die vier meist genutzten, kostenlose WordPress Templates aus der Kategorie ‘Food & Drink’, sowie das einzige Template dieser Kategorie, welches als ‘Accessibility Ready’ gekennzeichnet wurde, auf ihre Barrierefreiheit untersucht. Diese Evaluierungen wurden manuell anhand der Demo-Versionen der Templates durchgeführt. Zusätzlich wird die Webseite der FH JOANNEUM GmbH, welche ebenfalls mit WordPress erstellt wurde, manuell untersucht. Ziel der Evaluierung war es herauszufinden welche Konformitätsstufe, nach den Web Content Accessibility Guidelines, diese Templates und die Webseite erreichen können. Die Evaluierung ergab, dass weder die untersuchten Templates, noch die Webseite der FH JOANNEUM GmbH auch nur die niedrigste Konformitätsstufe erreichen konnten. Die gesamten Ergebnisse der Evaluierung der FH JOANNEUM GmbH und des Templates, welches als ‘Accessibility Ready’ gekennzeichnet ist, wurden in einer Tabelle festgehalten. In diesen Tabellen wurden sowohl gute Umsetzungen, als auch Fehler besonders hervorgehoben. Für einfach zu behebende Fehler wurden ebenfalls Lösungsvorschläge angegeben. Zuletzt wurden die Ergebnisse auch in textueller Form und in einer vereinfachten Tabelle in dieser Arbeit festgehalten.Content management systems like WordPress enables people without training in design or web development to create websites quickly and cheaply. This is made possible for the users of these systems due to the use of so-called templates. However, this is also accompanied by a major concern regarding accessibility, as these templates do not have to be subject to any given standards. At the beginning of this thesis, necessary terms such as accessibility were defined. Likewise disabilities, which can affect the use of web pages negatively, were pointed out and divided into four categories. Then, three standards were presented that can be used to create accessible websites, or templates. These standards were translated from English into German by the author of this thesis and summarized. Subsequently, the four most used free WordPress templates from the category 'Food & Drink', as well as the only template of this category, which was tagged as 'Accessibility Ready', were evaluated for their accessibility. These evaluations were performed manually using the demo versions of the templates. Additionally, the website of FH Joanneum Ltd., which was also created with WordPress, was manually examined. The goal of the evaluation was to find out what level of compliance, according to the Web Content Accessibility Guidelines, these templates and the website can achieve. The evaluation showed that neither the examined templates nor the website of the FH Joanneum Ltd. could reach even the lowest level of conformance. The entire results of the evaluation of the website of FH Joanneum Ltd. and the template, which is tagged as 'Accessibility Ready', were noted in a table. In these tables, both good implementations and errors were highlighted. Suggested solutions were also given for errors that are easy to fix. Finally, the results were also recorded in textual form and in a simplified table in this thesis.eingereicht von: Darlene AntonioAbweichender Titel laut Übersetzung der Verfasserin/des VerfassersBachelorarbeit FH JOANNEUM 202
Performance Analysis of Wireless Communication FH-CDMA System Under a Fading Channel.
