102,398 research outputs found

    Finding New Ways to Treat Kidney Disease

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    Chronic kidney disease affects millions of people in the U.S. and worldwide; however, current treatments are not highly effective. Many factors contribute to chronic kidney disease, including diabetes, hypertension, autoimmune disorders, and others. Research in the lab of University of Utah Health investigator Donald Kohan, MD, PhD, used genetically engineered mice to help identify a peptide, endothelin-1, and its receptor, ETA, as key regulators of blood pressure and kidney function in health. Kohan and colleagues also helped determine that kidney ET-1 production is increased in many kidney diseases and, through activation of ETA receptors on most kidney cell types, leads to inflammation, scarring, and decreased kidney function. Together with national and international collaborators, they have translated these studies into clinical trials demonstrating that blocking the ETA receptor protects kidney function in individuals with type 2 diabetes mellitus. These trials with ETA receptor antagonists are now being extended into other forms of chronic kidney disease. Targeting the endothelin-1/ETA receptor system represents a promising approach to the treatment of chronic kidney disease

    PENGARUH MINAT MENONTON ANIME TERHADAP HASIL BELAJAR CHOUKAI-KAIWA SHOKYU KOHAN TAHUN 2023/2024

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    Sukmawati, D. G. (2024). Pengaruh Minat Menonton Anime terhadap Hasil Belajar Choukai- Kaiwa Shokyu Kohan Tahun 2023/2024. Skripsi. Jurusan Bahasa dan Sastra Asing. Fakultas Bahasa dan Seni. Universitas Negeri Semarang. Pembimbing Utama Dr. Rina Supriatnaningsih, M.Pd. Kata kunci : Minat, Anime, Hasil Belajar Bahasa Jepang, Choukai-Kaiwa Shokyu Kohan Seiring perkembangan zaman, dunia pendidikan perlahan-lahan mengalami kemajuan dalam bidang teknologi yang sekarang telah memasuki era 5.0 atau dikenal dengan Society 5.0. Adanya teknologi ini berdampak pada kemajuan dalam dunia pendidikan salah satunya pada media pembelajaran. Salah satu contoh media penunjang pembelajaran yang kerap digunakan di dunia pendidikan pada era ini yaitu animasi berupa anime yang berasal dari Jepang. Berkat kemajuan teknologi yang menghasilkan anime ini, banyak pemelajar bahasa Jepang yang menggunakan anime sebagai media penunjang pembelajaran dikarenakan dapat melatih menyimak dan berbicara dalam bahasa Jepang. Berdasarkan hasil studi pendahuluan yang diberikan kepada 47 mahasiswa semester dua angkatan 2023, 87,2% mahasiswa merasa senang menonton anime, kemudian 97,9% mahasiswa setuju bahwa menonton anime memberikan manfaat dalam pembelajaran bahasa Jepang terutama pada mata kuliah Choukai-Kaiwa Shokyu Kohan dengan persentase sebesar 80,9%. Berdasarkan hasil studi pendahuluan tersebut, maka peneliti tertarik untuk melakukan penelitian mengenai pengaruh minat menonton anime terhadap hasil belajar Choukai-Kaiwa Shokyu Kohan pada mahasiswa semester dua tahun 2023/2024. Penelitian ini bertujuan untuk mendeskripsikan ada atau tidaknya pengaruh minat menonton anime terhadap hasil belajar Choukai-Kaiwa Shokyu Kohan pada mahasiswa semester dua tahun 2023/2024 serta faktor apa saja yang memengaruhi minat menonton anime. Penelitian ini menggunakan metode penelitian deskriptif kuantitatif. Sampel dalam penelitian ini adalah mahasiswa semester dua angkatan 2023 sebanyak 62 mahasiswa yang terdiri dari 10 mahasiswa digunakan untuk uji reliabilitas angket dan 52 mahasiswa sebagai data penelitian. Metode pengumpulan data menggunakan angket dan dokumentasi. Metode angket digunakan untuk mendapatkan informasi mengenai minat menonton anime pada mahasiswa semester dua angkatan 2023 dan metode dokumentasi digunakan untuk mendapatkan nilai ujian tengah semester mata kuliah Choukai-Kaiwa Shokyu Kohan mahasiswa semester dua. Berdasarkan hasil analisis menggunakan uji regresi linier sederhana, menunjukkan bahwa terdapat hubungan antara minat menonton anime dengan hasil belajar Choukai-Kaiwa Shokyu Kohan yang termasuk dalam kategori sedang. Selain itu, terdapat pengaruh minat menonton anime terhadap hasil belajar Choukai-Kaiwa Shokyu Kohan pada mahasiswa semester dua dengan didapatkan nilai signifikansi sebesar 0,002 lebih kecil dari nilai signifikansi yang ditetapkan sebesar 0,05 yang artinya terdapat pengaruh minat menonton anime terhadap hasil belajar Choukai-Kaiwa Shokyu Kohan tahun 2023/2024 dengan besar pengaruh 18,3%. Adapun faktor yang memengaruhi minat menonton anime pada mahasiswa dibagi menjadi empat indikator dengan perolehan persentase rata-rata indikator perasaan senang dan perhatian masing-masing sebesar 85%, diikuti ketertarikan 82%, dan terakhir keterlibatan sebesar 75%

