117,313 research outputs found
Modelling the cost-effectiveness of pharmacotherapy compared with cognitive–behavioural therapy and combination therapy for the treatment of moderate to severe depression in the UK
Get PDFBackground.
The National Institute of Health and Care Excellence (NICE) in England and Wales recommends the combination of pharmacotherapy and psychotherapy for the treatment of moderate to severe depression. However, the cost-effectiveness analysis on which these recommendations are based have not included psychotherapy as monotherapy as a potential option. For this reason, we aimed to update, augment and refine the existing economic evaluation.
Methods.
We constructed a decision analytic model with a 27-month time horizon. We compared pharmacotherapy with cognitive behavioural therapy (CBT) and combination treatment for moderate to severe depression in secondary care from a healthcare service perspective. We reviewed the literature to identify relevant evidence and, where possible, synthesised evidence from clinical trials in a meta-analysis to inform model parameters.
Results.
The model suggested that CBT as monotherapy was most likely to be the most cost-effective treatment option a cost per QALY threshold above £22,000. It dominated combination treatment and had an incremental cost-effectiveness ratio of £20,039 per quality-adjusted life year compared to pharmacotherapy. There was significant decision uncertainty in the probabilistic and deterministic sensitivity analyses.
Conclusions.
Contrary to previous NICE guidance, the results indicated that even for those patients for whom pharmacotherapy is acceptable, CBT as monotherapy may be a cost-effective treatment option. However, this conclusion was based on a limited evidence base, particularly for combination treatment. In addition, this evidence cannot easily be transferred to a primary care setting
Sea Lavender (Heliotropium gnaphalodes L.): Identification and Uses
Get PDFSea lavender is a native plant found naturally along the Atlantic coast of central and south Florida. This 7-page document discusses this species’ identification and uses. Written by Stephen H. Brown, Marc S. Frank, and Andrew K. Koeser and published by the UF/IFAS Environmental Horticulture Department, August 2018.
http://edis.ifas.ufl.edu/ep56
Sea Lavender (Heliotropium gnaphalodes L.): Identification and Uses
No full textSea lavender is a native plant found naturally along the Atlantic coast of central and south Florida. This 7-page document discusses this species’ identification and uses. Written by Stephen H. Brown, Marc S. Frank, and Andrew K. Koeser and published by the UF/IFAS Environmental Horticulture Department, August 2018.
http://edis.ifas.ufl.edu/ep56
Sea Lavender (Heliotropium gnaphalodes L.): Identification and Uses
No full textSea lavender is a native plant found naturally along the Atlantic coast of central and south Florida. This 7-page document discusses this species’ identification and uses. Written by Stephen H. Brown, Marc S. Frank, and Andrew K. Koeser and published by the UF/IFAS Environmental Horticulture Department, August 2018.
http://edis.ifas.ufl.edu/ep56
Incorporating Woody Ornamentals into Residential Landscapes to Reduce Nutrient Leaching
No full textUrban landscapes in Florida are typically dominated by turfgrass monoculture, with ornamental landscape plants comprising only a small portion of the landscape. Incorporating more woody ornamentals into your landscape can reduce fertilization and irrigation demand and help reduce nutrient leaching losses from your yard—a combination that will help protect Florida’s water resources. This 3-page fact sheet was written by Drew C. McLean, Andrew K. Koeser, Amy L Shober, Zhixuan Qin, Gitta Hasing, and Richard C. Beeson, and published by the UF Department of Environmental Horticulture, July 2014
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
No full textIn this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Letter from unknown writer to Jesse L. Boyce
No full textLetter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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