1,721,008 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Prospection of antifungal agents of agronomic interest in species of the genus Penicillium

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    The genus Penicillium has several species already identified as producers of bioactive molecules derived from their secondary metabolism, showing prominence in several biological activities of interest such as antifungal activity. More and more, several countries have been using microorganisms, especially fungi, as agents for the biocontrol of diseases caused by phytopathogenic fungi, since these are considered natural agents and with great efficiency in protecting economically valuable crops worldwide. Bearing in mind the concern with the use of techniques that aim to preserve cultures of economic value, such as the guarana crop, a plantation widely cultivated for commercialization in several industrial sectors in the state of Amazonas and harnessing the capacity of fungi, mainly of the genus Penicillium in producing bioactive substances and its ability to act as a biocontrol agent this work aims to verify the antifungal potential of different species of fungi of the genus Penicillium (MMSRG-020) in combating the phytopathogenic fungus Fusarium decemcellulare (MMSRG-110) through tests of antibiosis, as well as chemically analyzing the secondary metabolites involved in the activities to be discovered. Antibiosis assays showed that the fungus MMSRG-020 (Penicillium sp.) acted as a mycoparasite against the phytopathogenic fungus MMSRG-110 (Fusarium decemcellulare), preventing its growth and causing the phytopathogen to lose one of its main characteristics, which is the color of its mycelium, such activity demonstrates the ability of MMSRG-020 to act as an important biocontrol agent against the main phytopathogen of guarana through the process of mycoparasitism. The analysis by mass spectrometry showed that in the different culture media in which MMSRG-020 was cultivated, at retention point 6.28 it presented a mass value of 299.2 (m/z), identified as the 4-Aminophyscion molecule (C16H13NO5) , an anthraquinone, first recorded as a natural product isolated from the fungus Dermocybe canaria (order Agaricales) and which in this work was identified for the first time in the genus Penicillium, an identification that corroborates the elucidation of possible important biological activities arising from this anthraquinone. Keywords: Penicillium; secondary metabolism; biocontrol agentes; mass spectrometry.O gênero Penicillium possui diversas espécies já identificadas como produtoras de moléculas bioativas oriundas de seu metabolismo secundário, apresentando destaque em diversas atividades biológicas de interesse como a atividade antifúngica. Cada vez mais, diversos países vêm utilizando microrganismos, principalmente os fungos como agentes de biocontrole de doenças causadas por fungos fitopatogênicos, já que estes são considerados agentes naturais e com grande eficiência na proteção de culturas de valor econômico em todo o mundo. Tendo em vista a preocupação no emprego de técnicas que visem preservar culturas de valor econômico, como é o caso da cultura do guaraná, plantação amplamente cultivada para comercialização em diversos setores industriais no estado do Amazonas e atrelando a capacidade dos fungos, principalmente do gênero Penicillium em produzir substâncias bioativas e sua capacidade de atuar como agente de biocontrole este trabalho tem por objetivo verificar o potencial antifúngico de diferentes espécies de fungos do gênero Penicillium (MMSRG-020) no combate do fungo fitopatogênico Fusarium decemcellulare (MMSRG-110) através de ensaios de antibiose, bem como analisar quimicamente os metabólitos secundários envolvidos nas atividades a serem descobertas. Os ensaios de antibiose demonstraram que o fungo MMSRG-020 (Penicillium sp.) atuou como um micoparasita frente ao fungo fitopatogênico MMSRG-110 (Fusarium decemcellulare), impedindo o seu crescimento e fazendo com que o fitopatógeno perdesse uma de suas principais características que é a coloração de seu micélio, tal atividade evidencia a capacidade de MMSRG-020 em atuar como um importante agente de biocontrole frente ao principal fitopatógeno do guaraná através do processo de micoparasitismo. As análises por espectrometria de massas demonstraram que nos diferentes meios de cultura em que MMSRG-020 foi cultivado, este, no ponto de retenção 6.28 apresentou um valor de massa 299.2 (m/z), identificado como a molécula 4-Aminophyscion (C16H13NO5), uma antraquinona, primeiramente registrada como um produto natural isolado do fungo Dermocybe canaria (ordem Agaricales) e que neste trabalho foi identificada pela primeira vez no gênero Penicillium, identificação esta que corrobora para a elucidação de possíveis atividades biológicas importantes oriundas desta antraquinona. Palavras-chave: Penicillium; metabolismo secundário; agentes de biocontrole; espectrometria de massas

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Metabolomic analysis of annonaceae species occurring in Manaus by mass spectrometry

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    A medicinal plant is considered like any species that administered to man or animal, by any means or form, exerts some therapeutic function and due to the great use of these herbs, studies in search of their chemical substances were and are carried out continuously. The Annonaceae family is widely known for its alkaloids that are present in several species, however, there are still specimens whose chemical components have not been fully elucidated. Thus, the aim of this study was to comparatively recognize different species of plants from the Annonaceae family by means of mass spectrometry. For this, five plant species belonging to the genus Annona, Duguetia, Fusaea, Guatteria and Xylopia were collected, their extracts were obtained and analyzed by Liquid Chromatography coupled to High Resolution Mass Spectrometry (LC-HRMS/MS). Of the five plants, only the leaves of the species Guatteria discolor were analyzed and the results presented showed the presence of four alkaloid substances (puterine, oxoputerine, asimilobine and anonaine), the latter two being unpublished for this species. Among the identified molecules, only puterine has not yet had its biological activity elucidated, thus suggesting new studies for this substance. Keywords: Annonaceae, alkaloids, Guatteria discolor, aporphinic and oxoaporphinic.Considera-se planta medicinal toda espécie que administrada ao homem ou animal, por qualquer via ou forma, exerça alguma função terapêutica e devido ao grande uso dessas ervas, estudos em busca de suas substâncias químicas foram e são realizados continuamente. A família Annonaceae é amplamente conhecida pelos seus alcaloides que estão presentes em diversas espécies, entretanto, ainda há exemplares cujos componentes químicos ainda não foram totalmente elucidados. Deste modo, o objetivo deste estudo foi reconhecer comparativamente diferentes espécies de plantas da família Annonaceae por meio de espectrometria de massas. Para isso, foram coletadas cinco espécies de plantas pertencentes ao gênero Annona, Duguetia, Fusaea, Guatteria e Xylopia, seus extratos foram obtidos e analisados através da cromatografia líquida acoplado a espectrometria de massa de alta resolução (LC HRMS/MS). Das cincos plantas, somente as folhas da espécie Guatteria discolor foram analisadas e os resultados apresentados mostraram a presença de quatro substâncias alcaloídicas (puterina, oxoputerina, asimilobina e anonaína), sendo estas duas últimas inéditas para tal espécie. Dentre as moléculas identificadas, somente a puterina ainda não possui a sua atividade biológica elucidada, sugerindo assim novos estudos para essa substância. Palavras chave: Annonaceae, alcaloides, Guatteria discolor, aporfínicos e oxoaporfínicos

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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