    MoS2 Nanosheets Uniformly Anchored on NiMoO4 Nanorods, a Highly Active Hierarchical Nanostructure Catalyst for Oxygen Evolution Reaction and Pseudo-Capacitors

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    Hierarchical nanostructures have attracted considerable research attention due to their applications in the catalysis field. Herein, we design a versatile hierarchical nanostructure composed of NiMoO4 nanorods surrounded by active MoS2 nanosheets on an interconnected nickel foam substrate. The as-prepared nanostructure exhibits excellent oxygen evolution reaction per-formance, producing a current density of 10 mA cm−2 at an overpotential of 90 mV, in comparison with 220 mV necessary to reach a similar current den-sity for NiMoO4. This behavior originates from the structural/morphological properties of the MoS2 nanosheets, which present numerous surface-active sites and allow good contact with the electrolyte. Besides, the structures can effectively store charges, due to their unique branched network providing accessible active surface area, which facilitates intermediates adsorptions. Particularly, NiMoO4/MoS2 shows a charge capacity of 358 mAhg−1 at a current of 0.5 A g−1 (230 mAhg−1 for NiMoO4), thus suggesting promising applications for charge-storing devices

    Effects of hydrolysis ageing on the performance and dimensional stability of glass-fiber reinforced polyamide 66

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    Results of an in-depth study of hydrolysis testing on the mechanical performance, weight change, and dimensional stability of injection moulded glass-fiber reinforced polyamide 66 automotive composites are presented. Composite and resin samples have been characterised after conditioning in water-glycol mixtures at 70°C, 120°C and 150°C for a range of times up to 1000 hours. The results reveal that hydrothermal ageing results in significant changes in the mechanical performance, weight, and dimensions of these materials. Mechanical performance after conditioning at different temperatures could be superimposed when considered as a function of the level of fluid absorbed by the composite matrix

    Una esperienza di erranza. Riflessioni a margine del IX Convegno internazionale di Filosofia ed educazione a Rio de Janeiro. Intervista a Walter Kohan. A cura di Gemma Bianca Adesso e Annalisa Caputo

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    From the 1st to the 5th of October, the 'IX International Conference of Philosophy and Education' took place at the State University of Rio de Janeiro (UERJ). Teachers from different Schools and Universities, students and researchers met to discuss together. And we discussed with Professor Walter Kohan (one of the organizers) about current events, public schools, wandering and human rights.Dall’1 al 5 ottobre 2018 si è svolto all’Università statale di Rio de Janeiro (UERJ) il ‘IX Convegno internazionale di filosofia ed educazione’ che ha visto confrontarsi docenti di diverse scuole e dell’università, studenti e ricercatori. Con il professor Walter Kohan (uno degli organizzatori) abbiamo discusso di attualità, scuola pubblica, erranza e diritti umani

    Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung

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    Dieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author-springer.pdf

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