1,720,960 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Učinak liječenja analozima prostaglandina F2 na proliferaciju i MAPK/ERK signaliziranje u tkivu spojnice bolesnika s glaukomom
No full textObjectives: Our study aimed to investigate the proliferation and activation of MAPK/ERK
signaling in the conjunctival cells of glaucoma patients who received PGF2 analogs in their
treatment and those without PGF2 analog treatment. We hypothesized that the patient group
treated with PGF2 analogs would show increased conjunctival cellular proliferation,
MAPK/ERK activation, and a positive correlation between those two processes.
Material and methods: Conjunctival samples were collected during deep sclerotomy
procedures for the treatment of glaucoma and subsequently processed by standard preparation
procedures for tissues before sectioning. Following immunofluorescence staining for Ki-67 and
P-ERK1/2, the sections were examined by digital image analysis to quantify the emitted
fluorescent signals. For the evaluation of statistically significant differences between the
expression of the tested proteins in our sample groups, we used a two-way analysis of variance
with Tukey’s post hoc test.
Results: We found an increased proliferation rate, measured by Ki-67 expression, in the
conjunctival cells of glaucoma patients treated with PGF2 analogs compared to patients without
PGF2 analog treatment. The same trend was present when analyzing the activation of the
MAPK/ERK pathway by measuring the expression of P-ERK1/2. Cellular proliferation and
MAPK/ERK activation were markedly higher in the conjunctival epithelium compared to the
stroma. There was no significant correlation between the proliferation rate and activation of
MAPK/ERK signaling in the conjunctival cells of our samples.
Conclusions: Our study has demonstrated a significant increase in conjunctival epithelial and
stromal cell proliferation and activation of the MAPK/ERK pathway in glaucoma patients
treated with PFG2 analogs. However, these two processes were not significantly correlated,
indicating that MAPK/ERK activation may have other effects on the conjunctiva. Future studies
on other PG-associated signaling pathways could elucidate the mechanism of increased
proliferation in the conjunctiva and lead to potential novel targets for treating the side effects
of PGF2 analog treatment.Ciljevi: Cilj našeg istraživanja bio je odrediti stopu proliferacije i aktivacije mitogenima
aktivirane protein kinaze / kinaze regulirane izvanstaničnim signalima (MAPK/ERK) signalnog
puta u stanicama spojnice bolesnika s glaukomom koji su tijekom liječenja primali analoge
prostaglandina F2 (PGF2), odnosni onih koji nisu liječeni analozima PGF2. Pretpostavili smo
da će skupina bolesnika liječena analozima PGF2 pokazati povećanu proliferaciju i aktivaciju
MAPK/ERK signalnog puta u stanicama spojnice te pozitivnu korelaciju između ta dva procesa.
Materijali i metode: Uzorci spojnica prikupljeni su tijekom provođenja zahvata duboke
sklerotomije za liječenje glaukoma i naknadno obrađeni standardnim postupcima za obradu
tkiva prije izrade rezova. Nakon imunofluorescencijskog bojenja na Ki-67 i fosforilirani
ERK1/2 (P-ERK1/2), provedena je digitalna analiza slika u svrhu kvantifikacije fluorescentnih
signala. Za procjenu statistički značajnih razlika između izražaja ispitivanih proteina u našim
uzorcima koristili smo dvosmjernu analizu varijance s Tukeyjevim post hoc testom.
Rezultati: Pronašli smo povećanu stopu proliferacije, mjerenu izražajem Ki-67, u stanicama
spojnice bolesnika s glaukomom liječenih analozima PGF2 u usporedbi s pacijentima bez
liječenja analozima PGF2. Isti trend bio je prisutan kada se analizirala aktivacija MAPK/ERK
signalnog puta mjerenjem izražaja P-ERK1/2. Stanična proliferacija i aktivacija MAPK/ERK
signalnog puta bili su značajno veći u epitelu spojnice u usporedbi sa stromom. Nije bilo
značajne povezanosti između stope proliferacije i aktivacije MAPK/ERK signalnog puta u
stanicama spojnice naših uzoraka.
Zaključci: Naše je istraživanje pokazalo značajno povećanje proliferacije epitelnih i stromalnih
stanica spojnice i aktivaciju MAPK/ERK signalnog puta u bolesnika s glaukomom liječenih
analozima PFG2. Međutim, nije postojala značajna povezanost ova dva procesa što ukazuje da
aktivacija MAPK/ERK signalnog puta vjerojatno ima druge učinke na spojnicu. Daljnja
istraživanja o drugim signalnim putevima povezanim s prostaglandinima mogla bi razjasniti
mehanizam povećane proliferacije u spojnici te dovesti do potencijalnih novih meta za liječenje
nuspojava analoga PGF2
Učinak liječenja analozima prostaglandina F2 na proliferaciju i MAPK/ERK signaliziranje u tkivu spojnice bolesnika s glaukomom
No full textObjectives: Our study aimed to investigate the proliferation and activation of MAPK/ERK
signaling in the conjunctival cells of glaucoma patients who received PGF2 analogs in their
treatment and those without PGF2 analog treatment. We hypothesized that the patient group
treated with PGF2 analogs would show increased conjunctival cellular proliferation,
MAPK/ERK activation, and a positive correlation between those two processes.
