429 research outputs found

    Describing Ammonoid Conchs

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    Introduction: Because ammonoid jaws are rare (Tanabe et al. 2015) and preserved soft parts as well as radulae (Klug and Lehmann 2015; Kruta et al. 2015) are even rarer, most paleontologists are limited in the available morphological information to the conch when describing ammonoids. Taking the great diversity and disparity as well as the over 300 Ma of the clade’s existence into account, it becomes obvious that the different ammonoid clades have divergent sets of characters requiring descriptive procedures adapted to the requirements

    Riukiaria mundyi Korsós, Nakamura & Tanabe, 2011, sp. n.

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    Riukiaria mundyi sp. n. Figs 4 –6, 14– 19. Holotype male (NSMT-My 379)— Japan, Southern Ryukyus, Yaeyama Group, Yonaguni-jima Island, Mt. Dunandake, primary forest, N 24.4577 ° E 122.9711 °, 146 m alt., 31 August 2009, leg. Z. Korsós & Y. Nakamura. Paratypes: 3 males, 5 females, 2 juvs. (RUMF, HNHM)—Same locality and date. 1 male, 1 female (RUMF)— Japan, Southern Ryukyus, Yaeyama Group, Yonaguni-jima Island, Adigara Cave area, near construction place, N 24.4599 ° E 122.9594 °, 44 m alt., 2 September 2009, leg. Z. Korsós & Y. Nakamura 2 females (NSMT-My 380)— Japan, Southern Ryukyus, Yaeyama Group, Yonaguni-jima Island, Arakawabana forest trail, 134 m, primary forest, N 24.4441 ° E 123.0107 °, 1 September 2009, leg. Z. Korsós & Y. Nakamura 4 males, 5 females, 3 juvs. (RUMF, HNHM)— Japan, Southern Ryukyus, Yaeyama Group, Yonaguni-jima Island, Kubura-bari, N 24 ° 27.4 ’ E 122 ° 56.6 ’, 50 m alt., rocky grassland, 14 February 2010, leg. R. & Z. Korsós Diagnosis. A member of the genus Riukiaria as defined by Shinohara (1977) and Tanabe and Shinohara (1996) with the simple, forceps-like male gonopod conformation. It differs from congeners first of all by its coloration in life (almost uniformly pinkish-orange), by its exclusive occurrence on a single island (Yonaguni-jima), and in details of gonopod morphology. FIGURES 14–16. Riukiaria mundyi sp. n. 14 = Anterior body part paratype male, dorsal view; 15 = Epiproct of paratype male, dorsal view; 16 = Sternum, coxa, and prefemur of 2 nd legpair of paratype male, posterior view. Scales 1 mm (14,15) and 0.5 mm (16). Etymology. The specific epithet is a patronym in honor of Mr. Imre Mundy (Budapest), a Hungarian engineer, long time friend and supporter of the first author (genitive, masculine). Description. Measurements: Body size generally smaller than in most other Riukiaria species. Length of males 36–42 mm, midbody paranotal width 7.5–8 mm, metatergal length 1.8–2 mm, collum width 6–6.6 mm, length 2.4–3 mm (n= 4). Female body length 36–41 mm, midbody paranotal width 7.8–8.6 mm, metatergal length 1.8–2 mm, collum width 6.3–7.1 mm, length 2.8–3.3 mm (n= 8). Kubura-bari population (see Remarks): Male body length 25–26 mm, midbody paranotal width 5.1–5.3 mm, metatergal length 1.2–1.3 mm, collum width 4.4– 4.6 mm, length 1.9–2.1 mm (n= 4). Female body length 30–31 mm, midbody paranotal width 6.3–6.8 mm, metatergal length 1.3–1.4 mm, collum width 5.2–5.5 mm, length 2.5–2.6 mm (n= 5). Color in life (Fig. 4): Whole body is almost uniformly light orange, pinkish, occasionally tending toward reddish or dark yellowish. Head, prozona, legs, and underside paler, 6 th segment of antennae, tibiae and tarsi whitish. On collum and each metatergum a