118,350 research outputs found
Portrait of Karen L. Knipe
This 1965 to 1966 portrait of a woman holding a sign reading Knipe Karen L is part of the Sherrill Studio Collection. George Dexter Sherrill (1879–1931) opened the first photography studio in Haywood County on Depot Street in downtown Waynesville in 1902. In 1906 his studio became the first Eastman Kodak franchise west of Asheville and the third in North Carolina. Sherrill’s photography roots began in Jackson County where he learned the art from his brother-in-law, A. L. Ensley. Beulah Eloise Ashe Ensley (1899-1991) apprenticed with Sherrill in 1917 and worked in the studio with her husband, Sherrill’s nephew, Ralph Ensley (1894-1975) until Ralph’s death. The Ensley’s demolished the original studio in 1943, dug the site to street level, and built an International style building
Portrait of Mattie H. Knipe
This 1965 to 1966 portrait of a woman holding a sign reading Knipe Mattie H is part of the Sherrill Studio Collection. George Dexter Sherrill (1879–1931) opened the first photography studio in Haywood County on Depot Street in downtown Waynesville in 1902. In 1906 his studio became the first Eastman Kodak franchise west of Asheville and the third in North Carolina. Sherrill’s photography roots began in Jackson County where he learned the art from his brother-in-law, A. L. Ensley. Beulah Eloise Ashe Ensley (1899-1991) apprenticed with Sherrill in 1917 and worked in the studio with her husband, Sherrill’s nephew, Ralph Ensley (1894-1975) until Ralph’s death. The Ensley’s demolished the original studio in 1943, dug the site to street level, and built an International style building
Portrait of Cynthia M. Knipe
This 1965 to 1966 portrait of a woman holding a sign reading Knipe Cynthia M is part of the Sherrill Studio Collection. George Dexter Sherrill (1879–1931) opened the first photography studio in Haywood County on Depot Street in downtown Waynesville in 1902. In 1906 his studio became the first Eastman Kodak franchise west of Asheville and the third in North Carolina. Sherrill’s photography roots began in Jackson County where he learned the art from his brother-in-law, A. L. Ensley. Beulah Eloise Ashe Ensley (1899-1991) apprenticed with Sherrill in 1917 and worked in the studio with her husband, Sherrill’s nephew, Ralph Ensley (1894-1975) until Ralph’s death. The Ensley’s demolished the original studio in 1943, dug the site to street level, and built an International style building
Portrait of Claudia H. Knipe
This 1965 to 1966 portrait of a woman holding a sign reading Knipe Claudia H is part of the Sherrill Studio Collection. George Dexter Sherrill (1879–1931) opened the first photography studio in Haywood County on Depot Street in downtown Waynesville in 1902. In 1906 his studio became the first Eastman Kodak franchise west of Asheville and the third in North Carolina. Sherrill’s photography roots began in Jackson County where he learned the art from his brother-in-law, A. L. Ensley. Beulah Eloise Ashe Ensley (1899-1991) apprenticed with Sherrill in 1917 and worked in the studio with her husband, Sherrill’s nephew, Ralph Ensley (1894-1975) until Ralph’s death. The Ensley’s demolished the original studio in 1943, dug the site to street level, and built an International style building
Portrait of Joan M. Knipe
This 1965 to 1966 portrait of a woman holding a sign reading Knipe Joan M is part of the Sherrill Studio Collection. George Dexter Sherrill (1879–1931) opened the first photography studio in Haywood County on Depot Street in downtown Waynesville in 1902. In 1906 his studio became the first Eastman Kodak franchise west of Asheville and the third in North Carolina. Sherrill’s photography roots began in Jackson County where he learned the art from his brother-in-law, A. L. Ensley. Beulah Eloise Ashe Ensley (1899-1991) apprenticed with Sherrill in 1917 and worked in the studio with her husband, Sherrill’s nephew, Ralph Ensley (1894-1975) until Ralph’s death. The Ensley’s demolished the original studio in 1943, dug the site to street level, and built an International style building
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
In this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Letter from unknown writer to Jesse L. Boyce
Letter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County
The DNA binding domain of the Varicella-zoster virus gene 62 protein interacts with multiple sequences which are similar to the binding site of the related protein of herpes simplex virus type 1
Varicella-zoster virus gene 62 encodes a protein with
predicted Mr of 140,000D (VZV 140k) that shares extensive predicted amlno add sequence homology with the major Immediate early (IE) transcrlptlonal regulator protein of herpes simplex virus type 1 (HSV-1) Vmw175. The integrity of highly conserved region 2 is essential for the DNA binding and transcrlptlonal regulatory functions of Vmw175. Similarly, an Insertion mutation in region 2 (codons 468-641) of 140k eliminates the transcrlptlonal repression and activation functions of this protein. We have expressed a
fragment of 140k which encompasses region 2 as a non-fusion polypeptlde in bacteria. This 140k DNA binding domain peptlde (codons 417-646) binds to numerous DNA sequences throughout the VZV gene 62 promoter region. It induces multiple regions of protection from DNase I digestion, flanked by sites of DNase I hypersensltivity. Several of the sites recognized can be considered to be divergent forms
of the consensus sequence which is recognized by Vmw175. However, by use of a panel of mutagenlzed probe fragments, we found that the 140k DNA binding domain was less sequence-specific than Vmw175 In Its Interactions with DNA. Consistent with this, the homologous Vmw175 DNA binding domain, and also Intact Vmw175, recognize the gene 62 binding sites much less efficiently than the 140k DNA binding domain. Also In contrast to the situation with Vmw175, the140k DNA binding domain failed to induce DNA
bending when occupying the binding sites In its own
promoter. Deletion analysis has mapped the minimal DNA binding domain of the VZV 140k protein, as measured in gel retardation analysis, to lie within residues 472 to 633. The differences in binding characteristics of the DNA binding domains of the homologous VZV 140k and HSV-1 Vmw175 IE proteins may account for the subtle differences In their
regulatory activities in transfection assays and during
virus growth In tissue culture
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