Material and methods: Conjunctival samples were collected during deep sclerotomy
procedures for the treatment of glaucoma and subsequently processed by standard preparation
procedures for tissues before sectioning. Following immunofluorescence staining for Ki-67 and
P-ERK1/2, the sections were examined by digital image analysis to quantify the emitted
fluorescent signals. For the evaluation of statistically significant differences between the
expression of the tested proteins in our sample groups, we used a two-way analysis of variance
with Tukey’s post hoc test.
Results: We found an increased proliferation rate, measured by Ki-67 expression, in the
conjunctival cells of glaucoma patients treated with PGF2 analogs compared to patients without
PGF2 analog treatment. The same trend was present when analyzing the activation of the
MAPK/ERK pathway by measuring the expression of P-ERK1/2. Cellular proliferation and
MAPK/ERK activation were markedly higher in the conjunctival epithelium compared to the
stroma. There was no significant correlation between the proliferation rate and activation of
MAPK/ERK signaling in the conjunctival cells of our samples.
Conclusions: Our study has demonstrated a significant increase in conjunctival epithelial and
stromal cell proliferation and activation of the MAPK/ERK pathway in glaucoma patients
treated with PFG2 analogs. However, these two processes were not significantly correlated,
indicating that MAPK/ERK activation may have other effects on the conjunctiva. Future studies
on other PG-associated signaling pathways could elucidate the mechanism of increased
proliferation in the conjunctiva and lead to potential novel targets for treating the side effects
of PGF2 analog treatment.Ciljevi: Cilj našeg istraživanja bio je odrediti stopu proliferacije i aktivacije mitogenima
aktivirane protein kinaze / kinaze regulirane izvanstaničnim signalima (MAPK/ERK) signalnog
puta u stanicama spojnice bolesnika s glaukomom koji su tijekom liječenja primali analoge
prostaglandina F2 (PGF2), odnosni onih koji nisu liječeni analozima PGF2. Pretpostavili smo
da će skupina bolesnika liječena analozima PGF2 pokazati povećanu proliferaciju i aktivaciju
MAPK/ERK signalnog puta u stanicama spojnice te pozitivnu korelaciju između ta dva procesa.
Materijali i metode: Uzorci spojnica prikupljeni su tijekom provođenja zahvata duboke
sklerotomije za liječenje glaukoma i naknadno obrađeni standardnim postupcima za obradu
tkiva prije izrade rezova. Nakon imunofluorescencijskog bojenja na Ki-67 i fosforilirani
ERK1/2 (P-ERK1/2), provedena je digitalna analiza slika u svrhu kvantifikacije fluorescentnih
signala. Za procjenu statistički značajnih razlika između izražaja ispitivanih proteina u našim
uzorcima koristili smo dvosmjernu analizu varijance s Tukeyjevim post hoc testom.
Rezultati: Pronašli smo povećanu stopu proliferacije, mjerenu izražajem Ki-67, u stanicama
spojnice bolesnika s glaukomom liječenih analozima PGF2 u usporedbi s pacijentima bez
liječenja analozima PGF2. Isti trend bio je prisutan kada se analizirala aktivacija MAPK/ERK
signalnog puta mjerenjem izražaja P-ERK1/2. Stanična proliferacija i aktivacija MAPK/ERK
signalnog puta bili su značajno veći u epitelu spojnice u usporedbi sa stromom. Nije bilo
značajne povezanosti između stope proliferacije i aktivacije MAPK/ERK signalnog puta u
stanicama spojnice naših uzoraka.
Zaključci: Naše je istraživanje pokazalo značajno povećanje proliferacije epitelnih i stromalnih
stanica spojnice i aktivaciju MAPK/ERK signalnog puta u bolesnika s glaukomom liječenih
analozima PFG2. Međutim, nije postojala značajna povezanost ova dva procesa što ukazuje da
aktivacija MAPK/ERK signalnog puta vjerojatno ima druge učinke na spojnicu. Daljnja
istraživanja o drugim signalnim putevima povezanim s prostaglandinima mogla bi razjasniti
mehanizam povećane proliferacije u spojnici te dovesti do potencijalnih novih meta za liječenje
nuspojava analoga PGF2
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
The role of social networks in the promotion of associations on the example of a case study
No full textRad opisuje ulogu društvenih mreža u promociji i razvoju udruge za zaštitu životinja “Dog&Go”. Pritom definira društvene mreže i dijeli ih na tri generacije, navodeći najvažnije značajke svake od triju generacija (primjerice interaktivnost, prosječna starost korisnika, način komunikacija, anonimnost i slično). Naposljetku rad sadržava studiju slučaja navedene udruge i njezina djelovanja na društvenim mrežama Facebook i Instagram, kao i prijedloge za daljnje poboljšavanje marketinškog djelovanja.The paper describes the role of social networks in the promotion and development of the "Dog&Go" animal protection association. In doing so, it defines social networks and divides them into three generations, stating the most important features of each of the three generations (for example, interactivity, average age of users, method of communication, anonymity, and so on). Finally, the paper contains a case study of the aforementioned association and its activity on the social networks Facebook and Instagram, as well as suggestions for further improvement of marketing activities
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