slightly darker, almost brownish median patch, pronounced towards paranota as oval spots. On preserved specimens (70 % ethanol) the vivid color quickly disappears, only shadows of the abovementioned pattern remains. Coloration of males and females does not differ. Fluorescence in UV light strong (Figs 5–6), especially on prozona and underside, metazona are slightly greyish. Head smooth, epicranial suture distinct, 2 + 2 frontal setae, several setae scattered above clypeus, with 2 dense rows at its margin and on labrum. Antennae straight, first article globose, 2 nd slightly clavate, subequal with articles 3 –5, 6th longest, about 1.2 x longer than 5 th, 7 th small, slender, slightly longer than wide. Gnathochilarial stipites and lamellae linguales covered densely with short hairs, large, triangular mentum with smaller, distinct, median hair-field. Collum convex, smooth, shiny, lateral and posterior margin with weak ridge, lateral corners triangular, slightly directed caudad. Pro- and metaterga smooth without any traces of tubercles or punctuation, not even wrinkles. Posteriolateral edge of paranota 2–3 triangular, on 4 th and onwards strongly pointed caudad (Fig. 14). Pore formula normal, pores on paranota 5,7,9,10,12,13,15,16, 17, and 18, in median excavation of paranota (in lateral view). Sides between segments 6–13 perfectly parallel, segments 14–19 gradually tapering, posteriolateral projections become more pointed. Epiproct in dorsal view subtriangular (Fig. 15), in lateral view protruding over paraprocts, parallel-sided, slightly curved ventrad, with 7 + 7 setae, 3 + 3 of them sitting on knobs. Paraprocts strongly marginate with 2 + 2 setae, hypoproct with 1 + 1 setae on knobs. Midbody legs well separated (by 1.8–1.9 mm in males, 2.4–2.8 mm in females), sterna wide and smooth. Postgonopodal legs with moderately developed ventral spine on prefemur, increasingly stronger towards body end, femur about twice as long as prefemur, straight, postfemur crassate, tibia straight, both subequal in length and about 1 / 3 rd of femur, tarsus slender, about twice as long as tibia, claw (ca. 0.5 mm long) curved. Sexual characters: Male 2 nd legpair (Fig. 16) coxa with strong median projections about half as long as length of coxa, apically with membraneous tubules surrounded by strong setae, 1 + 1 macrosetae sitting at joint of prefemur (1 anteriorly, and 1 posteriorly). No other sternal or leg modification could be observed. Male gonopodal aperture on segment 7 wide, elliptical, about twice as wide as long, gonopods in situ usually deeply embedded, with acropodites crossing each other. Coxa (Figs 17–18, c) long, slender, about twice as long as wide, without apophysis but with small apophyseal macroseta (cm). Cannula normal, hidden on mesal side. Telopodite consists of two simple processes (Figs 17–18) forming a simple, forceps-like appearance typical for Riukiaria (Tanabe & Shinohara 1996), the shorter branch being the prefemoral process (pfp), growing proximally from the base of prefemur, the latter being thick and short, and densely covered with long hairs. Prefemoral process about 3 / 4 th of length of acropodite, devoid of any seta, knob, or additional process, flattened, parallel-sided, spatula-shaped, almost transparent. Acropodite (as a continuation of prefemur) long, scythe-shaped, arched proximally towards prefemoral process, with its slightly broadened to triangular, pointed tip (s) almost bending back to that. Distinction between prefemur