No full text隨著科技的進步，無線通訊系統和人們的生活息息相關。展頻多工系統，亦即編碼多工系統，已然成為無線科技中一項引人矚目的技術。跳頻分碼多工系統(FH-CDMA System)即利用分配不同的用戶的跳頻碼，讓多用戶可以同時使用同一頻帶傳送所需資料。
過去的跳頻系統效能分析，並沒有考慮因多數使用者產生碰撞(hit)所引發的影響，且權重消除(deletion)不會隨著碰撞次數的增多，而改變其機率大小。在這篇論文中，我們提出了一個新的方法，重新考慮了權重消除(deletion)的機率，使它能隨著碰撞的情形改變，並且修改了相關的式子，使我們的分析方法更接近真實的情形。我們利用此方法重新分析了Goodman’s FH-CDMA 系統，在我們的電腦分析中，其結果和我們的理論值相當接近，也證實了新的方法較舊的方法提供更好的分析結果。Code-division multiple access (CDMA) is one of the most successful methods accounting for the rapid technological advancement and increasing demand in wireless personal communications. The use of frequency hopping (FH) in CDMA wireless communication systems has been receiving attention significantly since the past decade. FH-CDMA is known to provide effective means in combating multipath fading due to its inherent frequency diversity. In previous performance analyses, the probability of deletion (caused by fading) does not depend on the number of collisions (or hits) caused by other simultaneous users in the FH-CDMA system. This results in overestimating the overall error probability. In this thesis, we propose a new method to derive the probability of deletion. The method uses the fact that multiple collisions in a chip can lessen the effect of deletion, lowering the probability of deletion and, in turn, the overall error probability. Afterwards, the new probability of deletion is applied to analyze the Goodman's MFSK/FH-CDMA system. Our result and numerical example show that the new method provides a more accurate analysis than the old method.1.Introduction……………………………………………1
1.1.Background……………………………………………1
1.1.1.Overview of DS-CDMA System……………………2
1.1.2.Overview of FH-CDMA System……………………3
1.2.Motivation and Outline of Thesis………………6
2.FH-CDMA Wireless Communication Systems…………8
3.Performance Analysis…………………………………13
4.Numerical Examples……………………………………26
5.Conclusions ……………………………………………31
Appendix A…………………………………………………32
Appendix B…………………………………………………34
References…………………………………………………3
Het ontwerp van een synchronisatiemethode voor een muitiplex-systeem volgens het FH-MFSK principe ten behoeve van dataoverdracht van een basisstation naar een aantal mobiele stations
No full textFrequency Hopping-Multiple Frequency Shift Keying (FH-MFSK) is een principe waarmee gegevens kunnen worden overgedragen in een mobiel communicatiesysteem voor meerdere gebruikers. Met behulp van Code Division Multiple Access (CDMA)-techniek is het mogelijk het effect van interferentie tussen de gebruikers onderling te beperken, In de mobiele communicatie heeft men te maken met diverse omgevingsinvloeden, zoals meerwegfading en interferentie. Het FH-MFSK principe biedt mogelijkheden de kwaliteit en net frequentierendement van de overdracht op een acceptabel niveau te brengen. Onderzocht is noe in een FH-MFSK systeem synchronisatie tot stand gebracht kan worden.Electrical Engineering, Mathematics and Computer ScienceTelecommunicatie- en Verkeersbegeleidingssysteme
Website accessibility : evaluating the WCAG conformance level of WordPress templates and the FH Joanneum GmbH's website
No full textDurch Content Management Systeme wie WordPress ist es auch Menschen ohne Ausbildung in Design oder Webentwicklung möglich, Webseiten schnell und günstig zu erstellen. Dies wird den BenutzerInnen dieser Systeme durch sogenannte Templates oder Vorlagen ermöglicht. Damit geht jedoch auch ein großes Problem bezüglich der Barrierefreiheit einher, da diese Templates nicht den gegebenen Standards unterliegen müssen. Zu Beginn dieser Arbeit wurden notwendige Begriffe wie Barrierefreiheit definiert. Ebenfalls wurden Behinderungen, welche die Benutzung von Webseiten negativ beeinflussen können, aufgezeigt und in vier Kategorien unterteilt. Daraufhin wurden drei Standards vorgestellt, mit deren Hilfe barrierefreie Webseiten, oder Templates, erstellt werden können. Diese Standards wurden von der Autorin aus dem Englischen ins Deutsche übersetzt und zusammengefasst. Anschließend wurden die vier meist genutzten, kostenlose WordPress Templates aus der Kategorie ‘Food & Drink’, sowie das einzige Template dieser Kategorie, welches als ‘Accessibility Ready’ gekennzeichnet wurde, auf ihre Barrierefreiheit untersucht. Diese Evaluierungen wurden manuell anhand der Demo-Versionen der Templates durchgeführt. Zusätzlich wird die Webseite der FH JOANNEUM GmbH, welche ebenfalls mit WordPress erstellt wurde, manuell untersucht. Ziel der Evaluierung war es herauszufinden welche Konformitätsstufe, nach den Web Content Accessibility Guidelines, diese Templates und die Webseite erreichen können. Die Evaluierung ergab, dass weder die untersuchten Templates, noch die Webseite der FH JOANNEUM GmbH auch nur die niedrigste Konformitätsstufe erreichen konnten. Die gesamten Ergebnisse der Evaluierung der FH JOANNEUM GmbH und des Templates, welches als ‘Accessibility