1,465 research outputs found
Featured Research: The Failings of NetPromoter
No full textIncludes descriptive metadata provided by producer in MP3 file: "Owen Graduate School of Management - Podcasts - Featured Research: The Failings of NetPromoter - Timothy Keiningham, Senior Vice President and Head of Consulting, Ipsos Loyalty."Owen Graduate School of Managemen
Practical Equality: Discussion with Author Robert L. Tsai
No full textProfessor Timothy Zick discusses a new book titled Practical Equality: Forging Justice in a Divided Nation, with its author, Professor Robert L. Tsai of American University Washington College of Law. Timothy Zick is the John Marshall Professor of Government and Citizenship at William & Mary Law School. His scholarship has explored a wide variety of constitutional issues, with a special focus on the First Amendment. Robert L. Tsai is Professor of Law at American University and a prize-winning essayist in constitutional law and history. Recorded before a live audience at William & Mary Law School on March 14, 2019. The event was sponsored by the American Constitution Society. Professor Tsai was also a panelist during the annual Bill of Rights Journal Symposium on March 15 & 16, 2019
Exploiting Domain Knowledge in Making Delegation Decisions
Get PDF@inproceedings{conf/admi/EmeleNSP11, added-at = {2011-12-19T00:00:00.000+0100}, author = {Emele, Chukwuemeka David and Norman, Timothy J. and Sensoy, Murat and Parsons, Simon}, biburl = {http://www.bibsonomy.org/bibtex/20a08b683088443f1fd36d6ef28bf6615/dblp}, booktitle = {ADMI}, crossref = {conf/admi/2011}, editor = {Cao, Longbing and Bazzan, Ana L. C. and Symeonidis, Andreas L. and Gorodetsky, Vladimir and Weiss, Gerhard and Yu, Philip S.}, ee = {http://dx.doi.org/10.1007/978-3-642-27609-5_9}, interhash = {1d7e7f8554e8bdb3d43c32e02aeabcec}, intrahash = {0a08b683088443f1fd36d6ef28bf6615}, isbn = {978-3-642-27608-8}, keywords = {dblp}, pages = {117-131}, publisher = {Springer}, series = {Lecture Notes in Computer Science}, timestamp = {2011-12-19T00:00:00.000+0100}, title = {Exploiting Domain Knowledge in Making Delegation Decisions.}, url = {http://dblp.uni-trier.de/db/conf/admi/admi2011.html#EmeleNSP11}, volume = 7103, year = 2011
Marker-Based Paternity Test in Polycross Breeding of Timothy
Get PDFAlthough the polycross is a useful and cost effective mating design, a lack of paternal pedigree information is a major limitation for polycross breeding in forage grasses such as timothy (Phleum pratense L.). This study describes a paternity test for use in timothy breeding using polymorphic data on 27 genomic simple sequence repeat markers. The paternity test is a simple exclusion statistical test with a combination of maternal information. It successfully determined paternity (success rate = 97%) for 112 progeny plants derived from three polycross groups (A, B, and D). Indirectly selected paternal parents in polycrosses were inferior to maternal parents directly selected by polycross progeny tests mainly for forage yield. Chi-squared values (χ2) in goodness-of-fit tests of the frequency distribution of paternal parents compared with the expected probabilities revealed unbalanced selection in Polycrosses B and D (χ2 = 141.4*** and 82.7***, respectively). Significant differences among the maternal and paternal parents in breeding values for competitiveness toward legumes and low-digestibility fiber content indicate that unbalanced paternal selection would result from individual phenotypic selection for these traits. These results demonstrate that implementation of a marker-based paternity test in timothy polycross breeding could significantly improve the selection of superior paternal parents and redress problems of parental imbalance
Loyalty myths hyped strategies that will put you out of business and proven tactics that really work
No full textEvaluating Research Impact through Open Access to Scholarly Communication
Get PDFScientific research is a competitive business – in order to secure funding, promotion and tenure researchers must demonstrate their work has impact in their field. To maximise impact researchers undertake high priority research, aim to get results first, and publish in the highest impact journals. The Internet now presents a new opportunity to the scholarly author seeking higher impact: s/he can now make their work instantly accessible on the Web through author self-archiving. This growing body of open access literature (coupled with new publishing models that make journals available for-free to the reader) maximises research impact by maximising the number of people who can read it, and making it available sooner. Open access also provides a new opportunity for bibliometric research. This thesis describes the relatively recent phenomenon of open access to research literature, tools that were built to collect and analyse that literature, and the results of analyses of the effect of open access and its effect on author behaviour. It shows that articles self-archived by authors receive between 50-250% more citations, that rapid pre-printing on the Web has dramatically reduced the peak citation rate from over a year to virtually instant and how citation-impact – now widely used for evaluation – can be expanded to include a new web metric of download impact
Clarinet quintet in A major, K. 581 ; Horn quintet in E-flat major, K. 407 ; Divertimento in D major, K. 251
No full textMore Author/Title Info: Mozart, Wolfgang Amadeus
Physical Description: 1 audio disc : digital ; 4 3/4 in.
Performers: Stanley Drucker, clarinet (1st work) ; Joseph Robinson, oboe (3rd work) ; L. William Kuyper (2nd & 3rd works), R. Allen Spanjer (3rd work), horns ; Timothy Cobb, double bass (3rd work) ; Elysium String quartet (Jennifer Tiboris, Gary Levinson, violins ; Veronica R. Salas, viola ; Lutz Rath, violoncello).
Event Details: Recorded at the American Academy of Arts and Letters, New York City, Sept. 21, Dec. 2 and 6, 1998
Roma, magistra mundi. Itineraria culturae medievalis. Mélanges offerts au Père L.E. Boyle à l\u27occasion de son 75e anniversaire
No full textR. James Long (with Timothy B. Noone) is a contributing author, Fishacre and Rufus on the Metaphysics of Light: Two Unedited Texts , Volume 2, pp. 517-548
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
- …