and acropodite indefinite, hairs becoming scarcier at about 1 / 3 rd of total length, but about half length still a strong macroseta (ms) on lateral side of acropodite. Prostatic groove runs straight medially along mesal side of acropodite, and ends indistinctly on its pointed tip. Female cyphopods (Fig. 19) closely packed behind 2 nd legpair, in large, ∞-shaped aperture, valves (v) are oval, nearly as high as wide, densely setose, operculum (op) on lateral side small, less than half as high as valves, with fewer and shorter but stronger setae, receptacles (r) embracing valves both anteriorly and posteriorly, subrectangular, with several series of short hairs only along ventral margin. Distribution. R. mundyi sp. n. is restricted to Yonaguni-jima Island, the southwesternmost member of the Yaeyama Island Group, southern Ryukyus, Okinawa Prefecture, Japan. Remarks. Yonaguni-jima island, the type locality of R. mundyi sp. n., is situated about 100 km east of Taiwan, and 80 km west of Iriomote-jima, another member of the Yaeyamas. On two of this latter island group, Iriomotejima and Ishigaki-jima islands, another species, R. chelifera, occurs. It is slightly larger (body length 45 mm), and its color pattern is different: head, antennae, proterga, large part of metaterga anteriorly dark brown or grey, posterior margin, paranota, tip of epiproct, and legs yellow. This is in strong contrast with the uniformly orange-yellow color of the new species. Male gonopods also differ, acropodite and prefemoral process being straight, slender, and almost equal in length, as opposed to the longer and curved acropodite with macroseta in R. mundyi sp. n. Comparison to the possible Taiwanese species, R. cohaesiva, R. contigua, and R. uraensis (from the region of Taipei, Wulai), all inadequately described and poorly illustrated by Wang (1956, 1957), is impossible without freshly collected material. Specimens of the new species in Yonaguni-jima were mostly collected along the edge of natural, deciduous forests, mostly in moist litter under the large leaves of Alocasia odora, but also close to human-disturbed areas like abandoned construction sites, ruined cave entrances etc. Adult specimens were collected at the locality Kuburabari, too, which is actually a pasture for the native, endemic race of horse (the Yonaguni pony), and these specimens were distinctly smaller than members of the other populations. This is perhaps due to that relatively harsh environment, the wind-swept rocky grassland on the western side of the island, generally poor in organic litter. The species was mentioned and illustrated as an undescribed Riukiaria from Yonaguni-jima island by Tanabe (2005). It was included into the Red Data Book of threatened wildlife of Okinawa and, though categorized as ’data deficient’ (DD), its habitat was proposed for preservation. According to our observations, the species is not confined to any characteristic or undisturbed biotope on Yonaguni-jima Island so perhaps habitat conservation is not the best approach, but considering that the total area of the island itself is only 28.8 square kilometers, the populations of the new and unique species are indeed worthy of legal protection.Published as part of Korsós, Zoltán, Nakamura, Yasuyuki & Tanabe, Tsutomu, 2011, Two new millipede species of the genus Riukiaria (Diplopoda, Polydesmida, Xystodesmidae) endemic to the Ryukyu Archipelago, Japan, pp. 55-68 in Zootaxa 2877 on pages 62-66, DOI: 10.5281/zenodo.27756

