853 research outputs found
sj-docx-1-cpx-10.1177_21677026221101379 – Supplemental material for Change of Threat Expectancy as Mechanism of Exposure-Based Psychotherapy for Anxiety Disorders: Evidence From 8,484 Exposure Exercises of 605 Patients
No full textSupplemental material, sj-docx-1-cpx-10.1177_21677026221101379 for Change of Threat Expectancy as Mechanism of Exposure-Based Psychotherapy for Anxiety Disorders: Evidence From 8,484 Exposure Exercises of 605 Patients by Andre Pittig, Ingmar Heinig, Stephan Goerigk, Jan Richter, Maike Hollandt, Ulrike Lueken, Paul Pauli, Jürgen Deckert, Tilo Kircher, Benjamin Straube, Peter Neudeck, Katja Koelkebeck, Udo Dannlowski, Volker Arolt, Thomas Fydrich, Lydia Fehm, Andreas Ströhle, Christina Totzeck, Jürgen Margraf, Silvia Schneider, Jürgen Hoyer, Winfried Rief, Michelle G. Craske, Alfons O. Hamm and Hans-Ulrich Wittchen in Clinical Psychological Science</p
Dataset: Temporal recalibration in response to delayed visual feedback of active versus passive actions
No full text<p>Data set related to the manuscript: </p><p>Kufer, K., Schmitter, C. V, Kircher, T., Straube, B., 2023. Temporal recalibration in response to delayed visual feedback of active versus passive actions: An fMRI study. https://doi.org/10.21203/RS.3.RS-3493865/V1</p><p>Abstract:</p><p>The brain can adapt its expectations about the relative timing of actions and their sensory outcomes in a process known as temporal recalibration. This might occur as the recalibration of timing between the outcome and (1) the motor act (sensorimotor) or (2) tactile/proprioceptive information (inter-sensory). This fMRI recalibration study investigated sensorimotor contributions to temporal recalibration by comparing active and passive conditions. Subjects were repeatedly exposed to delayed (150ms) or undelayed visual stimuli, triggered by active or passive button presses. Recalibration effects were tested in delay detection tasks, including visual and auditory outcomes. We showed that both modalities were affected by visual recalibration. However, an active advantage was observed only in visual conditions. Recalibration was generally associated with the left cerebellum (lobules IV, V and vermis) while action related activation (active > passive) occurred in the right middle/superior frontal gyrus during adaptation and test phases. Recalibration transferred from vision to audition was related to action specic activations in the cingulate cortex, the angular gyrus and left inferior frontal gyrus. Our data provide new insights in sensorimotor contributions to temporal recalibration via the superior frontal gyrus and inter-sensory contributions mediated by the cerebellum.</p>
Visualization and quantification of disease progression in multiple system atrophy
No full textTo visualize and quantify disease progression in multiple system atrophy (MSA) from cerebellar type (MSA-C), we combined two magnetic resonance imaging (MRI) techniques, voxel-based morphometry (VBM) and 3D-based volumetry. Patients suffering from MSA-C (n = 14) were imaged twice with an interval of 2.0 +/- 0.2 years. We first applied VBM to map brain morphology changes between MSA patients and controls and to identify brain areas that showed a significant amount of atrophy. Using 3D-based volumetry, we confirmed that in MSA-C patients, the brainstem including medulla and pons, vermis and cerebellar hemispheres, caudate nucleus and putamen showed significant atrophy compared with controls. Next, we used 3D-based volumetry to analyze the atrophy rates. Atrophy rates in patients with MSA were significantly different from controls for putamen (- 11.4% +/- 2.6%/year), vermis (-12.3% +/- 2.9%/year), and cerebellar hemispheres (-6.6% +/- 1.1%/year). The results show that 3D-based MRI volumetry is a tool that allows the disease progression of MSA to be followed over a time period of 2 years and suggest that it may serve as a surrogate marker in clinical trials to measure disease progression. (C) 2006 Movement Disorder Society
Lion tiger stripes : neural correlates of indirect semantic priming across processing modalities
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Der Einfluss des Schizophrenie-Risikogens Dysbindin 1 auf die Gehirnaktivierung im bilateralen mittleren frontalen Gyrus während einer Arbeitsgedächtnisaufgabe bei gesunden Individuen
No full textDer Einfluss des DTNBP1-Schizophrenierisikogens auf Kognition und Persönlichkeit bei gesunden Probanden
No full textDer Einfluss des genetischen Neuregulin-1-Status auf Persönlichkeitsmerkmale und kognitive Variablen bei Gesunden
No full textGedächtniseffekte der Sprach- und Gestikintegration : kortikale und hippokampale Aktivierungen im Bezug zur Gedächtnisleistung
No full textDer Einfluss des Schizophrenie-Risikogens Dysbindin 1 auf die Gehirnaktivierung im bilateralen mittleren frontalen Gyrus während einer Arbeitsgedächtnisaufgabe bei gesunden Individuen
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