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Sensitivität und Spezifität des Screening-Messgerätes ApneaLink® im Vergleich zur Polysomnographie bei gesunden Kindern mit V.a. schlafbezogene Atmungsstörungen und Kindern bzw. Jugendlichen mit chronischen Erkrankungen welche mit einer erhöhten Inzidenz von schlafbezogenen Atmungsstörungen einhergehen
No full textZusammenfassung
Ziel: Das Ziel dieser Studie ist die Untersuchung der Sensitivität und Spezifität des ambulanten Screeninggeräts Apnea Link® im Vergleich zur Polysomnographie bei gesunden Kindern mit V.a. schlafbezogenen Atmungsstörungen und Kindern bzw. Jugendlichen mit chronischen Erkrankungen, welche mit einer erhöhten Inzidenz von schlafbezogenen Atmungsstörungen einhergehen.
Methoden: Apnea Link® ist ein tragbares ambulantes Screeninggerät, um Apnoen, Hypopnoen und Sauerstoff-Desaturationen während der Schlafzeit zu diagnostizieren. Seine Validierung bei Kindern ist Ziel dieser Studie, wohingegen dies mit einem vergleichbaren Gerät bei Erwachsenen bereits erfolgt ist Die Polysomnographie ist der diagnostische Goldstandard zur Auffindung schlafbezogener Atmungsstörungen bei Kindern und Erwachsenen. Während des gesamten Nachtschlafes der 60 geprüften Kinder und Jugendlichen, zwischen 0 und 22 Jahren, führten wir eine parallele Messung von Polysomnographie und Apnea Link durch. Die untersuchten Parameter waren: Gesamtschlafzeit, Apnea-Hypopnoe-Index, durchschnittliche O2-Sättigung (SaO2),minimale SaO2, Schlafzeit mit SaO2 weniger als 90%.
Ergebnisse: Diese Studie inkludiert 60 Patienten, 17 Mädchen und 43 Jungen, gesund oder mit chronischer Erkrankung, mit V.a. schlafbezogene Atmungsstörungen. Die Durchführung der Polysomnographie definiert bei 28 Patienten (47 %) die Diagnose OSA. In den ApneaLink® Messungen zeigten sich 29 Patienten als positiv und 31 als negativ klassifiziert. Die weitere Analyse des ambulanten Screeninggerätes ergab eine Sensitivität und Spezifität von 82 % und 84 %, mit einem negativen und positiven prädiktiven Wert von 84 % und 82 %. Die ApneaLink® Ergebnisse bezogen auf die Spezifität in der Gruppe von Kindern unter 10 Jahren (Spezifität 72 %) sind deutlich schlechter als in den anderen Gruppen, welche ältere Kinder und jugendliche Patienten einschliessen.
Zusammenfassung: Diese Ergebnisse weisen darauf hin, dass ein ambulantes Gerät wie ApneaLink® allein als Screeninginstrument unzureichend ist, um OSA bei Kindern unter einem Alter von 10 Jahren zu entdecken. Andere Screeningmethoden müssen daher in naher Zukunft noch identifiziert werden.Abstract
Purpose: The purpose of this study is to objectify the sensitivity and specificity of the ambulant screening device ApneaLink® in comparison to polysomnography in children with chronic diseases which are correlating with sleep disordered breathing, and healthy children with suspicion upon sleep disordered breathing.
Methods: ApneaLink® is a portable ambulant screening device to diagnose apneas, hypopneas and oxygen desaturations during sleeping time. Its validation in children is issue of this study whereas the same in grown ups is already done. Polysomnography is the diagnostic goldstandard in finding sleep disordered breathing during sleep in children and grown ups. During the hole night sleep of the 60 tested (reviewed) children, between 0 and 22 years, we accomplished a parallel measurement with polysomnography and ApneaLink® on them. The parameters which were investigated: hole sleeping time, apnea-hypopnea-index, average O2 saturation (SaO2), minimal SaO2, sleepingtime with SaO2 under 90%.
Results: This study included 60 patients, 17 girls and 43 boys, which where healthy or with chronical disease, with suspicion of having sleep disordered breathing. Polysomnography results determined 28 patients (47%) with a diagnosis of OSA. ApneaLink® results classified 29 patients as positive and 31 as negative. Further analysis of the positive and negative ambulant screening device results showed a sensitivity and specificity of 82 % and 84 %, with a negative and positive predictive value of 84% and 82%, respectively. Parts of the ApneaLink® results in the group of children under 10 years (specifity 72 %) were quite poorer than in the other groups, which included older children and adolescent patients.
Conclusions: These results suggest that an ambulant device like ApneaLink® alone is insufficient as a screeningtool to detect OSA in children under an age of 10. Other screening methods need to be identified in the near future.
Keywords: ApneaLink®, ambulant screening device, sleep disordered breathing, polysomnography, validatio
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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