    Letter from Dominguez Estate Company to Mr. Charles Saunders, March 19, 1942

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    Letter refers to the transfer of a lease from former lessee, Shisuka Tanabe Motoyasu to Charles Saunders

    The Representation of Disabilities in Social Life in the Stort Story “Josee, the Tiger and the Fish”

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    The author seiko Tanabe reads two things: disability and gender for women. Josee's disability is used by Seiko Tanabe to highlight the social and stigma of disability, experienced by marginalized groups in Japanese culture. However, this is not just a story about “the life of a disabled person” it is a story about human beings struggling to label them selves amidst the pressures of society. Seiko Tanabe also highlights gender as one of the causes of Josee's difficulties in life because Japanese culture emphasizes the role of a woman such as the female traditional role, female sexuality, and female physical disability. However, Josee remains resilient in achieving her dreams despite the many challenges that make her want to give up. The researcher concluded the author Seiko Tanabe represents Josee as having obstacles that limit her from participating in social life like normal people in general

    Variability in immune infiltrates and HLA expression in cholangiocarcinoma

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    230 Background: Cholangiocarcinoma continues to have a dismal prognosis. The lack of effective therapy prompted us to determine whether patients develop an immune response against their own tumors. The aim of this study is to evaluate the CD8 infiltrate and expression of HLA class I antigen processing machinery (APM) components in cholangiocarcinoma. The HLA class I antigen processing machinery (APM) components play a crucial role in expression of HLA class I tumor antigen derived peptide complexes. These complexes mediate the recognition of tumor cells by cognate T cells. Defects in the expression of HLA class I APM components by tumor cells suggests that the infiltrating lymphocytes impose selective pressure on tumor cells. This selective pressure would facilitate the outgrowth of tumors by escaping T cell recognition. Methods: Retrospective review of clinicopathologic factors was performed for 18 peripheral cholangiocarcinomas. Formalin fixed, paraffin embedded tumors were evaluated for the content of lymphocyte infiltrates and for the expression of HLA class I APM components. Results: Eighteen patients underwent a partial hepatectomy for peripheral cholangiocarcinoma of whom 10 were female. Median age was 63yo. The majority of patients had node negative tumors (10/12). All tumors had lymphocytic infiltration. Median number of lymphocytes in the fibrous septae between tumor lobules was 42 CD8 T cells per 10 high power field, but only 4 CD8 T cells within tumor lobules. HLA class I APM components was defective and not detected in three tumors, all of which were poorly differentiated. HLA expression was down regulated in 9 tumors. HLA expression was in normal range in the remaining 6 tumors. Median overall survival has not been reached. Conclusions: Lymphocytic infiltrates were seen in all resected cholangiocarcinoma specimens. The loss of HLA class I APM component expression in cholangiocarcinoma suggests that infiltrating lymphocytes reflect a patient’s immune response to his/her tumor. This information provides a sound rationale to consider immunotherapy in the treatment of cholangiocarcinoma, specifically with antibodies to check point molecules which enhance patients’ immune response against his own tumors. </jats:p

    KONFLIK BATIN TOKOH YUICHI TANABE PADA NOVEL 'KITCHEN' KARYA BANANA YOSHIMOTO

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    Manusia akan berusaha memutuskan pilihan terbaik dalam hidupnya. Namun pada kenyatannya manusia kerap kali menghadapi kebimbangan dalam menentukan mana keputusan yang baik atau buruk yang pada akhirnya memicu konflik batin dalam dirinya. Konflik batin sering terjadi pada diri tiap orang, contoh paling sederhana adalah ketika seseorang ingin melanjutkan tidurnya di pagi hari namun ia sadar ia harus bangun dan berangkat bekerja. Jika ia memilih tidur ia akan terlambat bekerja, jika ia memilih bangun ia akan bekerja dalam keadaan masih mengantuk. Dalam hal ini tidur disebut dengan gagasan menyenangkan sedangkan bangun untuk bekerja disebut dengan gagasan tidak menyenangkan. Gagasan mana yang akan dipilih ini tentunya memiliki konsekuensinya masing-masing. Penulis mengambil contoh konflik batin yang digambarkan secara mendetail melalui karya sastra berupa novel berjudul Kitchen karya Banana Yoshimoto. Penulis menemukan penggambaran konflik yang dialami oleh tokoh bernama Yuichi Tanabe pada novel ini. Metode yang digunakan dalam pengambilan data adalah studi literatur. Tujuan penulisan makalah ini adalah menemukan bentuk dari konflik batin yang dialami Yuichi lalu pilihan mana yang akhirnya diputuskan Yuichi ketika mengalami konflik tersebut. Ditemukan 19 data berisi konflik batin yang dialami Yuichi, dan 14 di antaranya merupakan pilihan dengan sifat tidak menyenangkan. Hal ini disebabkan Yuichi punya pengalaman traumatik karena meninggalnya Eriko, ayah kandung Yuichi yang mengubah dirinya menjadi wanita. Pada akhirnya konflik batin yang dialami Yuichi sirna karena Yuichi membuka dirinya terhadap tokoh utama novel ini yaitu gadis bernama Mikage Sakurai. ******** Humans will try to decide the best choice in life. But in reality, humans often face indecision in determining which decision is good or bad, which in turn triggers inner conflict within themselves. Inner conflict often occurs in everyone, the simplest example is when someone wants to continue sleeping in the morning but he realizes he has to get up and go to work. If he chooses to sleep he will be late for work, if he chooses to wake up he will work while still sleepy. In this case sleeping is called a pleasant idea while getting up for work is called an unpleasant idea. Which idea to choose has its own consequences. The author takes an example of inner conflict that is described in detail through a literary work in the form of a novel entitled Kitchen by Banana Yoshimoto. The author finds the depiction of conflict experienced by a character named Yuichi Tanabe in this novel. The method used in data collection is literature study. The purpose of writing this paper is to find the form of inner conflict experienced by Yuichi and then which choice Yuichi finally decided when experiencing the conflict. Found 19 data containing inner conflict experienced by Yuichi, and 14 of them are choices with unpleasant properties. This is because Yuichi had a traumatic experience due to the death of Eriko, Yuichi's biological father who turned into a woman. In the end, the inner conflict experienced by Yuichi disappeared because Yuichi opened himself to the main character of this novel, a girl named Mikage Sakurai