Ready’ gekennzeichnet ist, wurden in einer Tabelle festgehalten. In diesen Tabellen wurden sowohl gute Umsetzungen, als auch Fehler besonders hervorgehoben. Für einfach zu behebende Fehler wurden ebenfalls Lösungsvorschläge angegeben. Zuletzt wurden die Ergebnisse auch in textueller Form und in einer vereinfachten Tabelle in dieser Arbeit festgehalten.Content management systems like WordPress enables people without training in design or web development to create websites quickly and cheaply. This is made possible for the users of these systems due to the use of so-called templates. However, this is also accompanied by a major concern regarding accessibility, as these templates do not have to be subject to any given standards. At the beginning of this thesis, necessary terms such as accessibility were defined. Likewise disabilities, which can affect the use of web pages negatively, were pointed out and divided into four categories. Then, three standards were presented that can be used to create accessible websites, or templates. These standards were translated from English into German by the author of this thesis and summarized. Subsequently, the four most used free WordPress templates from the category 'Food & Drink', as well as the only template of this category, which was tagged as 'Accessibility Ready', were evaluated for their accessibility. These evaluations were performed manually using the demo versions of the templates. Additionally, the website of FH Joanneum Ltd., which was also created with WordPress, was manually examined. The goal of the evaluation was to find out what level of compliance, according to the Web Content Accessibility Guidelines, these templates and the website can achieve. The evaluation showed that neither the examined templates nor the website of the FH Joanneum Ltd. could reach even the lowest level of conformance. The entire results of the evaluation of the website of FH Joanneum Ltd. and the template, which is tagged as 'Accessibility Ready', were noted in a table. In these tables, both good implementations and errors were highlighted. Suggested solutions were also given for errors that are easy to fix. Finally, the results were also recorded in textual form and in a simplified table in this thesis.eingereicht von: Darlene AntonioAbweichender Titel laut Übersetzung der Verfasserin/des VerfassersBachelorarbeit FH JOANNEUM 202
Two Novel Colorimetric Probes (5-HMBA-FH and 3-HMBA-FH) Based on Fluorescein for Copper(II) ion Detection
Full text linkTwo novel isomeric colorimetric probes are established for simultaneous determination of copper ions using 2-Hydroxy-5-methoxybenzaldehyde fluorescein hydrazone (5-HMBA-FH) and 2-Hydroxy-3-methoxybenzaldehyde fluorescein hydrazone (3-HMBA-FH). They are synthesized by reacting fluorescein hydrazide with 2-Hydroxy-5-methoxybenzaldehyde and 2-Hydroxy-3-methoxybenzaldehyde, respectively, and then characterized by 1H-NMR, 13C-NMR and Infrared spectrum. In addition of copper ions to the solutions of two novel colorimetric probes can generate the obviously peaks at 498 nm in UV-vis absorption spectra along with a rapid color change from colorless to dark yellow. The detection limits of the method for Cu2+ ion were 3.442 Ă 10-6 mol/L and 3.682 Ă 10-6 mol/L separately, for 5-HMBA-FH and 3-HMBA-FH. The additions of other metal ions hardly affect the copper ions determination. The proposed method was successfully applied to the analysis of Cu2+ ions in various samples. This method possessing high sensitivity, simplicity and minimized interfere will provide a great advantage in detecting copper ions in the environmental, food, medical applications.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
An Exploratory Study of Crisis PR Principles in Three Taiwanese Organizations
No full textNowadays, organizational crisis management is one area in which PR experts truly earn their keep. Accordingly, until 2001, around 50 to 70 percent of the largest profit-making organizations in the United States haven't made any disaster plans. In Taiwan, it may not surprise to learn that, nowadays some still failed to put plans in place in anticipation of a catastrophe. As a matter of the fact, there are more examples of organizations getting crisis management wrong than doing it right. When crisis strikes, most companies are unprepared and poorly handle the situation. The overall purpose of this study is to investigate how Taiwanese companies use crisis management principles in handling public opinions at five phases of a crisis: detection, preparation/prevention, containment, recovery, and learning. The research conducted within this study determines how effectively Taiwanese organizations have communicated their corporate value to their stakeholders
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