5,743 research outputs found
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Money piece by Timothy P. Agnew, chief executive officer of the Finance Author
No full textMoney piece by Timothy P. Agnew, chief executive officer of the Finance Authority of Maine, about the increased availability of credit for Maine\u27s small businesses
Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs
No full textBackground—Cardiovascular side effects associated with cyclooxygenase-2 inhibitor drugs dominate clinical concern. Cyclooxygenase-2 is expressed in the renal medulla where inhibition causes fluid retention and increased blood pressure. However, the mechanisms linking cyclooxygenase-2 inhibition and cardiovascular events are unknown and no biomarkers have been identified.
Methods and Results—Transcriptome analysis of wild-type and cyclooxygenase-2−/− mouse tissues revealed 1 gene altered in the heart and aorta, but >1000 genes altered in the renal medulla, including those regulating the endogenous nitric oxide synthase inhibitors asymmetrical dimethylarginine (ADMA) and monomethyl-L-arginine. Cyclo-oxygenase-2−/− mice had increased plasma levels of ADMA and monomethyl-L-arginine and reduced endothelial nitric oxide responses. These genes and methylarginines were not similarly altered in mice lacking prostacyclin receptors. Wild-type mice or human volunteers taking cyclooxygenase-2 inhibitors also showed increased plasma ADMA. Endothelial nitric oxide is cardio-protective, reducing thrombosis and atherosclerosis. Consequently, increased ADMA is associated with cardiovascular disease. Thus, our study identifies ADMA as a biomarker and mechanistic bridge between renal cyclooxygenase-2 inhibition and systemic vascular dysfunction with nonsteroidal anti-inflammatory drug usage.
Conclusions—We identify the endogenous endothelial nitric oxide synthase inhibitor ADMA as a biomarker and mechanistic bridge between renal cyclooxygenase-2 inhibition and systemic vascular dysfunction
Timothy Meyer serves as a contributing author for UN report
No full textAssistant Professor Timothy Meyer served as a contributing author for the United Nations Industrial Development Organization\u27s report titled Networks for Prosperity: Connecting Development Knowledge Beyond 2015. The document, which was released during November, analyzes the nexus between the global connectedness of a country and its economic success, sustainability and government effectiveness. Meyer was one of only approximately 20 academic and practical experts from around the world selected to serve as a contributor after a global call for proposals.
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REPROGENETICS: LAW, POLICY, AND ETHICAL ISSUES
No full textList of contributors -- Preface -- Pt. I. The historical and regulatory landscape -- Ch. 1. On drawing lessons from the history of eugenics / Diane B. Paul -- Ch. 2. Governmental regulation of genetic technology, and the lessons learned / Julie Gage Palmer -- Ch. 3. Oversight of assisted reproductive technologies: the last twenty years / Andrea L. Bonnicksen -- Pt. II. Ethical issues in reprogenetics -- Ch. 4. Market transactions in reprogenetics: a case for regulation / Suzanne Holland -- Ch. 5. Stem cells, clones, consensus, and the law / Timothy Caulfield -- Pt. III. International regulation of reprogenetics -- Ch. 6. The governance of reprogenetic technology: international models / Lori P. Knowles -- Ch. 7. Regulating reprogenetics in the United Kingdom / Andrew Grubb -- Ch. 8. The evolution of public policy on reprogenetics in Canada / Patricia A. Baird -- Pt. IV. Regulating reprogenetics in the United States / Ch. 9. A brief history of public debate about reproductive technologies: politics and commissions / Kathi E. Hanna -- Ch. 10. Possible policy strategies for the United States: comparative lessons / Alison Harvison Young -- Ch. 11. The development of reprogenetic policy and practice in the United States: looking to the United Kingdom / Gladys B. White -- Ch. 12. Reprogenetics and public policy: reflections and recommendations / Erik Parns and Lori P. Knowles -- Inde
Selected Contributions of Sister Mary Berenice Beck, O.S.F. to Nursing in the United States, 1923-1956
No full textby Sister M. Timothy Costello.Typescript.Thesis (M.S.N.)--Catholic University of America.Bibliography: leaves 44-47.Also available in microfilm
Morbidity and Mortality Weekly Report (MMWR)
No full text"The following CDC staff members contributed to this report: Denise T. Koo, Andrew G. Dean, Myra A. Montalbano, Carol M. Knowles, Deborah A. Adams, Timothy M. Copeland, Patsy A. Hall, Robert F. Fagan, Harry R. Holden, Gerald F. Jones, Clarence Lee Maddox, Division of Surveillance and Epidemiology, Epidemiology Program Office; Consultant: Willie J. Anderson, Office of the Vice President for Health Affairs, Emory University."Bibliography: p. 81-87
The Baptismal Liturgy of Theodore of Mopsuestia
No full textTimothy A. Curtin.Typescript.Thesis (S.T.D.)--Catholic University of America, 1971.Bibliography: leaves 368-393
Five minutes with Timothy Gowers: “academics can publish journals of the highest quality without a commercial entity”
No full textFields Medal-winning Cambridge mathematician Sir Timothy Gowers and a team of colleagues have recently launched a new editor-owned Open Access (OA) journal for mathematics. Discrete Analysis is an arXiv overlay journal, which means articles are submitted and hosted via the preprint server arXiv first. The journal coordinates peer-review and publishes via Scholastica with no cost to reader or author. Gowers reflects here on his vision for the future of editor-owned journals
First person – Timothy Cummins
No full textABSTRACT
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Timothy Cummins is the first author on ‘PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP’, published in Journal of Cell Science. Timothy is an Assistant Professor of Medicine at the University of Louisville School of Medicine Clinical Proteomics Center, which focuses on identifying biomarkers of kidney diseases by using quantitative mass spectroscopy.</jats:p
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