    Letter from Thoburn T. Brumbaugh, Executive Secretary, The Detroit Council of Churches, to E.D. Kohnlstedt, Executive Secretary, Home Missions Section, Methodist Board of Missions, November 4, 1943

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    Typed correspondence from Thoburn T. Brumbaugh, Executive Secretary of The Detroit Council of Churches, Five Hundred Churches Demonstrating Christian Unity to Dr. E. D. Kohnlstedt, Executive Secretary of the Home Missions Section, Methodist Board of Missions. The letter discusses Rev. Shigeo Tanabe and his work in Detroit for the Methodist Church.The Bishop James Chamberlain Baker Collection includes letters, documents, and articles about Japanese Americans during World War II. Subjects in the collection include Japanese Americans mass removal, Pearl Harbor and the aftermath, religion, and support from the non-Japanese American community. The collection was digitized and made accessible online by CSUDH Gerth Archives and Special Collections

    Abstract 5248: Pioglitazone prevents hepatocellular carcinoma development in a rat model of cirrhosis

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    Abstract Introduction: Advanced hepatocellular carcinoma (HCC) is a leading cause of mortality worldwide with limited treatment options. There is a readily identifiable cohort of cirrhosis patients at risk and they are ideal candidates for chemoprevention. Anti-hyperglycemic agents have garnered interest for their potential anti-fibrotic as well as chemo-preventive effects. Pioglitazone, a selective PPAR-γ agonist, has been shown to reduce non-alcoholic steatohepatitis (NASH), but its role as an anti-fibrotic and chemopreventive agent has yet to be elucidated. The hypothesis of this study is that Pioglitazone reduces cirrhosis and subsequent HCC development in rats with diethylnitrosamine (DEN)-induced cirrhosis. Methods: Male Wistar received DEN 50mg/kg by intraperitoneal injection. DEN injury reliably recapitulates histological and molecular features of human HCC development with induction of hepatic fibrosis at 8 weeks, cirrhosis at 12 weeks, and HCC by 18 weeks. DEN-injured rats were randomized to receive oral gavage of pioglitazone at 3mg/kg/day (n=9) or vehicle control (n=9). Initiation of pioglitazone coincided with the development of liver fibrosis at 8 weeks. All animals were sacrificed at 18 weeks. Results: As expected, repeated injections of DEN in rats resulted in progressive fibrosis, cirrhosis, followed by HCC formation. Treatment with pioglitazone resulted in a 56% reduction of surface nodules relative to treatment with vehicle (7.4±4.9 vs. 17±7; p&amp;lt;0.005). Liver sections were stained by picrosirius red to assess fibrosis and pioglitazone significantly reduced collagen deposition in DEN-injured rats (collagen proportional area = 3.2±1.8% vs. 9.2±2%; p&amp;lt;0.035). This histologic observation was further confirmed by gene expression analysis with reductions in collagen-I, α-smooth muscle actin, and transforming growth factor beta in rats treated with pioglitazone. Finally, weekly injection of DEN also caused a significant decrease in overall body weight in comparison to untreated rats (398.1±60 vs. 598±46 grams; p&amp;lt;0.015), and pioglitazone treatment resulted in a trend for better protection of body weight relative to vehicle (398.1±60 vs. 427.5±56.3 grams). Conclusion: Overall our data supports the hypothesis that the anti-diabetic agent pioglitazone may be repurposed as a drug to reduce fibrosis and prevent HCC. This could be beneficiary in patient management given the low cost as well as minimal side effects. Citation Format: Shen Li, Sarani Ghoshal, Gunisha Arora, Derek J. Erstad, Michael Lanuti, Kenneth K. Tanabe, Bryan C. Fuchs. Pioglitazone prevents hepatocellular carcinoma development in a rat model of cirrhosis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5248. doi:10.1158/1538-7445.AM2017-5248</jats:p

