1,359,460 research outputs found

    Aniridia and Boston KPro: Is It a Long-Term Option?

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    Purpose of Review: Aniridia is a complex ocular disorder that causes limbal stem cell deficiency determining progressive aniridic keratopathy and the loss of corneal transparency. Allogeneic limbal stem cell transplantation followed by penetrating keratoplasty can stabilize the ocular surface but requires prolonged systemic immunosuppression. The type-1 Boston Keratoprosthesis can be a valid alternative allowing faster visual recovery without the need for systemic immunosuppression. Recent Findings: Several studies have reported good visual outcomes and good retention rates for keratoprosthesis in aniridic patients. Nonetheless, concerns still exist regarding complications that might lead to irreversible loss of function, such as glaucoma progression or intraocular infection. Other complications include retroprosthetic membrane formation, hypotony, and device extrusion. The presence of macular pathology and prevalence of glaucoma are two factors that may affect final visual acuity outcomes in aniridic patients. Summary: Implantation of the type-1 Boston Keratoprosthesis for aniridic keratopathy has shown promising results. However, further studies are needed to provide more evidence regarding long-term survival and complications

    Welfare choices : a story of market forces and social progress

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    The implementation of market solutions has been widely attempted in many different parts of the public sector. This chapter concerns a groundbreaking social reform, which introduced personal assistants for ‘functionally impaired’ people. It was a far-reaching and liberating reform aimed at making disabled people part of society. It replaced collective institutional care with individual choice, in turn built on a number of market-oriented mechanisms. The reform, though, soon grew costly and has been plagued by fraud and public mistrust. The chapter discusses how ideas of market mechanisms are not equal to ready-made solutions; they may come ill-conceived and before long be in need of revision and negotiation. The chapter provides a case of a major Swedish social reform, which illuminates, first, an experimental full-scale policy implementation and, second, how market ideas easily become confused with and substituted for the idea of individual choice

    Larsson L, Kindgren H., Knutsson K., Loeffler D., Åkerlund A. dir. (2003) - Mesolithic on the Move

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    Barbaza Michel. Larsson L, Kindgren H., Knutsson K., Loeffler D., Åkerlund A. dir. (2003) - Mesolithic on the Move. In: Bulletin de la Société préhistorique française, tome 101, n°2, 2004. pp. 367-369

    Calicium episcalaris (Caliciaceae), a new lichen species from Sweden

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    A new species of lichens, Calicium episcalaris Tibell &amp; Knutsson, is described from  Sweden. It is one of few Calicium species being parasitic or ‘Jugendparasit’, occurring on Hypocenomyce scalaris (Ach.) M.Choisy growing on an old wooden building in South Sweden.</p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Topical corticosteroids and fungal keratitis: A review of the literature and case series

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    The management of fungal keratitis is complex since signs and symptoms are subtle and ocular inflammation is minimal in the preliminary stages of infection. Initial misdiagnosis of the condition and consequent management of inflammation with corticosteroids is a frequent occurrence. Topical steroid use is considered to be a principal factor for development of fungal keratitis. In this review, we assess the studies that have reported outcomes of fungal keratitis in patients receiving steroids prior to diagnosis. We also assess the possible rebound effect present when steroids are abruptly discontinued and the clinical characteristics of three patients in this particular clinical scenario. Previous reports and the three clinical descriptions presented suggest that in fungal keratitis, discontinuing topical steroids can induce worsening of clinical signs. In these cases, we recommend to slowly taper steroids and continue or commence appropriate antifungal therapy

    Evidence-based policing as a disruptive innovation: The Global Policing Database as a disruption tool

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    Evidence-based policing (EBP) is, arguably, one of the biggest contemporary watersheds in the history of policing (see Dunham and Alpert, 2015; Lum and Koper, 2015). In the language of Christensen’s (1997) theory of disruptive innovation, EBP is a policing knowledge process that is part of the broader digital reform movement across the world (Helbing, 2015), dislodging the incumbent craft-based mode of doing police business. The dislodging of this model – which relies on learning largely based on knowledge acquired through on-the-job, handson experience of police work – started over three decades ago with the onset of the professional era in policing (see Kelling and Moore, 1989). Yet the onset of EBP during the mid-1990s created new opportunities for the professionalisation of police, where scientific evidence started to be created by police and was placed directly in the hands of police and police policymakers. The establishment of police research collectives in the late 1970s (e.g., U.S. Police Executive Research Forum and Home Office Police Research Group), the proliferation of problemoriented policing starting in the early 1990s (see Scott, this volume), followed by the release of the U.S. report titled What Works, What Doesn’t and What’s Promising (Sherman et al., 1997), pinpoints the start of the EBP movement. Sherman et al.’s report arguably offered the first comprehensive review of the best available scientific evidence to guide criminal justice policy and practice, including policing. Fast forward nearly 20 years, and EBP continues on an upward trajectory and is an important catalyst in the dislodging of the incumbent craft model of policing

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Rikard From Trio featuring Erik Weissglas och Jonas Knutsson : En konsert

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    En konsert framförd av Rikard From Trio featuring Erik Weissglas och Jonas Knutsson den 29 oktober 2016 på Umeå Jazzfestival.Repertoar:"Sugar" (Stanley Turrentine)"Tootiema Is a Big Fine Thing" (Trad)"Play it back" (Dr. Lonnie Smith)"Mercy, mercy, mercy" (Joe Zawinul)"Hide and Seek" (Weissglas-From)"Skype Waltz" (Henryson-Weissglas)"Fired Up" (From)Weissglas var solist på alla stycken utom "Hide and Seek". </p
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