610 research outputs found
Social Metadata for Libraries, Archives and Museums. Part 3: Recommendations and Readings
No full textRecommendations on social metadata features most relevant to libraries, archives, and museums and an annotated reading list of the literature the research group consulted during our research. We believe it is riskier to do nothing and become irrelevant to our user communities than to start using social media features
A Simple Ion-exchange Method for the Determination of Sodium, P otassium, Magnesium and Calcium in Human Saliva. Jun Yoshimura and Keisuke Tachi b a n a 41
No full textIntrascrotal epidermoid cyst: report of two cases
No full text1)陰嚢内に発生したepidermoid cystの2例を経験したので報告した.41歳男, 47歳男, Epidermoid cystの診断にはMRIが非常に有用と考えられたA 41-year-old man and a 47-year-old man presented with an intrascrotal mass. The routine studies and ultrasonography showed that the mass was not associated with the testis, epididymis or spermatic cord, but the magnetic resonance imaging was the most useful for making a preoperative diagnosis. Both patients received transscrotal resection of the mass, the histopathological diagnosis of which was epidermoid cyst. A total of 24 cases of epidermoid cyst have been reported in the Japanese literature
昆虫食・昆虫料理をめぐる心理的要因の検討に向けて
No full textOne of the authors, S.Uchiyama, who is conducting bug-eating meetings for several years, has a naive question about the psychological factors why the participants in his meetings are interested in bug-eating. In Section 1, Uchiyama points out the importance of bug-eating and of its popularization.
He explains that insects are rich in nutrition and many are even more nutritionally balanced than meat or fish. In Section 2, the first author, Yoshimura, introduces a psychological study to catch the difference of the attitudes and the senses to the bug-eating between the participants in Uchiyama’s meetings and the general public who have not yet participated in the meetings. Among the conceivable methods, a principal component analysis is used in the present research. Different from the general public, the attitudes and the senses of the participants can not be put into one major component. Yoshimura discusses that the participants in the meetings have multi-phasic attitudes and senses to the bug-eating
A Prospect of Sail-Assisted Fishing Boats
No full textShips are potentially suitable for using wind energy. Almost every ship before the 19th century had been using only the wind power by classic sails, and supporting the worldwide trades and logistics in those days. In 1980’s after the last oil crises, many kind of modern sail-assisted ships were developed. Now, they will be hoped to become one of the best solution against the increasing CO2 discharge. In this paper, the author tries to review the past sail assisted-ships, and investigate into the prospect of the sail-assisted ships especially focusing to the fishing boat in future.Proceedings of International Commemorative Symposium - 70th Anniversary of the Japanese Society of Fisheries Science, October 1-5, 2001, Yokohama (日本水産学会創立70周年記念国際シンポジウム「新世紀における水産・海洋科学の展望」, 2001年10月1日-5日, パシフィコ横浜)
Continuous assay of protein tyrosine phosphatases based on fluorescence resonance energy transfer
No full textAn assay method that continuously measures the protein tyrosine phosphatase (PTP)-catalyzed dephosphorylation reaction based on fluorescence resonance energy transfer (FRET) was developed as an improvement of our previously reported discontinuous version [M. Nishikata, K. Suzuki, Y. Yoshimura, Y. Deyama, A. Matsumoto, Biochem. J. 343 (1999) 385-391]. The assay uses oligopeptide substrates that contain Mca [(7-methoxycoumarin-4-yl)acetyl] group as a fluorescence donor and DNP (2,4-dinitrophenyl) group as a fluorescence acceptor, in addition to a phosphotyrosine residue located between these two groups. In the assay, a PTP solution is added to a buffer solution containing a FRET substrate and chymotrypsin. The PTP-catalyzed dephosphorylation of the substrate and subsequent chymotryptic cleavage of the dephosphorylated substrate results in a disruption of FRET, thereby increasing Mca fluorescence. In this study, we used FRET substrates that are much more susceptible to chymotryptic cleavage after dephosphorylation than the substrate used in our discontinuous assay, thus enabling the continuous assay without significant PTP inactivation by chymotrypsin. The rate of fluorescence increase strictly reflected the rate of dephosphorylation at appropriate chymotrypsin concentrations. Since the continuous assay allows the measurement of initial rate of dephosphorylation reaction, kinetic parameters for the dephosphorylation reactions of a FRET substrate by Yersinia, T-cell and LAR PTPs were determined. The continuous assay was compatible with the measurement of very low PTP activity in a crude enzyme preparation and was comparable in sensitivity to assays that use radiolabeled substrates
Analysis of Muscle Activity Patterns between Two Different Walking Exercise Programs: Qualitative Analysis of Walking Exercise for the Amputee.
No full textP(論文)journal articl
Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients
No full textKenji Yoshimura, Ryoji Maekura, Toru Hiraga, Seigo Kitada, Keisuke Miki, Mari Miki, Yoshitaka TateishiDepartment of Respiratory Medicine, Toneyama National Hospital, Osaka, JapanBackground: Tiotropium partially relieves exertional dyspnea and reduces the risk of congestive heart failure in chronic obstructive pulmonary disease (COPD) patients. However, its effect on the sympathetic activation response to exercise is unknown.Aims: This study aimed to determine whether tiotropium use results in a sustained reduction in sympathetic activation during exercise.Methods: We conducted a 12-week, open-label (treatments: tiotropium 18 µg or oxitropium 0.2 mg × 3 mg), crossover study in 17 COPD patients. Treatment order was randomized across subjects. The subjects underwent a pulmonary function test and two modes of cardiopulmonary exercise (constant work rate and incremental exercise) testing using a cycle ergometer, with measurement of arterial catecholamines after each treatment period.Results: Forced expiratory volume in 1 second and forced vital capacity were significantly larger in the tiotropium treatment group. In constant exercise testing, exercise endurance time was longer, with improvement in dyspnea during exercise and reduction in dynamic hyperinflation in the tiotropium treatment group. Similarly, in incremental exercise testing, exercise time, carbon dioxide production, and minute ventilation at peak exercise were significantly higher in the tiotropium treatment group. Plasma norepinephrine concentrations and dyspnea intensity were also lower during submaximal isotime exercise and throughout the incremental workload exercise in the tiotropium treatment group.Conclusion: Tiotropium suppressed the increase of sympathetic activation during exercise at the end of the 6-week treatment, as compared with the effect of oxipropium. This effect might be attributed to improvement in lung function and exercise capacity and reduction in exertional dyspnea, which were associated with decreases in respiratory frequency and heart rate and reduced progression of arterial acidosis.Keywords: chronic obstructive pulmonary disease (COPD), anticholinergics, exercise testing, sympathetic activation&nbsp
Analysis of Muscle Activity Patterns between Two Different Walking Exercise Programs: Qualitative Analysis of Walking Exercise for the Amputee.
No full textClinical Psychiatric Study of Psychogenic Pain
No full textIn the present study, the author examined clinical psychiatric characteristics in 26 patients who were diagnosed as having Pain Disorder, according to the 4th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). The subjects were 7 males and 19 females. At the onset of pain, the mean age of the patients was 38.8 years. The most common site of pain was the head, followed by the back, arm, and shoulders. In 18 of the 26 patients, there was no evidence of pathological history at the sites where pain was experienced. The accompanying symptoms were insomnia, anxiety, decrease in appetite, analgesic dependence, depressed mood, and astasia-abasia. The author found that various defense mechanisms were acting in their psychological background and that their whole personality was involved in the occurrence of agony. A physician is required to use pharmacotherapy, psychotherapy, or situational therapy depending upon patients' conditions and defense mechanisms
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