    ON TANABE KUNIO`S ARTICLE “FAMILIARIZING WITH THE ACHIEVEMENTS, LEARNING FROM OUR PIONEERS. VASILIY YEROSHENKO: STAYING IN JAPAN AND HIS FRIENDS

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    The article written by the blind Masseur and Esperantist Mr. Tanabe Kunio and is translated into Russian in the year of the author’s 75th anniversary with his permission. The study, first published in 2013, is a modern evidence of V.J. Eroshenko’s activity and experience of staying in Japan namely what’s considered to be the most important for the blind. Like Vasily Eroshenko, Mr. Tanabe Kunio, who is a graduate of the Tokyo School for the Blind, is a masseur and Esperantist, so his experience is somewhat unique. The author’s attention is focused on what had been already achieved by the predecessors and, thus, could be repeated, and perhaps, improved. That’s why, the history development of the blind social movement in different countries is extremely significant for all modern blind people by following an example of the life achievements of their predecessors. This translation expands the theme of the years spent by Vasily Yeroshenko in Japan, initiated by Mrs. Isaki Michiko, a former teacher at the Tokyo School for the Blind, in her article “Eroshenko and the Tokyo Blind School”. However, it should not be viewed one-sidedly without taking into account the experience of the blind themselves. Fortunately, it was quite unique when sighted and blind researchers worked on the study of the archives of the Tokyo School for the Blind simultaneously and in a rather narrow circle. In such a cooperation, small groups of sighted and blind scholars were absolutely reasonable. Therefore, the blind scolars could bring together information from raised (Braille) manuscripts and publications that are unobtainable to sighted; and vice versa sighted ones gathered information from ordinary handwritten and printed sources inaccessible to the blind. It apeared that almost semultaneously studies of sighted and blind authors were written on the same historical material. This phenomenon is unique and gives us the opportunity to consider two articles as a kind of diptych, where one can see a number of nuances that would otherwise go unnoticed. The attention of the blind author Tanabe Kunio is attracted by Eroshenko’s activism, perseverance and mobility, as well as his ability to achieve goals, that is, the experience of the blind man surviving in extreme conditions, such as persecution, active participation in the socialist movement, arrests and repeated expulsions. Close attention also should be paid to the conclusion of the article – which is visually impaired or unsighted should not blindly imitate the sighted people, rejecting their own special needs and requirements. The extreme value and significance of V.J. Eroshenko as a blind activist for the blind people in Japan in the early 20th and in the first third of the 21st century remains the same – he acted precisely as a blind both among the blind and among the sighted. A tangible emphasis on the role of Christianity and its ideas in forming personal activism and a network of organizations supporting the blind in Japan should as well be highlighted in the proposed article. This subject was not for consideration for almost a century, however, lately it has become increasingly topical. The researchers of the International Research Group “Vasily Eroshenko and his time” are preparing an Internet conference “The Gospel and Eroshenko”, which will be held in the form of submitting and publishing the materials in 2020–2022, timed to the 130th jubilee from Eroshenko’s birth and the 70th death anniversary of the writer
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